-
1
-
-
0033591290
-
Helicobacter pylori virulence and genetic geography
-
Covacci A, Telfold JL, Del Giudice G, Parsonnet J, Rappuoli R. Helicobacter pylori virulence and genetic geography. Science 1999; 284: 1328-33.
-
(1999)
Science
, vol.284
, pp. 1328-1333
-
-
Covacci, A.1
Telfold, J.L.2
Del Giudice, G.3
Parsonnet, J.4
Rappuoli, R.5
-
2
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas
-
Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002; 2: 28-37.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 28-37
-
-
Peek Jr., R.M.1
Blaser, M.J.2
-
3
-
-
30344457320
-
Helicobacter pylori CagA: A new paradigm for bacterial carcinogenesis
-
Hatakeyama M, Higashi H. Helicobacter pylori CagA: A new paradigm for bacterial carcinogenesis. Cancer Sci 2005; 96: 835-43.
-
(2005)
Cancer Sci
, vol.96
, pp. 835-843
-
-
Hatakeyama, M.1
Higashi, H.2
-
4
-
-
0027173990
-
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
-
Covacci A, Censini S, Bugnoli M et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993; 90: 5791-5.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5791-5795
-
-
Covacci, A.1
Censini, S.2
Bugnoli, M.3
-
5
-
-
0027230726
-
Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production
-
Tummuru MK, Cover TL, Blaster MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production. Infect Immun 1993; 61: 1799-809.
-
(1993)
Infect Immun
, vol.61
, pp. 1799-1809
-
-
Tummuru, M.K.1
Cover, T.L.2
Blaster, M.J.3
-
6
-
-
0033456273
-
Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
-
Segal ED, Cha J, Lo J, Falkow S, Tompkins LS. Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci USA 1999; 96: 14559-64.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14559-14564
-
-
Segal, E.D.1
Cha, J.2
Lo, J.3
Falkow, S.4
Tompkins, L.S.5
-
7
-
-
0036510363
-
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo
-
Selbach M, Moese S, Hauck CR, Mayer TF, Backert S. Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem 2002; 277: 6775-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 6775-6778
-
-
Selbach, M.1
Moese, S.2
Hauck, C.R.3
Mayer, T.F.4
Backert, S.5
-
8
-
-
0036227053
-
c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
-
Stein M, Bagnoli F, Halenback R, Rappuoli R, Fantl WJ, Covacci A. c-Src/ Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol Microbiol 2002; 43: 971-80.
-
(2002)
Mol Microbiol
, vol.43
, pp. 971-980
-
-
Stein, M.1
Bagnoli, F.2
Halenback, R.3
Rappuoli, R.4
Fantl, W.J.5
Covacci, A.6
-
9
-
-
34247255905
-
Activation of the Abl by Helicobacter pylori. a novel kinase for the CagA and crucial mediator of host cell scattering
-
Tammer I, Brandt S, Hartig R, Konig W, Backert S. Activation of the Abl by Helicobacter pylori. a novel kinase for the CagA and crucial mediator of host cell scattering. Gastroenterology 2007; 132: 1309-19.
-
(2007)
Gastroenterology
, vol.132
, pp. 1309-1319
-
-
Tammer, I.1
Brandt, S.2
Hartig, R.3
Konig, W.4
Backert, S.5
-
10
-
-
34249308195
-
Phosphorylation Helicobacter pylori CagA by c-Abl leads to cell motility
-
Poppe M, Feller SM, Romer G, Wessler S. Phosphorylation Helicobacter pylori CagA by c-Abl leads to cell motility. Oncogene 2007; 26: 3462-72.
-
(2007)
Oncogene
, vol.26
, pp. 3462-3472
-
-
Poppe, M.1
Feller, S.M.2
Romer, G.3
Wessler, S.4
-
11
-
-
0037169076
-
SHP-2 tyrosine phosphatase is an intracellular target of Helicobacter pylori CagA protein
-
Higashi H, Tsutsumi R, Muto S et al. SHP-2 tyrosine phosphatase is an intracellular target of Helicobacter pylori CagA protein. Science 2002; 295: 683-6.
