Update on male contraception

Current Opinion in Obstetrics and Gynecology

Volumn 21, Issue 3, 2009, Pages 265-269

  Naz, Rajesh K ^a,b   Rowan, Shon ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Condom; Contraceptive vaccine; Male contraception; Testosterone; Vasectomy

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; BISDICHLOROACETYLDIAMINE DERIVATIVE; CONTRACEPTIVE VACCINE; DIAMINE DERIVATIVE; ETONOGESTREL; LEVONORGESTREL; MEDROXYPROGESTERONE ACETATE; NORETHISTERONE ENANTATE; SELECTIVE ANDROGEN RECEPTOR MODULATOR; STEROID; TESTOSTERONE; TESTOSTERONE ENANTATE; TESTOSTERONE UNDECANOATE; TRESTOLONE; UNCLASSIFIED DRUG;

ACNE; ANDROGEN BLOOD LEVEL; CLINICAL TRIAL; COITUS; CONDOM; CONTRACEPTION; ERYTHROCYTE COUNT; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; LIBIDO; LIPID BLOOD LEVEL; MOOD CHANGE; PRIORITY JOURNAL; RELIABILITY; REVIEW; SEXUAL BEHAVIOR; SEXUAL FUNCTION; SIDE EFFECT; SPERMATOGENESIS; SWEATING; VASECTOMY; WEIGHT CHANGE; WEIGHT GAIN;

ANDROGEN ANTAGONISTS; ANIMALS; CLINICAL TRIALS AS TOPIC; CONDOMS; CONTRACEPTION; HUMANS; MALE; MODELS, ANIMAL; VASECTOMY;

EID: 67650315670     PISSN: 1040872X     EISSN: None     Source Type: Journal    
DOI: 10.1097/GCO.0b013e328329247d     Document Type: Review

References (39)

