-
1
-
-
0029019660
-
BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts
-
Onizuka T, Moriyama M, Yamochi T, Kuroda T, Kazama A, Kanazawa N, Sato K, Kato T, Ota H, Mori S. BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts. Blood 1995;86:28-37.
-
(1995)
Blood
, vol.86
, pp. 28-37
-
-
Onizuka, T.1
Moriyama, M.2
Yamochi, T.3
Kuroda, T.4
Kazama, A.5
Kanazawa, N.6
Sato, K.7
Kato, T.8
Ota, H.9
Mori, S.10
-
2
-
-
0029045421
-
BCL-6 protein is expressed in germinal-center B cells
-
Cattoretti G, Chang CC, Cechova K, Zhang J, Ye BH, Falini B, Louie DC, Offit K, Chaganti RS, Dalla-Favera R. BCL-6 protein is expressed in germinal-center B cells. Blood 1995;86:45-53.
-
(1995)
Blood
, vol.86
, pp. 45-53
-
-
Cattoretti, G.1
Chang, C.C.2
Cechova, K.3
Zhang, J.4
Ye, B.H.5
Falini, B.6
Louie, D.C.7
Offit, K.8
Chaganti, R.S.9
Dalla-Favera, R.10
-
3
-
-
0029904294
-
BCL-6 expression during B-cell activation
-
Allman D, Jain A, Dent A, Maile RR, Selvaggi T, Kehry MR, Staudt LM. BCL-6 expression during B-cell activation. Blood 1996;87:5257-68.
-
(1996)
Blood
, vol.87
, pp. 5257-5268
-
-
Allman, D.1
Jain, A.2
Dent, A.3
Maile, R.R.4
Selvaggi, T.5
Kehry, M.R.6
Staudt, L.M.7
-
4
-
-
0030763072
-
Disruption of the Bcl6 gene results in an impaired germinal center formation
-
Fukuda T, Yoshida T, Okada S, Hatano M, Miki T, Ishibashi K, Okabe S, Koseki H, Hirosawa S, Taniguchi M, Miyasaka N, Tokuhisa T. Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med 1997;186:439-48.
-
(1997)
J Exp Med
, vol.186
, pp. 439-448
-
-
Fukuda, T.1
Yoshida, T.2
Okada, S.3
Hatano, M.4
Miki, T.5
Ishibashi, K.6
Okabe, S.7
Koseki, H.8
Hirosawa, S.9
Taniguchi, M.10
Miyasaka, N.11
Tokuhisa, T.12
-
5
-
-
0034278508
-
BCL-6 regulates chemokine gene transcription in macrophages
-
Toney LM, Cattoretti G, Graf JA, Merghoub T, Pandolfi PP, Dalla-Favera R, Ye BH, Dent AL. BCL-6 regulates chemokine gene transcription in macrophages. Nat Immunol 2000;1:214-20.
-
(2000)
Nat Immunol
, vol.1
, pp. 214-220
-
-
Toney, L.M.1
Cattoretti, G.2
Graf, J.A.3
Merghoub, T.4
Pandolfi, P.P.5
Dalla-Favera, R.6
Ye, B.H.7
Dent, A.L.8
-
6
-
-
0032773607
-
Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6
-
Staudt LM, Dent AL, Shaffer AL, Yu X. Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6. Int Rev Immunol 1999;18:381-403.
-
(1999)
Int Rev Immunol
, vol.18
, pp. 381-403
-
-
Staudt, L.M.1
Dent, A.L.2
Shaffer, A.L.3
Yu, X.4
-
7
-
-
0027495491
-
Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma
-
Ye BH, Lista F, Lo Coco F, Knowles DM, Offit K, Chaganti RS, Dalla-Favera R. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 1993;262:747-50.
-
(1993)
Science
, vol.262
, pp. 747-750
-
-
Ye, B.H.1
Lista, F.2
Lo Coco, F.3
Knowles, D.M.4
Offit, K.5
Chaganti, R.S.6
Dalla-Favera, R.7
-
8
-
-
0029562068
-
Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma
-
Ye BH, Chaganti S, Chang CC, Niu H, Corradini P, Chaganti RS, Dalla-Favera R. Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. EMBO J 1995;14:6209-17.
-
(1995)
EMBO J
, vol.14
, pp. 6209-6217
-
-
Ye, B.H.1
Chaganti, S.2
Chang, C.C.3
Niu, H.4
Corradini, P.5
Chaganti, R.S.6
Dalla-Favera, R.7
-
9
-
-
19344368745
-
Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice
-
Cattoretti G, Pasqualucci L, Ballon G, Tam W, Nandula SV, Shen Q, Mo T, Murty VV, Dalla-Favera R. Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice. Cancer Cell 2005;7:445-55.
