Validation of an LC-MS/MS assay of terpene trilactones in Ginkgo biloba extracts and pharmaceutical formulations through standard addition method

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 3, 2009, Pages 459-468

  Sora, Daniela Iuliana ^a   Stefanescu, Venera ^a   David, Victor ^b   Medvedovici, Andrei ^a,b  

^a LaborMed Pharma SA   (Romania)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

Ginkgo biloba extracts; HPLC; Positive electrospray ionization; Standard addition method; Tandem MS detection; Terpene trilactones; Validation

Indexed keywords

BILOBALIDE; FORMIC ACID; GINKGO BILOBA EXTRACT; GINKGOLIDE A; GINKGOLIDE B; GINKGOLIDE C; GINKGOLIDE J; LACTONE DERIVATIVE; METHANOL; SILICA GEL; TERPENE TRILACTONE; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG FORMULATION; DRUG ISOLATION; DRUG SOLUBILITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFORMATION PROCESSING; PARTICLE SIZE; PRIORITY JOURNAL; PROTON TRANSPORT; REPRODUCIBILITY; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GINKGO BILOBA; LACTONES; PLANT EXTRACTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TERPENES;

EID: 67650260346     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.05.040     Document Type: Article

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