Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma

Annals of Allergy, Asthma and Immunology

Volumn 103, Issue 1, 2009, Pages 31-37

  Mehta, Vinay ^a,c   Stokes, Jeffrey R ^b   Berro, Abdo ^b   Romero, Francisco A ^b   Casale, Thomas B ^b  

^a Allergy Asthma and Immunology Associates   (United States)

^b CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METHACHOLINE; METHACHOLINE CHLORIDE; MOMETASONE FUROATE; NITRIC OXIDE;

ADULT; AIRWAY; ARTICLE; ASTHMA; BEDTIME DOSAGE; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG WITHDRAWAL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MALE; PH; PRIORITY JOURNAL; SPIROMETRY; TREATMENT DURATION;

EID: 67650369582     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60140-8     Document Type: Article

References (45)

1. Moorman JE, Rudd RA, Johnson CA, et al. National surveillance for asthma-United States, 1980-2004. MMWR Surveill Summ. 2007;56: 1-54.
2. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J. 2008;31:143-178.
3. Expert Panel Report 3 (EPR-3). Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol. 2007;120(suppl):S94-S138.
4. Michils A, Baldassarre S, Muylem AV. Exhaled nitric oxide and asthma control: a longitudinal study in unselected patients. Eur Respir J. 2008; 31:539-546.
5. Ko FW, Leung TF, Hui DS. Are exhaled breath condensates useful in monitoring asthma? Curr Allergy Asthma Rep. 2007;7:65-71. (Pubitemid 46647029)
6. Gruffydd-Jones K, Ward S, Stonham C, Macfarlane TV, Thomas M. The use of exhaled nitric oxide monitoring in primary care asthma clinics: a pilot study. Prim Care Respir J. 2007;6:349-356.
7. Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med. 2005;352:2163-2173. (Pubitemid 40727083)
8. Chladkova J, Krcmova I, Chladek J, Cap P, Micuda S, Hanzalkova Y. Validation of nitrite and nitrate measurements in exhaled breath condensate. Respiration. 2006;73:173-179.
9. Kostikas K, Papatheodorou G, Ganas K, Psathakis K, Panagou P, Loukides S. pH in expired breath condensate of patients with inflammatory airway diseases. Am J Respir Crit Care Med. 2002;165: 1364-1370. (Pubitemid 34522938)
10. Hunt JF, Fang K, Malik R, et al. Endogenous airway acidification: implications for asthma pathophysiology. Am J Respir Crit Care Med. 2000;161(pt 1):694-699. (Pubitemid 30171718)
11. Brunetti L, Francavilla R, Tesse R, et al. Exhaled breath condensate pH measurement in children with asthma, allergic rhinitis and atopic dermatitis. Pediatr Allergy Immunol. 2006;17:422-427. (Pubitemid 44289471)
12. Barnes PJ. Inhaled glucocorticoids for asthma. N Engl J Med. 1995;332: 868-875.
13. Meltzer EO, Wenzel S. The efficacy and safety of mometasone furoate delivered via a dry powder inhaler for the treatment of asthma. J Asthma. 2006;43:765-772. (Pubitemid 46005583)
14. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general US population. Am J Respir Crit Care Med. 1999;159:179-187. (Pubitemid 29036522)
15. American Thoracic Society. Standardization of Spirometry, 1994 Update. Am J Respir Crit Care Med. 1995;152:1107-1136.
16. Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, Byrns RE. Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine. Proc Natl Acad Sci U S A. 1993;90:8103-8107. (Pubitemid 23260863)
17. Official Statement of the American Thoracic Society. Guidelines for methacholine and exercise challenge testing-1999. Am J Respir Crit Care Med. 2000;161:309-329.
18. Dal Negro R, Micheletto C, Tognella S, Turco P, Rossetti A, Cantini L. Assessment of inhaled BDP-dose dependency of exhaled nitric oxide and local and serum eosinophilic markers in steroids-naïve nonatopic asthmatics. Allergy. 2003;58:1018-1022. (Pubitemid 37260344)
19. Lim S, Jatakanon A, John M, et al. Effect of inhaled budesonide on lung function and airway inflammation. Am J Respir Crit Care Med. 1999; 159:22-30.
20. Kharitonov SA, Donnelly LE, Montuschi P, Corradi M, Collins JV, Barnes PJ. Dose-dependent onset and cessation of action of inhaled budesonide on exhaled nitric oxide and symptoms in mild asthma. Thorax. 2002;57:889-896. (Pubitemid 35178615)
21. Kharitonov SA, Barnes PJ, O'Connor BJ. Reduction in exhaled nitric oxide after a single dose of nebulised budesonide in patients with asthma. Am J Respir Crit Care Med. 1996;153:A799.
22. Guo FH, Comhair SA, Zheng S, et al. Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis. J Immunol. 2000;164: 5970-5980. (Pubitemid 30389845)
