메뉴 건너뛰기




Volumn 283, Issue 1-2, 2009, Pages 187-194

Neuroprotective effect of treatment with galantamine and choline alphoscerate on brain microanatomy in spontaneously hypertensive rats

Author keywords

Cholinergic precursors; Cholinesterase inhibitors; Neuroprotection; Spontaneously hypertensive rats; Vascular dementia

Indexed keywords

AQUAPORIN 4; CHOLINE ALFOSCERATE; CHOLINESTERASE INHIBITOR; GALANTAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2;

EID: 67650146159     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.02.349     Document Type: Article
Times cited : (50)

References (40)
  • 1
    • 1842418653 scopus 로고    scopus 로고
    • Emerging therapies for vascular dementia and vascular cognitive impairment
    • Erkinjuntti T., Román G., Gauthier S., Feldman H., and Rockwood K. Emerging therapies for vascular dementia and vascular cognitive impairment. Stroke 35 (2004) 1010-1017
    • (2004) Stroke , vol.35 , pp. 1010-1017
    • Erkinjuntti, T.1    Román, G.2    Gauthier, S.3    Feldman, H.4    Rockwood, K.5
  • 2
    • 0037387057 scopus 로고    scopus 로고
    • Vascular dementia in a population-based autopsy study
    • Knopman D., Parisi J., Boeve B.F., et al. Vascular dementia in a population-based autopsy study. Arch Neurol 60 (2003) 569-575
    • (2003) Arch Neurol , vol.60 , pp. 569-575
    • Knopman, D.1    Parisi, J.2    Boeve, B.F.3
  • 3
    • 0038076409 scopus 로고    scopus 로고
    • Vascular dementia: distinguishing characteristics, treatment, and prevention
    • Román G.C. Vascular dementia: distinguishing characteristics, treatment, and prevention. J Am Geriatr Soc 51 (2003) S296-S304
    • (2003) J Am Geriatr Soc , vol.51
    • Román, G.C.1
  • 4
    • 0030636350 scopus 로고    scopus 로고
    • Central cholinergic systems and cognition
    • Everitt B.J., and Robbins T.W. Central cholinergic systems and cognition. Annu Rev Psychol 48 (1997) 649-684
    • (1997) Annu Rev Psychol , vol.48 , pp. 649-684
    • Everitt, B.J.1    Robbins, T.W.2
  • 5
    • 0141819867 scopus 로고    scopus 로고
    • Galantamine in the treatment of vascular dementia
    • Brashear H.R. Galantamine in the treatment of vascular dementia. Int Psychogeriatr 15 (2003) 187-193
    • (2003) Int Psychogeriatr , vol.15 , pp. 187-193
    • Brashear, H.R.1
  • 6
    • 34547787131 scopus 로고    scopus 로고
    • Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials
    • Kavirajan H., and Schneider L.S. Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials. Lancet Neurol 6 (2007) 782-792
    • (2007) Lancet Neurol , vol.6 , pp. 782-792
    • Kavirajan, H.1    Schneider, L.S.2
  • 7
    • 3042732149 scopus 로고    scopus 로고
    • Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation
    • Sobrado M., Roda J.M., López M.G., Egea J., and García A.G. Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation. Neurosci Lett 365 (2004) 132-136
    • (2004) Neurosci Lett , vol.365 , pp. 132-136
    • Sobrado, M.1    Roda, J.M.2    López, M.G.3    Egea, J.4    García, A.G.5
  • 8
    • 0344688198 scopus 로고    scopus 로고
    • Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors
    • Arias E., Alés E., Gabilan N.H., Cano-Abad M.F., Villarroya M., García A.G., et al. Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology 46 (2004) 103-114
    • (2004) Neuropharmacology , vol.46 , pp. 103-114
    • Arias, E.1    Alés, E.2    Gabilan, N.H.3    Cano-Abad, M.F.4    Villarroya, M.5    García, A.G.6
  • 9
    • 27744436607 scopus 로고    scopus 로고
    • Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors
    • Arias E., Gallego-Sandín S., Villarroya M., García A.G., and López M.G. Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors. J Pharmacol Exp Ther 315 (2005 Dec) 1346-1353
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1346-1353
    • Arias, E.1    Gallego-Sandín, S.2    Villarroya, M.3    García, A.G.4    López, M.G.5
  • 10
    • 28544434902 scopus 로고    scopus 로고
    • Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons
    • Kume T., Sugimoto M., Takada Y., Yamaguchi T., Yonezawa A., Katsuki H., et al. Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons. Eur J Pharmacol 527 (2005) 77-85
