메뉴 건너뛰기




Volumn 29, Issue 14, 2009, Pages 3929-3940

The ability of GAP1IP4BP to function as a Rap1 GTPase-activating protein (GAP) requires its Ras GAP-related domain and an arginine finger rather than an asparagine thumb

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; GAP1 PROTEIN; GLUTAMINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAP1 PROTEIN; UNCLASSIFIED DRUG; CELL RECEPTOR; HYBRID PROTEIN; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE RECEPTOR; INOSITOL-1,3,4,5-TETRAKISPHOSPHATE RECEPTOR; PRIMER DNA; RAP1GAP PROTEIN, HUMAN;

EID: 67650065262     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00427-09     Document Type: Article
Times cited : (24)

References (41)
  • 1
    • 0031231083 scopus 로고    scopus 로고
    • Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras
    • Ahmadian, M. R., P. Stege, K. Scheffzek, and A. Wittinghofer. 1997. Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras. Nat. Struct. Biol. 4:686-689.
    • (1997) Nat. Struct. Biol , vol.4 , pp. 686-689
    • Ahmadian, M.R.1    Stege, P.2    Scheffzek, K.3    Wittinghofer, A.4
  • 2
    • 0032544675 scopus 로고    scopus 로고
    • Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog
    • Allen, M., S. Chu, S. Brill, C. Stotler, and A. Buckler. 1998. Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog. Gene 218:17-25.
    • (1998) Gene , vol.218 , pp. 17-25
    • Allen, M.1    Chu, S.2    Brill, S.3    Stotler, C.4    Buckler, A.5
  • 3
    • 0025201012 scopus 로고
    • The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
    • Ballester, R., D. Marchuk, M. Boguski, A. Saulino, R. Letcher, M. Wigler, and F. Collins. 1990. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 63:851-859.
    • (1990) Cell , vol.63 , pp. 851-859
    • Ballester, R.1    Marchuk, D.2    Boguski, M.3    Saulino, A.4    Letcher, R.5    Wigler, M.6    Collins, F.7
  • 4
    • 0037451803 scopus 로고    scopus 로고
    • GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
    • Bernards, A. 2003. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim. Biophys. Acta 1603:47-82.
    • (2003) Biochim. Biophys. Acta , vol.1603 , pp. 47-82
    • Bernards, A.1
  • 5
    • 3042796979 scopus 로고    scopus 로고
    • GAP control: Regulating the regulators of small GTPases
    • Bernards, A., and J. Settleman. 2004. GAP control: regulating the regulators of small GTPases. Trends Cell Biol. 14:377-385.
    • (2004) Trends Cell Biol , vol.14 , pp. 377-385
    • Bernards, A.1    Settleman, J.2
  • 9
    • 8544261164 scopus 로고    scopus 로고
    • Fourier transform infrared spectroscopy on the Rap·RapGAP reaction, GTPase activation without an arginine finger
    • Chakrabarti, P. P., Y. Suveyzdis, A. Wittinghofer, and K. Gerwert. 2004. Fourier transform infrared spectroscopy on the Rap·RapGAP reaction, GTPase activation without an arginine finger. J. Biol. Chem. 279:46226-46233.
    • (2004) J. Biol. Chem , vol.279 , pp. 46226-46233
    • Chakrabarti, P.P.1    Suveyzdis, Y.2    Wittinghofer, A.3    Gerwert, K.4
  • 10
    • 0032078872 scopus 로고    scopus 로고
    • A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II
    • Chen, H. J., M. Rojas-Soto, A. Oguni, and M. B. Kennedy. 1998. A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II. Neuron 20:895-904.
    • (1998) Neuron , vol.20 , pp. 895-904
    • Chen, H.J.1    Rojas-Soto, M.2    Oguni, A.3    Kennedy, M.B.4
  • 11
    • 0027170176 scopus 로고
    • RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts
