Stereocontrolled synthesis of 1,3-amino alcohols by reduction of substituted 2-{1-[(tert-butylsulfinyl)amino]alkyl}cyclohexanones

Synthesis

Volumn , Issue 12, 2009, Pages 2083-2088

  González Gómez, José C ^a   Foubelo, Francisco ^a   Yus, Miguel ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

Author keywords

Amino alcohols; Ketones; Multicomponent reaction; Phosphoramidites; Reduction; Stereoselectivity

Indexed keywords

AMINO ALCOHOLS; CYCLOHEXANONE; CYCLOHEXANONES; DIETHYLZINC; MULTICOMPONENT REACTION; PHOSPHORAMIDITE LIGANDS; PHOSPHORAMIDITES; SODIUM BOROHYDRIDE; STEREOCONTROLLED SYNTHESIS; STEREOGENIC CENTERS;

ALCOHOLS; AMINATION; KETONES; SODIUM; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL);

AMINES;

1,3 AMINO ALCOHOL; 2 [1[(TERT BUTYLSULFINYL)AMINO]ALKYL]CYCLOHEXANONE; 2 [[(TERT BUTYLSULFINYL)AMINO]METHYL]CYCLOHEXANONE; 2 CYCLOHEXENONE; ALCOHOL DERIVATIVE; ALKANOL; BETA AMINO CYCLOALKANOL; BETA SULFINYLAMINO CYCLOHEXANONE; BORANE DERIVATIVE; CYCLOHEXANONE; CYCLOHEXANONE DERIVATIVE; DIETHYLZINC; IMINE; LITHIUM TRIETHYLBOROHYDRIDE; N [1 [2 ETHYL 6 OXOCYCLOHEXYL] 3 PHENYLPROPYL] 2 METHYLPROPANE 2 SULFINAMIDE; N [1[2 ETHYL 6 HYDROXYCYCLOHEXYL] 3 PHENYLPROPYL] 2 METHYLPROPANE 2 SULFINAMIDE; N [1[2 ETHYL 6 OXOCYCLOHEXYL] 3 PHENYLPROPYL] 2 METHYLPROPANE 2 SULFINAMIDE; N TERT BUTYLSULFINYL IMINE; NAPHTHYL GROUP; PHOSPHORAMIDOUS ACID DERIVATIVE; SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; CONJUGATION; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; SYNTHESIS; X RAY ANALYSIS;

EID: 67650080762     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1216821     Document Type: Article

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