메뉴 건너뛰기




Volumn 583, Issue 14, 2009, Pages 2414-2418

Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells

Author keywords

Biological half life; CagA; Gastric carcinoma; Helicobacter pylori; PAR1; Virulence factor

Indexed keywords

CAGA PROTEIN; ONCOPROTEIN; PARTITIONING DEFECTIVE 1; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; UNCLASSIFIED DRUG;

EID: 67650101208     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.06.043     Document Type: Article
Times cited : (26)

References (15)
  • 1
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek Jr. R.M., and Blaser M.J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2 (2002) 28-37
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 28-37
    • Peek Jr., R.M.1    Blaser, M.J.2
  • 2
    • 0033456273 scopus 로고    scopus 로고
    • Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
    • Segal E.D., Cha J., Lo J., Falkow S., and Tompkins L.S. Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc. Natl. Acad. Sci. USA 96 (1999) 14559-14564
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14559-14564
    • Segal, E.D.1    Cha, J.2    Lo, J.3    Falkow, S.4    Tompkins, L.S.5
  • 3
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of the Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit S., Püls J., Sedlmaier B., Gerland E., Fischer W., and Haas R. Translocation of the Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287 (2000) 1497-1500
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1    Püls, J.2    Sedlmaier, B.3    Gerland, E.4    Fischer, W.5    Haas, R.6
  • 5
    • 0036510363 scopus 로고    scopus 로고
    • Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo
    • Selbach M., Moese S., Hauck C.R., Meyer T.F., and Backert S. Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J. Biol. Chem. 277 (2002) 6775-6778
    • (2002) J. Biol. Chem. , vol.277 , pp. 6775-6778
    • Selbach, M.1    Moese, S.2    Hauck, C.R.3    Meyer, T.F.4    Backert, S.5
  • 6
    • 0036227053 scopus 로고    scopus 로고
    • C-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
    • Stein M., Bagnoli F., Halenbeck R., Rappuoli R., Fantl W.J., and Covacci A. C-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol. Microbiol. 43 (2002) 971-980
    • (2002) Mol. Microbiol. , vol.43 , pp. 971-980
    • Stein, M.1    Bagnoli, F.2    Halenbeck, R.3    Rappuoli, R.4    Fantl, W.J.5    Covacci, A.6
  • 7
    • 0037169076 scopus 로고    scopus 로고
    • SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein
    • Higashi H., Tsutsumi R., Muto S., Sugiyama T., Azuma T., Asaka M., and Hatakeyama M. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science 295 (2002) 683-686
    • (2002) Science , vol.295 , pp. 683-686
    • Higashi, H.1    Tsutsumi, R.2    Muto, S.3    Sugiyama, T.4    Azuma, T.5    Asaka, M.6    Hatakeyama, M.7
  • 8
    • 4544334936 scopus 로고    scopus 로고
    • Oncogenic mechanisms of Helicobacter pylori CagA protein
    • Hatakeyama M. Oncogenic mechanisms of Helicobacter pylori CagA protein. Nat. Rev. Cancer 4 (2004) 688-694
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 688-694
    • Hatakeyama, M.1
  • 10
    • 33845943988 scopus 로고    scopus 로고
    • Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells
    • Ren S., Higashi H., Lu H., Azuma T., and Hatakeyama M. Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells. J. Biol. Chem. 27 281 (2006) 32344-32352
    • (2006) J. Biol. Chem. , vol.27 , Issue.281 , pp. 32344-32352
    • Ren, S.1    Higashi, H.2    Lu, H.3    Azuma, T.4    Hatakeyama, M.5
  • 11
    • 40849085080 scopus 로고    scopus 로고
    • SagA of CagA in Helicobacter pylori pathogenesis
    • Hatakeyama M. SagA of CagA in Helicobacter pylori pathogenesis. Curr. Opin. Microbiol. 11 (2008) 30-37
    • (2008) Curr. Opin. Microbiol. , vol.11 , pp. 30-37
    • Hatakeyama, M.1
  • 13
    • 0037195107 scopus 로고    scopus 로고
    • Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
    • Higashi H., Tsutsumi R., Fujita A., Yamazaki S., Asaka M., Azuma T., and Hatakeyama M. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc. Natl. Acad. Sci. USA 99 (2002) 14428-14433
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14428-14433
    • Higashi, H.1    Tsutsumi, R.2    Fujita, A.3    Yamazaki, S.4    Asaka, M.5    Azuma, T.6    Hatakeyama, M.7
  • 14
    • 54949087520 scopus 로고    scopus 로고
    • Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA
    • Lu H.S., Saito Y., Umeda M., Murata-Kamiya N., Zhang H.M., Higashi H., and Hatakeyama M. Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA. Cancer Sci. 99 (2008) 2004-2011
    • (2008) Cancer Sci. , vol.99 , pp. 2004-2011
    • Lu, H.S.1    Saito, Y.2    Umeda, M.3    Murata-Kamiya, N.4    Zhang, H.M.5    Higashi, H.6    Hatakeyama, M.7
  • 15
    • 2342567852 scopus 로고    scopus 로고
    • Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation
    • Stommel J.M., and Wahl G.M. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation. EMBO J. 23 (2004) 1547-1556
    • (2004) EMBO J. , vol.23 , pp. 1547-1556
    • Stommel, J.M.1    Wahl, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.