A phase II randomized controlled trial of a novel male contraception, an intra-vas device

International Journal of Andrology

Volumn 29, Issue 4, 2006, Pages 489-495

  Song, L ^a,b   Gu, Y ^a   Lu, W ^a   Liang, X ^a   Chen, Z ^a  

^a NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Male; Methods; Sterilization; Surgery; Vasectomy

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; CHINA; CLINICAL TRIAL; CONTRACEPTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; EPIDIDYMITIS; FOLLOW UP; GRANULOMA; HUMAN; INTRA VAS DEVICE; MAJOR CLINICAL STUDY; MALE; MALE STERILIZATION; PAIN; PATIENT SATISFACTION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RISK; SAFETY; SEMEN ANALYSIS; SEXUAL INTERCOURSE; VASECTOMY;

ADULT; CONTRACEPTIVE DEVICES, MALE; HUMANS; MALE; PATIENT SATISFACTION; SPERM COUNT; VAS DEFERENS; VASECTOMY;

EID: 33745939718     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2006.00686.x     Document Type: Article

References (15)

1. Guha, S. K., Singh, G., Ansari, S., Kumar, S., Srivastava, A., Koul, V., Das, H. C., Malhotra, R. L. & Das, S. K. (1997) Phase II clinical trial of a vas deferens injectable contraceptive for the male. Contraception 56, 245-250.
2. Kar, A. B. & Kamboj, V. P. (1964) Spermatozoa disintegration in rats with an intra-vas deferens device. Indian Journal of Experimental Biology 2, 240-244.
3. Lee, H. Y. (1969) Experimental studies on reversible vas occlusion by intravasal thread. Fertility and Sterility 20, 735-744.
4. Li, S. Q., Goldstein, M. & Zhu, J. (1991) The no-scalpel vasectomy. Journal of Urology 145, 341-344.
5. Liu, X. H., Zhan, B. Y. & Wu, R. Y. (1992) Observation of testis and epididymis histology and ultrastructure after two contraceptions in Macaca mulatta. Nanxing Xue Za Zhi 6, 70-73 [in Chinese].
6. Misro, M. M., Kaur, H., Mahajan, S. & Guha, S. K. (1982) An intravasal non-occlusive contraceptive device in rats. Journal of Reproduction Fertility 65, 9-13.
7. Patel, K. L., Pillai, K. B. D. & Shahni, S. M. (1983) Effect of intravasal copper wire on the fertility and reproductive organs in rats. The Indian Journal of Medical Research 77, 465-471.
8. Schmidt, S. S. (1959) Anastomosis of the vas deferens: an experimental study. III. Dilatation of the vas following obstruction. Journal of Urology 81, 206-208.
9. Sokal, D., McMullen, S., Gates, D. & Dominik, R. (1999) A comparative study of the no scalpel and standard incision approaches to vasectomy in 5 countries. Journal of Urology 162, 1621-1625.
10. WHO (1996) World Health Organization Task Force for the Regulation of Male Fertility. Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men. Fertility and Sterility 65, 821-829.
11. WHO (1999) WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction, 4th edn. Cambridge University Press, Cambridge.
12. Wu, W. X., Yuan, S. J., Chen, Z. W., Gu, Y. Q. & Li, S. Q. (1993) Clinical study of intra-vas device sterilization. Nanxing Xue Za Zhi 7, 34-28 [in Chinese].
13. Wu, W. X., Chen, Z. W., Huang, Z. Q., Li, S. Q., Gu, Y. Q., Pan, B. Q. & Huang, J. C. (1995) Clinical study on efficacy of intra-vas device sterilization. Chinese Journal of Family Planning 330-334.
14. Ye, Y., Chen, Z. W., Xing, Z. J. & Wu, Y. W. (1998) Experimental study of non-occlusive intra-vas device sterilization in rats. Chinese Journal of Family Planning 12, 543-545.
15. Zhan, B. Y., Wu, R. Y., Jin, H. M. & Sun, Y. (1988) Experimental study of an intra-vas filter device as a reversible male contraception. Reproduction and Contraception 8, 56-57.