Delineating bacteriostatic and bactericidal targets in mycobacteria using IPTG inducible antisense expression

PLoS ONE

Volumn 4, Issue 6, 2009, Pages

  Kaur, Parvinder ^a   Agarwal, Saurabh ^a,b   Datta, Santanu ^a  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA GALACTOSIDASE; COMPLEMENTARY RNA; ETHAMBUTOL; FTSZ PROTEIN; ISOLEUCINE; ISONIAZID; ISOPROPYL THIOGALACTOSIDE; LEUCINE; MESSENGER RNA; NUCLEOTIDYLTRANSFERASE; PANTOTHENIC ACID; PROTEIN EMBB; PROTEIN ILVB; PROTEIN INHA; PROTEIN RPLJ; PROTEIN RPOC; PROTEIN RPSL; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIBOSOME RNA; RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT; UNCLASSIFIED DRUG; VALINE; ANTIINFECTIVE AGENT; ANTISENSE OLIGONUCLEOTIDE; QUINOLONE DERIVATIVE; REPRESSOR PROTEIN; TUBERCULOSTATIC AGENT;

ANTISENSE VECTOR; ARTICLE; BACTERIAL GENE; BACTERIAL KINETICS; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; EXPRESSION VECTOR; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE REPRESSION; GENETIC VARIABILITY; GROWTH INHIBITION; MYCOBACTERIUM; NONHUMAN; CHEMISTRY; DRUG EFFECT; KINETICS; METABOLISM; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; PLASMID;

BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE;

ANTI-BACTERIAL AGENTS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CLONING, MOLECULAR; FLUOROQUINOLONES; GENE EXPRESSION REGULATION, BACTERIAL; ISONIAZID; ISOPROPYL THIOGALACTOSIDE; KINETICS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; OLIGONUCLEOTIDES, ANTISENSE; PLASMIDS; REPRESSOR PROTEINS; RIFAMPIN;

EID: 67650046677     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005923     Document Type: Article

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