    • Cook, S. J., B. Rubinfeld, I. Albert, and F. McCormick. 1993. RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts. EMBO J. 12:3475-3485.
    • (1993) EMBO J , vol.12 , pp. 3475-3485
    • Cook, S.J.1    Rubinfeld, B.2    Albert, I.3    McCormick, F.4
  • 13
    • 0029112873 scopus 로고
    • Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family
    • Cullen, P. J., J. J. Hsuan, O. Truong, A. J. Letcher, T. R. Jackson, A. P. Dawson, and R. F. Irvine. 1995. Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family. Nature 376:527-530.
    • (1995) Nature , vol.376 , pp. 527-530
    • Cullen, P.J.1    Hsuan, J.J.2    Truong, O.3    Letcher, A.J.4    Jackson, T.R.5    Dawson, A.P.6    Irvine, R.F.7
  • 14
    • 0036274818 scopus 로고    scopus 로고
    • Integration of calcium and Ras signalling
    • Cullen, P. J., and P. J. Lockyer. 2002. Integration of calcium and Ras signalling. Nat. Rev. Mol. Cell Biol. 3:339-348.
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 339-348
    • Cullen, P.J.1    Lockyer, P.J.2
  • 15
  • 16
    • 0032952586 scopus 로고    scopus 로고
    • The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation
    • Gao, Q., S. Srinivasan, S. N. Boyer, D. E. Wazer, and V. Band. 1999. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. Mol. Cell. Biol. 19:733-744.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 733-744
    • Gao, Q.1    Srinivasan, S.2    Boyer, S.N.3    Wazer, D.E.4    Band, V.5
  • 17
    • 0028947758 scopus 로고
    • Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression
    • Hattori, M., N. Tsukamoto, M. S. Nue-e-Kamal, B. Rubinfeld, K. Iwai, H. Kubota, H. Maruta, and N. Minato. 1995. Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression. Mol. Cell. Biol. 15:552-560.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 552-560
    • Hattori, M.1    Tsukamoto, N.2    Nue-e-Kamal, M.S.3    Rubinfeld, B.4    Iwai, K.5    Kubota, H.6    Maruta, H.7    Minato, N.8
  • 18
    • 0032055396 scopus 로고    scopus 로고
    • SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
    • Kim, J. H., D. Liao, L. F. Lau, and R. L. Huganir. 1998. SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20:683-691.
    • (1998) Neuron , vol.20 , pp. 683-691
    • Kim, J.H.1    Liao, D.2    Lau, L.F.3    Huganir, R.L.4
  • 19
    • 0024600222 scopus 로고
    • A ras-related gene with transformation suppressor activity
    • Kitayama, H., Y. Sugimoto, T. Matsuzaki, Y. Ikawa, and M. Noda. 1989. A ras-related gene with transformation suppressor activity. Cell 56:77-84.
    • (1989) Cell , vol.56 , pp. 77-84
    • Kitayama, H.1    Sugimoto, Y.2    Matsuzaki, T.3    Ikawa, Y.4    Noda, M.5
  • 20
    • 33846847701 scopus 로고    scopus 로고
    • Rap1: A key regulator in cell-cell junction formation
    • Kooistra, M. R. H., N. Dubé, and J. L. Bos. 2007. Rap1: a key regulator in cell-cell junction formation. J. Cell Sci. 120:17-22.
    • (2007) J. Cell Sci , vol.120 , pp. 17-22
    • Kooistra, M.R.H.1    Dubé, N.2    Bos, J.L.3
  • 21
    • 4143133173 scopus 로고    scopus 로고
    • SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation
    • Krapivinsky, G., I. Medina, I. Krapivinsky, S. Gapon, and D. E. Clapham. 2004. SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation. Neuron 43:563-574.
    • (2004) Neuron , vol.43 , pp. 563-574
    • Krapivinsky, G.1    Medina, I.2    Krapivinsky, I.3    Gapon, S.4    Clapham, D.E.5
  • 26
    • 0347716759 scopus 로고    scopus 로고
    • Rheb fills a GAP between TSC and TOR