1. Henshaw SK. Unintended pregnancy in the United States. Fam Plann Perspect 1998; 30:24-29.
2. Grow DR, Ahmed S. New contraceptive methods. Obstet Gynecol Clin North Am 2000; 27:901 -906.
3. Heinemann K, Saad F, Wiesemes M, et al. Attitudes toward male fertility control: results of a multinational survey on four continents. Hum Reprod 2005; 20:549-556.
4. Weston GC, Schlipalius ML, Bhuinneain MN, Vollenhoven BJ. Will Australian men use male hormonal contraception? A survey of a postpartum population. Med J Aust 2002; 176:208-210.
5. Practice Committee of the American Society for Reproductive Medicine. Hormonal contraception: recent advances and controversies. Fertil Steril 2008; 90:S103-S113.
6. Aitken JR, Baker MA, Doncel GF, et al. As the world grows: contraception in the 21st century. J Clin Invest 2008; 118:1330-1343.
7. Glasier AF, Anakwe R, Everington D, et al. Would women trust their partners to use a male pill? Hum Reprod 2000; 15:646-649.
8. Martin CW, Anderson RA, Cheng L, et al. Potential impact of male hormonal contraception: cross-cultural implications for development of novel preparations. Hum Reprod 2000; 15:637-645.
9. Fu H, Darroch JE, HaasT, Ranjit N. Contraceptive failure rates: new estimates from the 1995 National Survey of Family Growth. Fam Plann Perspect 1999; 31:56-63.
10. Freziers RG, Walsh TL, Nelson AL, et al. Breakage and acceptability of a polyurethane condom: a randomized, controlled study. Fam Plann Perspect 1998; 30:73-78.
11. Practice Committee of the American Society for Reproductive Medicine. Vasectomy reversal. Fertil Steril 2008; 90:S78-S82.
12. Klotz KL, Coppola MA, Labrecque M, et al. Clinical and consumer trial performance of a sensitive immunodiagnostic home test that qualitatively detects low concentrations of sperm following vasectomy. J Urol 2008; 180:2569-2576.
13. Cook LA, Pun A, van Vliet H, et al. Scalpel versus no-scalpel incision for vasectomy. Cochrane Database Syst Rev 2006; CD004112.
14. Guha SK, Singh G, Ansari S, et al. Phase II clinical trial of a vas deferens injectable contraceptive for the male. Contraception 1997; 56:245-250.
15. Koul V, Srivastav A, GuhaSK. Reversibility with sodium bicarbonate of styrene maleic anhydride, an intravasal injectable contraceptive, in male rats. Contraception 1998; 58:227-231.
16. Song L, Gu Y, Lu W, et al. A phase II randomized controlled trial of a novel male contraception, an intra-vas device. Int J Androl 2006; 29:489-495.
17. Sheckter CB, Matsumoto AM, Bremner WJ. Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary. J Clin Endocrinol Metab 1989; 68:397-401.
18. Liu PY, Christenson PD, Handelsman DJ, Wang C. Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis. Lancet 2006; 367:1412-1420.
19. Anderson RA, Baird DT. Male contraception. Endocr Rev 2002; 23:735-762.
20. Liu PY, Swerdloff RS, Anawalt BD, et al. Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis. J Clin Endocrinol Metab 2008; 93:1774-1783.
21. World Health Organization Task Force on methods for the regulation of male fertility. Contraceptive efficacy of testosterone-induced azoospermia in normal men. Lancet 1990; 336:955-959.
22. Meriggiola MC, Costantino A, Saad F, et al. Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection internals on spermatogenesis, reproductive hormones, testis, and prostate. J Clin Endocrinol Metab 2005; 90:2005-2014.
23. Mommers E, Kersemaekers WM, Elliesen J, et al. Male hormonal contra- ception: a double-blind, placebo-controlled study. J Endocrinol Metab 2008; 93:2572-2580.
24. Page ST, Amory JK, Anawalt BD, et al. Testosterone gel combined with depomedroxyprogesterone acetate is and effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist. J Clin Endocrinol Metab 2006; 91:4374-4380.
25. Turner L, Conway AJ, Jimenez M, et al. Contraceptive efficacy of a depot progestin and androgen combination in men. J Clin Endocrinol Metab 2003; 88:4659-4667.
26. Wang C, Wang XH, Nelson AL, et al. Levonorgestrel implants enhanced the suppression of spermatogenesis by testosterone implants: comparison between Chinese and non-Chinese men. Endocrine Care 2006; 91:460-470.
27. Chen J, Hwang DJ, Bohl CE, et al. A selective androgen receptor modulator for hormonal male contraception. J Pharmacol ExpTher2005;312:546-553.
28. Naz RK. Contraceptive vaccines. Drugs 2005; 65:593-603.
29. TalwarGP, Singh O, Pal R, et al. A vaccine that prevents pregnancy in women. Proc Natl Acad Sci USA 1994; 91:8532-8536.
30. Richardson RT, Sivashanmugam P, Hall SH, et al. Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis. Gene 2001; 270:93-102.
31. Robert M, Gagnon C. Purification and characterization of the active precursor of a human sperm motility inhibitor secreted by the seminal vesicles: identity with semenogelin. Biol Reprod 1996; 55:813-821.
32. Wang Z, Widgren E. Association of eppin with semenogelin on human spermatozoa. Biol Reprod 2005; 72:1064-1070.
33. O'Rand MG, Widgen EE, Sivashanmugam P, et al. Reversible immunocon-traception in male monkeys immunized with Eppin. Science 2004; 306:1189-1190.
34. Heller CG, Moore DJ, Paulsen CA. Suppression of spermatogenesis and chronic toxicity in men by a new series of Bis (dichloroacetyl) Diamines. Toxicol Appl Pharmacol 1961; 3:1 -11.
35. Johannson B. A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites. Acta Psychiatr Scand Suppl 1992; 369:15-26.
36. Amory JK. Inhibiting sperm motility for male contraception. Mol Interventions 2007; 7:68-70.
37. Sokal D, McMullen S, Gates D, Dominik R. A comparative study of the no scalpel and standard incision approaches to vasectomy in 5 countries. The Male Sterilization Investigator Team. J Urol 1999; 162:1621-1625.
38. von Eckardstein S, NoeG, Brache V, et al. A clinical trial of 7 alpha-methyl-19-nortestosterone implants for possible use as a long-acting contraceptive for men. J Clin Endocrinol Metab 2003; 88:5232-5239.
39. Jones A, Chen J, Hwang DJ, et al. Preclinical characterization of a (S)-N-(4- cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2- hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology 2009; 150:385-395.