23. Hamid Q, Springall D, Riveros-Moreno V, et al. Induction of nitric oxide synthase in asthma. Lancet. 1993;342:1510-1513. (Pubitemid 23362167)
24. Jatakanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax. 1998;53:91-95. (Pubitemid 28212132)
25. Berlyne GS, Parameswaran K, Kamada D, Efthimiadis A, Hargreave FE. A comparison of exhaled nitric oxide and induced sputum as markers of airway inflammation. J Allergy Clin Immunol. 2000;106:638-644. (Pubitemid 30799717)
26. Warke TJ, Fitch PS, Brown V, et al. Exhaled nitric oxide correlates with airway eosinophils in childhood asthma. Thorax. 2002;57:383-387. (Pubitemid 34494145)
27. Lex C, Ferreira F, Zacharasiewicz A, et al. Airway eosinophilia in children with severe asthma: predictive values of noninvasive tests. Am J Respir Crit Care Med. 2006;174:1286-1291. (Pubitemid 44913029)
28. Payne DN, Adcock IM, Wilson NM, Oates T, Scallan M, Bush A. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone. Am J Respir Crit Care Med. 2001;164(pt 1):1376-1381. (Pubitemid 33124013)
29. van Grunsven PM, van Schayck CP, Molema J, Akkermans RP, van Weel C. Effect of inhaled corticosteroids on bronchial responsiveness in patients with "corticosteroid naive" mild asthma: a meta-analysis. Thorax. 1999;54:316-322.
30. Barnes PJ. Effect of corticosteroids on airway hyperresponsiveness. Am Rev Respir Dis. 1990;141:S70-S76.
31. Duddridge M, Ward C, Hendrick DJ, Walters EH. Changes in bronchoalveolar lavage inflammatory cells in asthmatic patients treated with high dose inhaled beclomethasone dipropionate. Eur Respir J. 1993;6: 489-497. (Pubitemid 23135184)
32. Hunt J. Exhaled breath condensate: an evolving tool for non-invasive evaluation of lung disease. J Allergy Clin Immunol. 2002;110:28-34. (Pubitemid 36132721)
33. Vaughan J, Ngamtrakulpanit L, Pajewski T, et al. Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur Respir J. 2003;22:889-894. (Pubitemid 37540637)
34. Nicolaou NC, Lowe LA, Murray CS, Woodcock A, Simpson A, Custovic A. Exhaled breath condensate pH and childhood asthma: unselected birth cohort study. Am J Respir Crit Care Med. 2006;174: 254-259. (Pubitemid 44156603)
35. Ojoo JC, Mulrennan SA, Kastelik JA, Morice AH, Redington AE. Exhaled breath condensate pH and exhaled nitric oxide in allergic asthma and in cystic fibrosis. Thorax. 2005;60:22-26. (Pubitemid 40101013)
36. Ganas K, Loukides S, Papatheodorou G, Panagou P, Kalogeropoulos N. Total nitrite/nitrate in expired breath condensate of patients with asthma. Respir Med. 2001;95:649-654. (Pubitemid 32785520)
37. Ratnawati MJ, Henry RL, Thomas PS. Exhaled breath condensate nitrite/nitrate and pH in relation to pediatric asthma control and exhaled nitric oxide. Pediatr Pulmonol. 2006;41:929-936. (Pubitemid 44534810)
38. Dupont LJ, Rochette F, Demedts MG, Verleden GM. Exhaled nitric oxide correlates with airway hyperresponsiveness in steroid-naive patients with mild asthma. Am J Respir Crit Care Med. 1998;157: 894-898. (Pubitemid 28150705)
39. Zietkowski Z, Bodzenta-Lukaszyk A, Tomasiak MM, Skiepko R, Szmitkowski M. J Investig Allergol Clin Immunol. 2006;16:239-246.
40. Covar R, Szefler S, Martin R, et al. Relations between exhaled nitric oxide and measures of disease activity among children with mild-tomoderate asthma. J Pediatr. 2003;142:469-475. (Pubitemid 36623553)
41. Silvestri M, Sabatini F, Spallarossa D, et al. Exhaled nitric oxide levels in non-allergic and allergic mono-or polysensitised children with asthma. Thorax. 2001;56:857-862. (Pubitemid 32999833)
42. Franklin PJ, Taplin R, Stick SM. A community study of exhaled nitric oxide in healthy children. Am J Respir Crit Care Med. 1999;59:63-73. (Pubitemid 29036505)
43. Kemp JP, Berkowitz RB, Miller SD, Murray JJ, Nolop K, Harrison JE. Mometasone furoate administered once daily is as effective as twicedaily administration for treatment of mild-to-moderate persistent asthma. J Allergy Clin Immunol. 2000;106:485-492. (Pubitemid 32037701)
44. Bensch GW, Prenner B, Berkowitz R, Galant S, Ramsdell J, Lutsky B. Once-daily evening administration of mometasone furoate in asthma treatment initiation. Ann Allergy Asthma Immunol. 2006;96:533-540.
45. Leung TF, Li CY, Yung E, Liu EK, Lam CW, Wong GW. Clinical and technical factors affecting pH and other biomarkers in exhaled breath condensate. Pediatr Pulmonol. 2006;41:87-94. (Pubitemid 43117373)