    • (2005) Eur J Pharmacol , vol.527 , pp. 77-85
    • Kume, T.1    Sugimoto, M.2    Takada, Y.3    Yamaguchi, T.4    Yonezawa, A.5    Katsuki, H.6
  • 11
    • 11444262026 scopus 로고    scopus 로고
    • Indicators of neuroprotection with galantamine
    • Geerts H. Indicators of neuroprotection with galantamine. Brain Res Bul 64 (2005) 519-524
    • (2005) Brain Res Bul , vol.64 , pp. 519-524
    • Geerts, H.1
  • 12
    • 29344448251 scopus 로고    scopus 로고
    • Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model
    • Van Dam D., and De Deyn P.P. Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model. Eur Neuropsychopharmacol 16 (2006) 59-69
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 59-69
    • Van Dam, D.1    De Deyn, P.P.2
  • 13
    • 12844271665 scopus 로고    scopus 로고
    • A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?
    • Francis P.T., Nordberg A., and Arnold S.E. A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?. Trends Pharmacol Sci 26 (2005) 104-111
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 104-111
    • Francis, P.T.1    Nordberg, A.2    Arnold, S.E.3
  • 14
    • 0034816672 scopus 로고    scopus 로고
    • Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropriate approaches?
    • Amenta F., Parnetti L., Gallai V., and Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropriate approaches?. Mech Ageing Dev 122 (2001) 2025-2040
    • (2001) Mech Ageing Dev , vol.122 , pp. 2025-2040
    • Amenta, F.1    Parnetti, L.2    Gallai, V.3    Wallin, A.4
  • 15
    • 0034810760 scopus 로고    scopus 로고
    • Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data
    • Parnetti L., Amenta F., and Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data. Mech Ageing Dev 122 (2001) 2041-2055
    • (2001) Mech Ageing Dev , vol.122 , pp. 2041-2055
    • Parnetti, L.1    Amenta, F.2    Gallai, V.3
  • 16
    • 31544469500 scopus 로고    scopus 로고
    • Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission
    • Amenta F., Tayebati S.K., Vitali D., and Di Tullio M.A. Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission. Mech Ageing Dev 127 (2006) 173-179
    • (2006) Mech Ageing Dev , vol.127 , pp. 173-179
    • Amenta, F.1    Tayebati, S.K.2    Vitali, D.3    Di Tullio, M.A.4
  • 17
    • 34249803604 scopus 로고    scopus 로고
    • Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?
    • Parnetti L., Mignini F., Tomassoni D., Traini E., and Amenta F. Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?. J Neurol Sci 257 (2007) 264-269
    • (2007) J Neurol Sci , vol.257 , pp. 264-269
    • Parnetti, L.1    Mignini, F.2    Tomassoni, D.3    Traini, E.4    Amenta, F.5
  • 18
    • 0034648716 scopus 로고    scopus 로고
    • The hippocampus in spontaneously hypertensive rats: a quantitative microanatomical study
    • Sabbatini M., Strocchi P., Vitaioli L., and Amenta F. The hippocampus in spontaneously hypertensive rats: a quantitative microanatomical study. Neuroscience 100 (2000) 251-258
    • (2000) Neuroscience , vol.100 , pp. 251-258
    • Sabbatini, M.1    Strocchi, P.2    Vitaioli, L.3    Amenta, F.4
  • 19
    • 0034805717 scopus 로고    scopus 로고
    • Hypertensive brain damage: comparative evaluation of protective effect of treatment with dihydropyridine derivatives in spontaneously hypertensive rats
    • Sabbatini M., Tomassoni D., and Amenta F. Hypertensive brain damage: comparative evaluation of protective effect of treatment with dihydropyridine derivatives in spontaneously hypertensive rats. Mech Ageing Dev 122 (2001) 2085-2105
    • (2001) Mech Ageing Dev , vol.122 , pp. 2085-2105
    • Sabbatini, M.1    Tomassoni, D.2    Amenta, F.3
  • 20
    • 33748096585 scopus 로고    scopus 로고
    • What constitutes clinical evidence for neuroprotection in Alzheimer disease: support for the cholinesterase inhibitors?
    • Mori E., Hashimoto M., Krishnan K.R., and Doraiswamy P.M. What constitutes clinical evidence for neuroprotection in Alzheimer disease: support for the cholinesterase inhibitors?. Alzheimer Dis Assoc Disord 20 (2006) S19-26
    • (2006) Alzheimer Dis Assoc Disord , vol.20
    • Mori, E.1    Hashimoto, M.2    Krishnan, K.R.3    Doraiswamy, P.M.4
  • 21