-
(2002)
Science
, vol.295
, pp. 683-686
-
-
Higashi, H.1
Tsutsumi, R.2
Muto, S.3
-
12
-
-
4544334936
-
Oncogenic mechanisms of the Helicobacter pylori CagA protein
-
Hatakeyama M. Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer 2004; 4: 688-94.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 688-694
-
-
Hatakeyama, M.1
-
13
-
-
0036809776
-
Grb2 is a key mediator of Helicobacter pylori CagA protein activities
-
Mimuro H, Suzuki J, Tanaka J, Asahi M, Haas R, Sasakawa H. Grb2 is a key mediator of Helicobacter pylori CagA protein activities. Mol Cell 2002; 10: 745-55.
-
(2002)
Mol Cell
, vol.10
, pp. 745-755
-
-
Mimuro, H.1
Suzuki, J.2
Tanaka, J.3
Asahi, M.4
Haas, R.5
Sasakawa, H.6
-
14
-
-
0037732638
-
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response
-
Churin Y, Al-Ghoul L, Kepp O, Meyer TF, Birchmeier W, Naumann M. Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response. J Cell Biol 2003; 161: 249-55.
-
(2003)
J Cell Biol
, vol.161
, pp. 249-255
-
-
Churin, Y.1
Al-Ghoul, L.2
Kepp, O.3
Meyer, T.F.4
Birchmeier, W.5
Naumann, M.6
-
15
-
-
0037423309
-
Attenuation of Helicobacter pylori CagA × SHP-2 signaling by interaction between CagA and C-terminal Src kinase
-
Tsutsumi R, Higashi H, Higuchi M, Okada M, Hatakeyama M. Attenuation of Helicobacter pylori CagA × SHP-2 signaling by interaction between CagA and C-terminal Src kinase. J Biol Chem 2003; 278: 3664-70.
-
(2003)
J Biol Chem
, vol.278
, pp. 3664-3670
-
-
Tsutsumi, R.1
Higashi, H.2
Higuchi, M.3
Okada, M.4
Hatakeyama, M.5
-
16
-
-
27744471043
-
Interaction of CagA with Crk plays an important role in Helicobacter pylori -induced loss of gastric epithelial cell adhesion
-
Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C. Interaction of CagA with Crk plays an important role in Helicobacter pylori -induced loss of gastric epithelial cell adhesion. J Exp Med 2005; 202: 1235-47.
-
(2005)
J Exp Med
, vol.202
, pp. 1235-1247
-
-
Suzuki, M.1
Mimuro, H.2
Suzuki, T.3
Park, M.4
Yamamoto, T.5
Sasakawa, C.6
-
17
-
-
34249090814
-
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
-
Saadat I, Higashi H, Obuse C et al. Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature 2007; 447: 330-3.
-
(2007)
Nature
, vol.447
, pp. 330-333
-
-
Saadat, I.1
Higashi, H.2
Obuse, C.3
-
18
-
-
38849168048
-
Analysis of detergent-resistant membranes of Helicobacter pylori infected gastric adenocarcinoma cells reveals a role for MARK2/Par1b in CagA-mediated disruption of cellular polarity
-
Zealer Z, Cohen D, Musch A, Bagnoli F, Covacci A, Stein M. Analysis of detergent-resistant membranes of Helicobacter pylori infected gastric adenocarcinoma cells reveals a role for MARK2/Par1b in CagA-mediated disruption of cellular polarity. Cell Microbiol 2008; 10: 781-94.
-
(2008)
Cell Microbiol
, vol.10
, pp. 781-794
-
-
Zealer, Z.1
Cohen, D.2
Musch, A.3
Bagnoli, F.4
Covacci, A.5
Stein, M.6
-
19
-
-
38949199463
-
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
-
Onishi N, Yuasa H, Tanaka S et al. Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci USA 2008; 105: 1003-8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1003-1008
-
-
Onishi, N.1
Yuasa, H.2
Tanaka, S.3
-
20
-
-
0037195107
-
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
-
Higashi H, Tsutsumi R, Fujita A et al. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc Natl Acad Sci USA 2002; 99: 14428-33.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14428-14433
-
-
Higashi, H.1
Tsutsumi, R.2
Fujita, A.3
-
21
-
-
20744458702
-
EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells
-
Higashi H, Yokoyama K, Fujii Y et al. EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells. J Biol Chem 2005; 280: 23130-7.
-
(2005)
J Biol Chem
, vol.280
, pp. 23130-23137
-
-
Higashi, H.1
Yokoyama, K.2
Fujii, Y.3
-
22
-
-
33646016600
-
Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA
-
Naito M, Yamazaki T, Tsutsumi R et al. Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA. Gastroenterology 2006; 130: 1181-90.