    • Manning, B. D., and L. C. Cantley. 2003. Rheb fills a GAP between TSC and TOR. Trends Biochem. Sci. 28:573-576.
    • (2003) Trends Biochem. Sci , vol.28 , pp. 573-576
    • Manning, B.D.1    Cantley, L.C.2
  • 28
    • 22744445886 scopus 로고    scopus 로고
    • Mitin, N., K. L. Rossman, and C. J. Der. 2005. Signaling interplay in Ras superfamily function. Curr. Biol. 15:R563-R574.
    • Mitin, N., K. L. Rossman, and C. J. Der. 2005. Signaling interplay in Ras superfamily function. Curr. Biol. 15:R563-R574.
  • 29
    • 3843065433 scopus 로고    scopus 로고
    • The semaphorin 4D receptor plexin-B1 is a GTPase activating protein for R-Ras
    • Oinuma, I., Y. Ishikawa, H. Katoh, and M. Negishi. 2004. The semaphorin 4D receptor plexin-B1 is a GTPase activating protein for R-Ras. Science 305:862-865.
    • (2004) Science , vol.305 , pp. 862-865
    • Oinuma, I.1    Ishikawa, Y.2    Katoh, H.3    Negishi, M.4
  • 34
    • 0029829561 scopus 로고    scopus 로고
    • Scheffzek, K., A. Lautwein, W. Kabsch, M. R. Ahmadian, and A. Wittinghofer. 1996. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature 384:591-596.
    • Scheffzek, K., A. Lautwein, W. Kabsch, M. R. Ahmadian, and A. Wittinghofer. 1996. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature 384:591-596.
  • 35
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert, S., K. Shannon, and G. Bollag. 2007. Hyperactive Ras in developmental disorders and cancer. Nat. Rev. Cancer 7:295-308.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 36
    • 41949114173 scopus 로고    scopus 로고
    • The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues
    • Scrima, A., C. Thomas, D. Deaconescu, and A. Wittinghofer. 2008. The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues. EMBO J. 27:1145-1153.
    • (2008) EMBO J , vol.27 , pp. 1145-1153
    • Scrima, A.1    Thomas, C.2    Deaconescu, D.3    Wittinghofer, A.4
  • 37
    • 0038741814 scopus 로고    scopus 로고
    • Does Rap1 deserve a bad Rap?
    • Stork, P. J. 2003. Does Rap1 deserve a bad Rap? Trends Biochem. Sci. 28:267-275.
    • (2003) Trends Biochem. Sci , vol.28 , pp. 267-275
    • Stork, P.J.1
  • 39
    • 0037066783 scopus 로고    scopus 로고
    • The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2
    • Wang, Z., C. P. Tseng, R. C. Pong, H. Chen, J. D. McConnell, N. Navone, and J. T. Hsieh. 2002. The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2. J. Biol. Chem. 277:12622-12631.
    • (2002) J. Biol. Chem , vol.277 , pp. 12622-12631
    • Wang, Z.1    Tseng, C.P.2    Pong, R.C.3    Chen, H.4    McConnell, J.D.5    Navone, N.6    Hsieh, J.T.7
  • 40
    • 0025244911 scopus 로고
    • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
    • Xu, G. F., B. Lin, K. Tanaka, D. Dunn, D. Wood, R. Gesteland, R. White, R. Weiss, and F. Tamanoi. 1990. The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae. Cell 63:835-841.
    • (1990) Cell , vol.63 , pp. 835-841
    • Xu, G.F.1    Lin, B.2    Tanaka, K.3    Dunn, D.4    Wood, D.5    Gesteland, R.6    White, R.7    Weiss, R.8    Tamanoi, F.9
  • 41
    • 33751264910 scopus 로고    scopus 로고
    • The GAP1 family of GTPase-activating proteins: Spatial and temporal regulators of small GTPase signalling
    • Yarwood, S., D. Bouyoucef-Cherchalli, P. J. Cullen, and S. Kupzig. 2006. The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling. Biochem. Soc. Trans. 34:846-850.
    • (2006) Biochem. Soc. Trans , vol.34 , pp. 846-850
    • Yarwood, S.1    Bouyoucef-Cherchalli, D.2    Cullen, P.J.3    Kupzig, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.