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond
    • Lipton S.A. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat Rev Drug Discov 5 (2006) 160-170
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 22
    • 34948842904 scopus 로고    scopus 로고
    • Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse
    • Parsons C.G., Stöffler A., and Danysz W. Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse. Neuropharmacology 53 (2007) 699-723
    • (2007) Neuropharmacology , vol.53 , pp. 699-723
    • Parsons, C.G.1    Stöffler, A.2    Danysz, W.3
  • 23
    • 33748094425 scopus 로고    scopus 로고
    • Preclinical evidence of neuroprotection by cholinesterase inhibitors
    • Akaike A. Preclinical evidence of neuroprotection by cholinesterase inhibitors. Alzheimer Dis Assoc Disord 20 (2006) S8-11
    • (2006) Alzheimer Dis Assoc Disord , vol.20
    • Akaike, A.1
  • 24
    • 0030682093 scopus 로고    scopus 로고
    • Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. I
    • Gattu M., Pauly J.R., Boss K.L., Summers J.B., and Buccafusco J.J. Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. I. Brain Res 771 (1997) 89-103
    • (1997) Brain Res , vol.771 , pp. 89-103
    • Gattu, M.1    Pauly, J.R.2    Boss, K.L.3    Summers, J.B.4    Buccafusco, J.J.5
  • 25
    • 0030664205 scopus 로고    scopus 로고
    • Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. Part II
    • Gattu M., Terry Jr. A.V., Pauly J.R., and Buccafusco J.J. Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. Part II. Brain Res 771 (1997) 104-114
    • (1997) Brain Res , vol.771 , pp. 104-114
    • Gattu, M.1    Terry Jr., A.V.2    Pauly, J.R.3    Buccafusco, J.J.4
  • 26
    • 0032742750 scopus 로고    scopus 로고
    • Changes in nicotinic acetylcholine receptor subunit mRNAs and nicotinic binding in spontaneously hypertensive stroke prone rats
    • Ferrari R., Frasoldati A., Leo G., Torri C., Zini I., Agnati L.F., et al. Changes in nicotinic acetylcholine receptor subunit mRNAs and nicotinic binding in spontaneously hypertensive stroke prone rats. Neurosci Lett 277 (1999) 169-172
    • (1999) Neurosci Lett , vol.277 , pp. 169-172
    • Ferrari, R.1    Frasoldati, A.2    Leo, G.3    Torri, C.4    Zini, I.5    Agnati, L.F.6
  • 27
    • 0034619586 scopus 로고    scopus 로고
    • Deficits in spatial learning and nicotinic-acetylcholine receptors in older, spontaneously hypertensive rats
    • Terry Jr. A.V., Hernandez C.M., Buccafusco J.J., and Gattu M. Deficits in spatial learning and nicotinic-acetylcholine receptors in older, spontaneously hypertensive rats. Neuroscience 101 (2000) 357-368
    • (2000) Neuroscience , vol.101 , pp. 357-368
    • Terry Jr., A.V.1    Hernandez, C.M.2    Buccafusco, J.J.3    Gattu, M.4
  • 28
    • 0037831127 scopus 로고    scopus 로고
    • Spontaneously hypertensive rats: further evaluation of age-related memory performance and cholinergic marker expression
    • Hernandez C.M., Høifødt H., and Terry Jr. A.V. Spontaneously hypertensive rats: further evaluation of age-related memory performance and cholinergic marker expression. J Psychiatry Neurosci 28 (2003) 197-209
    • (2003) J Psychiatry Neurosci , vol.28 , pp. 197-209
    • Hernandez, C.M.1    Høifødt, H.2    Terry Jr., A.V.3
  • 29
    • 19444374184 scopus 로고    scopus 로고
    • Effect of repeated nicotine exposure on high-affinity nicotinic acetylcholine receptor density in spontaneously hypertensive rats
    • Hohnadel E.J., Hernandez C.M., Gearhart D.A., and Terry Jr. A.V. Effect of repeated nicotine exposure on high-affinity nicotinic acetylcholine receptor density in spontaneously hypertensive rats. Neurosci Lett 382 (2005) 158-163
    • (2005) Neurosci Lett , vol.382 , pp. 158-163
    • Hohnadel, E.J.1    Hernandez, C.M.2    Gearhart, D.A.3    Terry Jr., A.V.4
  • 30
    • 0345552469 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors: involvement in Alzheimer's disease and schizophrenia
    • Woodruff-Pak D.S., and Gould T.J. Neuronal nicotinic acetylcholine receptors: involvement in Alzheimer's disease and schizophrenia. Behav Cogn Neurosci Rev 1 (2002) 5-20
    • (2002) Behav Cogn Neurosci Rev , vol.1 , pp. 5-20
    • Woodruff-Pak, D.S.1    Gould, T.J.2
  • 31
