New S-adenosyl-L-methionine analogues: Synthesis and reactivity studies

Organic Letters

Volumn 11, Issue 14, 2009, Pages 2976-2979

  Townsend, Andrew P ^a   Roth, Stefanie ^a   Williams, Huw E L ^a   Stylianou, Eleni ^b   Thomas, Neil R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5' N CHLOROETHYLAMINO 5' DEOXYADENOSINE; 5'-N-CHLOROETHYLAMINO-5'-DEOXYADENOSINE; AZIRIDINE DERIVATIVE; DEOXYADENOSINE DERIVATIVE; DRUG DERIVATIVE; S ADENOSYLMETHIONINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; PH; PHOTOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AZIRIDINES; DEOXYADENOSINES; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHOTOCHEMISTRY; S-ADENOSYLMETHIONINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67650308454     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol9009859     Document Type: Article

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32. It should be noted that this yield is that after a double purification by column chromatography. The overall yield can be increased by submitting the crude product directly to the next step.