-
(2006)
Gastroenterology
, vol.130
, pp. 1181-1190
-
-
Naito, M.1
Yamazaki, T.2
Tsutsumi, R.3
-
23
-
-
33845943988
-
Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells
-
Ren S, Higashi H, Lu H, Azuma T, Hatakeyama M. Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells. J Biol Chem 2006; 281: 32344-52.
-
(2006)
J Biol Chem
, vol.281
, pp. 32344-32352
-
-
Ren, S.1
Higashi, H.2
Lu, H.3
Azuma, T.4
Hatakeyama, M.5
-
25
-
-
19044366273
-
Helicobacter pylori cag-type IV secretion system facilitates corpus colonization to induce precancerous conditions in Mongolian gerbils
-
Rieder G, Merchant JL, Haas R. Helicobacter pylori cag-type IV secretion system facilitates corpus colonization to induce precancerous conditions in Mongolian gerbils. Gastroenterology 2005; 128: 1229-42.
-
(2005)
Gastroenterology
, vol.128
, pp. 1229-1242
-
-
Rieder, G.1
Merchant, J.L.2
Haas, R.3
-
26
-
-
4043170088
-
Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors
-
Bilder D. Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors. Genes Dev 2004; 18: 1909-25.
-
(2004)
Genes Dev
, vol.18
, pp. 1909-1925
-
-
Bilder, D.1
-
27
-
-
2942729619
-
LKB1 tumor suppressor protein: PARtaker in cell polarity
-
Baas AF, Smit L, Clevers H. LKB1 tumor suppressor protein: PARtaker in cell polarity. Trends Cell Biol 2004; 14: 312-19.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 312-319
-
-
Baas, A.F.1
Smit, L.2
Clevers, H.3
-
28
-
-
2342429370
-
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation
-
Higashi H, Nakaya A, Tsutsumi R et al. Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem 2004; 279: 17205-16.
-
(2004)
J Biol Chem
, vol.279
, pp. 17205-17216
-
-
Higashi, H.1
Nakaya, A.2
Tsutsumi, R.3
-
29
-
-
12144291018
-
Association between diversity in the Src homology 2 domain-containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer
-
Azuma T, Yamazaki S, Yamakawa A et al. Association between diversity in the Src homology 2 domain-containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer. J Infect Dis 2004; 89: 820-7.
-
(2004)
J Infect Dis
, vol.89
, pp. 820-837
-
-
Azuma, T.1
Yamazaki, S.2
Yamakawa, A.3
-
30
-
-
4143096988
-
Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori
-
Argent RH, Kidd M, Owen RJ, Thomas RJ, Limb MC, Atherton JC. Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterology 2004; 127: 514-23.
-
(2004)
Gastroenterology
, vol.127
, pp. 514-523
-
-
Argent, R.H.1
Kidd, M.2
Owen, R.J.3
Thomas, R.J.4
Limb, M.C.5
Atherton, J.C.6
-
31
-
-
46049098358
-
Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
-
doi: 10.1053/j.gastro.2008.03.041
-
Basso D, Zambon CF, Letley DP et al. Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology doi: 10.1053/ j.gastro.2008.03.041.
-
Gastroenterology
-
-
Basso, D.1
Zambon, C.F.2
Letley, D.P.3
-
32
-
-
34447285051
-
Heterogeneity in the activity of Mexican Helicobacter pylori strains in gastric epithelial cells and its association with diversity in the cagA gene
-
Reyes-Leon A, Atherton JC, Argent RH, Puente JL, Torres J. Heterogeneity in the activity of Mexican Helicobacter pylori strains in gastric epithelial cells and its association with diversity in the cagA gene. Infect Immun 2007; 75: 3345-54.
-
(2007)
Infect Immun
, vol.75
, pp. 3345-3354
-
-
Reyes-Leon, A.1
Atherton, J.C.2
Argent, R.H.3
Puente, J.L.4
Torres, J.5
-
33
-
-
2942622320
-
Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan
-
Azuma T, Yamakawa A, Yamazaki S et al. Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan. J Clin Microbiol 2004; 42: 2508-17.
-
(2004)
J Clin Microbiol
, vol.42
, pp. 2508-2517
-
-
Azuma, T.1
Yamakawa, A.2
Yamazaki, S.3
|