An efficient synthesis of enantiomerically enriched trifluoromethylated 1,2-diols and 1,2-amino alcohols with quaternary stereocenters by diastereoselective addition of TMSCF3 to chiral 2-acyl-1,3- perhydrobenzoxazines

Journal of Organic Chemistry

Volumn 71, Issue 5, 2006, Pages 2177-2180

  Pedrosa, Rafael ^a   Sayalero, Sonia ^a,b   Vicente, Martina ^a   Maestro, Alicia ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

^b INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA ICIQ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,2-AMINO ALCOHOLS; CHIRAL 2-ACYL-1,3-PERHYDROBENZOXAZINES; DIASTEREOSELECTIVITY;

ALCOHOLS; AMINO ACIDS; PHASE TRANSITIONS;

SYNTHESIS (CHEMICAL);

1,3 PERHYDROBENZOXAZINE DERIVATIVE; AMINOALCOHOL; BENZOXAZINE DERIVATIVE; ORGANOFLUORINE DERIVATIVE; TRIFLUOROMETHYL 1,2 DIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ENANTIOMER; ENANTIOSELECTIVITY; FLUORINATION; METHYLATION; STEREOCHEMISTRY; SYNTHESIS;

AMINO ALCOHOLS; BENZOXAZINES; HYDROCARBONS, FLUORINATED; SILANES; STEREOISOMERISM;

EID: 33644653856     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo052458v     Document Type: Article

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