-
(2005)
Cancer Cell
, vol.7
, pp. 445-455
-
-
Cattoretti, G.1
Pasqualucci, L.2
Ballon, G.3
Tam, W.4
Nandula, S.V.5
Shen, Q.6
Mo, T.7
Murty, V.V.8
Dalla-Favera, R.9
-
10
-
-
4644302712
-
The human BCL6 transgene promotes the development of lymphomas in the mouse
-
Baron BW, Anastasi J, Montag A, Huo D, Baron RM, Karrison T, Thirman MJ, Subudhi SK, Chin RK, Felsher DW, Fu YX, McKeithan TW, et al. The human BCL6 transgene promotes the development of lymphomas in the mouse. Proc Natl Acad Sci USA 2004;101:14198-203.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14198-14203
-
-
Baron, B.W.1
Anastasi, J.2
Montag, A.3
Huo, D.4
Baron, R.M.5
Karrison, T.6
Thirman, M.J.7
Subudhi, S.K.8
Chin, R.K.9
Felsher, D.W.10
Fu, Y.X.11
McKeithan, T.W.12
-
11
-
-
1242295365
-
Transcriptional repressor BCL-6 immortalizes germinal center-like B cells in the absence of p53 function
-
Kusam S, Vasanwala FH, Dent AL. Transcriptional repressor BCL-6 immortalizes germinal center-like B cells in the absence of p53 function. Oncogene 2004;23:839-44.
-
(2004)
Oncogene
, vol.23
, pp. 839-844
-
-
Kusam, S.1
Vasanwala, F.H.2
Dent, A.L.3
-
12
-
-
10344247666
-
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
-
Phan RT, Dalla-Favera R. The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 2004;432:635-9.
-
(2004)
Nature
, vol.432
, pp. 635-639
-
-
Phan, R.T.1
Dalla-Favera, R.2
-
13
-
-
20444502955
-
1 expression delineates heterogeneity in primary Th2 cells
-
Chang HC, Zhang S, Thieu VT, Slee RB, Bruns HA, Laribee RN, Klemsz MJ, Kaplan MH. PU.1 expression delineates heterogeneity in primary Th2 cells. Immunity 2005;22:693-703.
-
(2005)
Immunity
, vol.22
, pp. 693-703
-
-
Chang, H.C.1
Zhang, S.2
Thieu, V.T.3
Slee, R.B.4
Bruns, H.A.5
Laribee, R.N.6
Klemsz, M.J.7
Kaplan, M.P.8
-
14
-
-
32644434044
-
BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma
-
Margalit O, Amram H, Amariglio N, Simon AJ, Shaklai S, Granot G, Minsky N, Shimoni A, Harmelin A, Givol D, Shohat M, Oren M, et al. BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma. Blood 2006;107:1599-607.
-
(2006)
Blood
, vol.107
, pp. 1599-1607
-
-
Margalit, O.1
Amram, H.2
Amariglio, N.3
Simon, A.J.4
Shaklai, S.5
Granot, G.6
Minsky, N.7
Shimoni, A.8
Harmelin, A.9
Givol, D.10
Shohat, M.11
Oren, M.12
-
15
-
-
0031689601
-
Coexpression of CD40 and CD40 ligand in B-cell lymphoma cells
-
Clodi K, Asgary Z, Zhao S, Kliche KO, Cabanillas F, Andreeff M, Younes A. Coexpression of CD40 and CD40 ligand in B-cell lymphoma cells. Br J Haematol 1998;103:270-5.
-
(1998)
Br J Haematol
, vol.103
, pp. 270-275
-
-
Clodi, K.1
Asgary, Z.2
Zhao, S.3
Kliche, K.O.4
Cabanillas, F.5
Andreeff, M.6
Younes, A.7
-
16
-
-
0036173059
-
A CD40 signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas
-
Pham LV, Tamayo AT, Yoshimura LC, Lo P, Terry N, Reid PS, Ford RJ. A CD40 signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas. Immunity 2002;16:37-50.
-
(2002)
Immunity
, vol.16
, pp. 37-50
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lo, P.4
Terry, N.5
Reid, P.S.6
Ford, R.J.7
-
17
-
-
28444491798
-
Constitutive NF-kappaB and NFAT activation in aggressive B cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
-
Pham LV, Tamayo AT, Yoshimura LC, Lin-Lee YC, Ford RJ. Constitutive NF-kappaB and NFAT activation in aggressive B cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival. Blood 2005;106:3940-7.
-
(2005)
Blood
, vol.106
, pp. 3940-3947
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lin-Lee, Y.C.4
Ford, R.J.5
-
18
-
-
0034684672
-
Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6
-
Reljic R, Wagner SD, Peakman LJ, Fearon DT. Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6. J Exp Med 2000;192:1841-8.
-
(2000)
J Exp Med
, vol.192
, pp. 1841-1848
-
-
Reljic, R.1
Wagner, S.D.2
Peakman, L.J.3
Fearon, D.T.4
-
19
-
-
0033680860
-
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
-
Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 2000;13:199-212.
