Tablet dissolution affected by a moisture mediated solid-state interaction between drug and disintegrant

Pharmaceutical Research

Volumn 16, Issue 12, 1999, Pages 1850-1856

  Rohrs, Brian R ^a   Thamann, Thomas J ^a   Gao, Ping ^a   Stelzer, Dennis J ^a   Bergren, Micheal S ^a   Chao, Robert S ^a  

^a PFIZER INC   (United States)

Author keywords

CP MAS NMR; Croscarmellose sodium; Disintegrant; Dissolution; Infrared spectroscopy; Solid state reaction; Tablet stability

Indexed keywords

CARBOXYL GROUP; CROSCARMELLOSE SODIUM; DELAVIRDINE; DISINTEGRATING AGENT; MESYLIC ACID; WATER;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL INTERACTION; DRUG SOLUBILITY; DRUG STABILITY; HUMIDITY; INFRARED SPECTROSCOPY; MOISTURE; PRIORITY JOURNAL; SOLID STATE; TABLET DISINTEGRATION; TABLET MATRIX; WATER CONTENT;

EID: 0033403992     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018951309506     Document Type: Article

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