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Volumn 36, Issue 23, 1997, Pages 2620-2623

Highly enantioselective catalytic conjugate addition and tandem conjugate addition-aldol reactions of organozinc reagents

Author keywords

1,4 additions; Aldol reactions; Asymmetric synthesis; C C coupling; Homogeneous catalysis; Zinc

Indexed keywords


EID: 0031573812     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199726201     Document Type: Article
Times cited : (467)

References (35)
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    • Mismatched ligand S,S,S-1 afforded 4a with 82% yield and 75% ee; b the introduction of substituents at the 3,3′-positions of the binaphthol moiety only marginally affected the enantioselectivities
    • a) Mismatched ligand S,S,S-1 afforded 4a with 82% yield and 75% ee; b) the introduction of substituents at the 3,3′-positions of the binaphthol moiety only marginally affected the enantioselectivities.
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    • The spectral and analytical data for all new compounds were in agreement with the indicated structures
    • The spectral and analytical data for all new compounds were in agreement with the indicated structures.
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    • a) For a catalytic asymmetric tandem Michael-aldol reaction, see T. Arai, H. Sasai, K. Aoe, K. Okamura, T. Date, M. Shibasaki, Angew. Chem. 1996, 108, 103; Angew. Chem. Int. Ed. Engl. 1996, 35, 104; b) M. Kitamura, T. Miki, K. Nakano, R. Noyori, Tetrahedron Lett. 1996, 37, 5141.
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    • a) For a catalytic asymmetric tandem Michael-aldol reaction, see T. Arai, H. Sasai, K. Aoe, K. Okamura, T. Date, M. Shibasaki, Angew. Chem. 1996, 108, 103; Angew. Chem. Int. Ed. Engl. 1996, 35, 104; b) M. Kitamura, T. Miki, K. Nakano, R. Noyori, Tetrahedron Lett. 1996, 37, 5141.
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    • a) For a catalytic asymmetric tandem Michael-aldol reaction, see T. Arai, H. Sasai, K. Aoe, K. Okamura, T. Date, M. Shibasaki, Angew. Chem. 1996, 108, 103; Angew. Chem. Int. Ed. Engl. 1996, 35, 104; b) M. Kitamura, T. Miki, K. Nakano, R. Noyori, Tetrahedron Lett. 1996, 37, 5141.
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    • The X-ray structural analysis of compound 6b was performed by Dr. A. L. Spek (Utrecht University). Details will be reported separately
    • The X-ray structural analysis of compound 6b was performed by Dr. A. L. Spek (Utrecht University). Details will be reported separately.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.