    • 38449098712 scopus 로고    scopus 로고
    • Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
    • Picciotto M.R., and Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Front Biosci 13 (2008) 492-504
    • (2008) Front Biosci , vol.13 , pp. 492-504
    • Picciotto, M.R.1    Zoli, M.2
  • 33
    • 0026541527 scopus 로고
    • l-alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat
    • Sigala S., Imperato A., Rizzonelli P., Casolini P., Missale C., and Spano P. l-alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eur J Pharmacol 211 (1992) 351-358
    • (1992) Eur J Pharmacol , vol.211 , pp. 351-358
    • Sigala, S.1    Imperato, A.2    Rizzonelli, P.3    Casolini, P.4    Missale, C.5    Spano, P.6
  • 34
    • 0027370167 scopus 로고
    • Cholinergic neurotransmission in the hippocampus of aged rats: influence of l-alpha-glycerylphosphorylcholine treatment
    • Amenta F., Franch F., Ricci A., and Vega J.A. Cholinergic neurotransmission in the hippocampus of aged rats: influence of l-alpha-glycerylphosphorylcholine treatment. Ann N Y Acad Sci 695 (1993) 311-313
    • (1993) Ann N Y Acad Sci , vol.695 , pp. 311-313
    • Amenta, F.1    Franch, F.2    Ricci, A.3    Vega, J.A.4
  • 35
    • 0027563450 scopus 로고
    • Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile dementia of Alzheimer's type
    • Parnetti L., Abate G., Bartorelli L., Cucinotta D., Cuzzupoli M., Maggioni M., et al. Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile dementia of Alzheimer's type. Drugs Aging 3 (1993) 159-164
    • (1993) Drugs Aging , vol.3 , pp. 159-164
    • Parnetti, L.1    Abate, G.2    Bartorelli, L.3    Cucinotta, D.4    Cuzzupoli, M.5    Maggioni, M.6
  • 36
    • 0028041589 scopus 로고
    • Muscarinic cholinergic receptors in the hippocampus of aged rats: influence of choline alphoscerate treatment
    • Amenta F., Liu A., Zeng Y.C., and Zaccheo D. Muscarinic cholinergic receptors in the hippocampus of aged rats: influence of choline alphoscerate treatment. Mech Ageing Dev 76 (1994) 49-64
    • (1994) Mech Ageing Dev , vol.76 , pp. 49-64
    • Amenta, F.1    Liu, A.2    Zeng, Y.C.3    Zaccheo, D.4
  • 37
    • 0028279184 scopus 로고
    • alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial
    • Barbagallo Sangiorgi G., Barbagallo M., Giordano M., Meli M., and Panzarasa R. alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial. Ann N Y Acad Sci 717 (1994) 253-269
    • (1994) Ann N Y Acad Sci , vol.717 , pp. 253-269
    • Barbagallo Sangiorgi, G.1    Barbagallo, M.2    Giordano, M.3    Meli, M.4    Panzarasa, R.5
  • 38
    • 0029898003 scopus 로고    scopus 로고
    • Effect of l-alpha glycerylphosphorylcholine on muscarinic receptors and membrane microviscosity of aged rat brain
    • Muccioli G., Raso G.M., Ghé C., and Di Carlo R. Effect of l-alpha glycerylphosphorylcholine on muscarinic receptors and membrane microviscosity of aged rat brain. Prog Neuropsychopharmacol Biol Psychiatry 20 (1996) 323-339
    • (1996) Prog Neuropsychopharmacol Biol Psychiatry , vol.20 , pp. 323-339
    • Muccioli, G.1    Raso, G.M.2    Ghé, C.3    Di Carlo, R.4
  • 39
    • 33750489013 scopus 로고    scopus 로고
    • Effect of treatment with choline alphoscerate on hippocampus microanatomy and glial reaction in spontaneously hypertensive rats
    • Tomassoni D., Avola R., Mignini F., Parnetti L., and Amenta F. Effect of treatment with choline alphoscerate on hippocampus microanatomy and glial reaction in spontaneously hypertensive rats. Brain Res 1120 (2006) 183-190
    • (2006) Brain Res , vol.1120 , pp. 183-190
    • Tomassoni, D.1    Avola, R.2    Mignini, F.3    Parnetti, L.4    Amenta, F.5
  • 40
    • 0037086811 scopus 로고    scopus 로고
    • The hippocampus in spontaneously hypertensive rats: an animal model of vascular dementia?
    • Sabbatini M., Catalani A., Consoli C., Marletta N., Tomassoni D., and Avola R. The hippocampus in spontaneously hypertensive rats: an animal model of vascular dementia?. Mech Ageing Dev 123 (2002) 547-559
    • (2002) Mech Ageing Dev , vol.123 , pp. 547-559
    • Sabbatini, M.1    Catalani, A.2    Consoli, C.3    Marletta, N.4    Tomassoni, D.5    Avola, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.