-
(2000)
Immunity
, vol.13
, pp. 199-212
-
-
Shaffer, A.L.1
Yu, X.2
He, Y.3
Boldrick, J.4
Chan, E.P.5
Staudt, L.M.6
-
20
-
-
18444395232
-
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
-
Shaffer AL, Lin KI, Kuo TC, Yu X, Hurt EM, Rosenwald A, Giltnane JM, Yang L, Zhao H, Calame K, Staudt LM. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 2002;17:51-62.
-
(2002)
Immunity
, vol.17
, pp. 51-62
-
-
Shaffer, A.L.1
Lin, K.I.2
Kuo, T.C.3
Yu, X.4
Hurt, E.M.5
Rosenwald, A.6
Giltnane, J.M.7
Yang, L.8
Zhao, H.9
Calame, K.10
Staudt, L.M.11
-
21
-
-
0142219442
-
Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells
-
Shapiro-Shelef M, Lin KI, McHeyzer-Williams LJ, Liao J, McHeyzer-Williams MG, Calame K. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity 2003;19:607-20.
-
(2003)
Immunity
, vol.19
, pp. 607-620
-
-
Shapiro-Shelef, M.1
Lin, K.I.2
McHeyzer-Williams, L.J.3
Liao, J.4
McHeyzer-Williams, M.G.5
Calame, K.6
-
22
-
-
27144462049
-
BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
-
Phan RT, Saito M, Basso K, Niu H, Dalla-Favera R. BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells. Nat Immunol 2005;6:1054-60.
-
(2005)
Nat Immunol
, vol.6
, pp. 1054-1060
-
-
Phan, R.T.1
Saito, M.2
Basso, K.3
Niu, H.4
Dalla-Favera, R.5
-
23
-
-
18344389897
-
The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: Implications for a role of BCL6 in the down-regulation of apoptosis
-
Baron BW, Anastasi J, Thirman MJ, Furukawa Y, Fears S, Kim DC, Simone F, Birkenbach M, Montag A, Sadhu A, Zeleznik-Le N, McKeithan TW. The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis. Proc Natl Acad Sci USA 2002;99:2860-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2860-2865
-
-
Baron, B.W.1
Anastasi, J.2
Thirman, M.J.3
Furukawa, Y.4
Fears, S.5
Kim, D.C.6
Simone, F.7
Birkenbach, M.8
Montag, A.9
Sadhu, A.10
Zeleznik-Le, N.11
McKeithan, T.W.12
-
24
-
-
0037134491
-
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor
-
Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA. The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor. J Biol Chem 2002;277:14255-65.
-
(2002)
J Biol Chem
, vol.277
, pp. 14255-14265
-
-
Tang, T.T.1
Dowbenko, D.2
Jackson, A.3
Toney, L.4
Lewin, D.A.5
Dent, A.L.6
Lasky, L.A.7
-
25
-
-
34250762588
-
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR
-
Ranuncolo SM, Polo JM, Dierov J, Singer M, Kuo T, Greally J, Green R, Carroll M, Melnick A. Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. Nat Immunol 2007;8:705-14.
-
(2007)
Nat Immunol
, vol.8
, pp. 705-714
-
-
Ranuncolo, S.M.1
Polo, J.M.2
Dierov, J.3
Singer, M.4
Kuo, T.5
Greally, J.6
Green, R.7
Carroll, M.8
Melnick, A.9
-
26
-
-
53049097048
-
BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner
-
Ranuncolo SM, Wang L, Polo JM, Dell'Oso T, Dierov J, Gaymes TJ, Rassool F, Carroll M, Melnick A. BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner. J Biol Chem 2008;283:22565-72.
-
(2008)
J Biol Chem
, vol.283
, pp. 22565-22572
-
-
Ranuncolo, S.M.1
Wang, L.2
Polo, J.M.3
Dell'Oso, T.4
Dierov, J.5
Gaymes, T.J.6
Rassool, F.7
Carroll, M.8
Melnick, A.9
-
27
-
-
50949097945
-
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells
-
Polo JM, Ci W, Licht JD, Melnick A. Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells. Blood 2008;112:644-51.
-
(2008)
Blood
, vol.112
, pp. 644-651
-
-
Polo, J.M.1
Ci, W.2
Licht, J.D.3
Melnick, A.4
-
28
-
-
34548237299
-
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
-
Saito M, Gao J, Basso K, Kitagawa Y, Smith PM, Bhagat G, Pernis A, Pasqualucci L, Dalla-Favera R. A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 2007;12:280-92.
-
(2007)
Cancer Cell
, vol.12
, pp. 280-292
-
-
Saito, M.1
Gao, J.2
Basso, K.3
Kitagawa, Y.4
Smith, P.M.5
Bhagat, G.6
Pernis, A.7
Pasqualucci, L.8
Dalla-Favera, R.9
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