Effects of cranberry juice on pharmacokinetics of β-lactam antibiotics following oral administration

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 7, 2009, Pages 2725-2732

  Li, Meng ^a   Andrew, Marilee A ^a,b   Wang, Joanne ^a   Salinger, David H ^b   Vicini, Paolo ^b   Grady, Richard W ^c   Phillips, Brian ^d   Shen, Danny D ^a,d   Anderson, Gail D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CEFACLOR;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRANBERRY JUICE; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG CLEARANCE; FEMALE; FOOD DRUG INTERACTION; HUMAN; HUMAN EXPERIMENT; KIDNEY CLEARANCE; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE;

ADMINISTRATION, ORAL; ADULT; AMOXICILLIN; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; BEVERAGES; CEFACLOR; DRUG INTERACTIONS; FEMALE; HUMANS; VACCINIUM MACROCARPON; YOUNG ADULT;

EID: 67649978676     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00774-08     Document Type: Article

References (39)

1. Albert, X., I. Huertas, I. I. Pereiro, J. Sanfelix, V. Gosalbes, and C. Perrota. 2004. Antibiotics for preventing recurrent urinary tract infection in nonpregnant women. Cochrane Database Syst. Rev. 3:CD001209. doi:10.1002/14651858.CD001209.pub2.
2. Andrew, M. A., T. R. Easterling, D. B. Carr, D. Shen, M. L. Buchanan, T. Rutherford, R. Bennett, P. Vicini, and M. F. Hebert. 2007. Amoxicillin pharmacokinetics in pregnant women: modeling and simulations of dosage strategies. Clin. Pharmacol. Ther. 81:547-556.
3. Avorn, J., M. Monane, J. H. Gurwitz, R. J. Glynn, I. Choodnovskiy, and L. A. Lipsitz. 1994. Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA 271:751-754.
4. Chen, H., Y. Zuo, and Y. Deng. 2001. Separation and determination of flavonoids and other phenolic compounds in cranberry juice by high-performance liquid chromatography. J. Chromatogr. A 913:387-395.
5. Deguchi, T., H. Kusuhara, A. Takadate, H. Endou, M. Otagiri, and Y. Sugiyama. 2004. Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney Int. 65:162-174.
6. Dresser, G. K., and D. G. Bailey. 2003. The effects of fruit juices on drug disposition: a new model for drug interactions. Eur. J. Clin. Investig. 33(Suppl. 2):10-16.
7. Dresser, G. K., D. G. Bailey, B. F. Leake, U. I. Schwarz, P. A. Dawson, D. J. Freeman, and R. B. Kim. 2002. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther. 71:11-20.
8. Grant, P. 2004. Warfarin and cranberry juice: an interaction? J. Heart Valve Dis. 13:25-26.
9. Greenblatt, D. J., L. L. von Moltke, E. S. Perloff, Y. Luo, J. S. Harmatz, and M. A. Zinny. 2006. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin. Pharmacol. Ther. 79:125-133.
10. Griebling, T. L. 2005. Urologic diseases in America project: trends in resource use for urinary tract infections in men. J. Urol. 173:1288-1294.
11. Griebling, T. L. 2005. Urologic diseases in America project: trends in resource use for urinary tract infections in women. J. Urol. 173:1281-1287.
12. Griffiths, A. P., A. Beddall, and S. Pegler. 2008. Fatal haemopericardium and gastrointestinal haemorrhage due to possible interaction of cranberry juice with warfarin. J. R. Soc. Health 128:324-326.
13. Griffiths, P. 2003. The role of cranberry juice in the treatment of urinary tract infections. Br. J. Community Nurs. 8:557-561.
14. Howell, A. B., N. Vorsa, A. Der Marderosian, and L. Y. Foo. 1998. Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries. N. Engl. J. Med. 339: 1085-1086.
15. Hukkanen, J., P. Jacob III, and N. L. Benowitz. 2006. Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance. Clin. Pharmacol. Ther. 80:522-530.
16. Kontiokari, T., K. Sundqvist, M. Nuutinen, T. Pokka, M. Koskela, and M. Uhari. 2001. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ 322:1571.
17. Krahenbuhl, L., J. Reichen, C. Talos, and S. Krahenbuhl. 1997. Benzoic acid metabolism reflects hepatic mitochondrial function in rats with long-term extrahepatic cholestasis. Hepatology 25:278-283.
18. Lang, T. T., J. D. Young, and C. E. Cass. 2004. Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line. Mol. Pharmacol. 65:925-933.
19. Li, M., G. D. Anderson, B. R. Phillips, W. Kong, D. D. Shen, and J. Wang. 2006. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab. Dispos. 34:547-555.
20. Lilja, J. J., J. T. Backman, and P. J. Neuvonen. 2007. Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam-probes of CYP2C9, CYP1A2, and CYP3A4. Clin. Pharmacol. Ther. 81:833-839.
21. Lilja, J. J., L. Juntti-Patinen, and P. J. Neuvonen. 2004. Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol. Clin. Pharmacol. Ther. 75:184-190.
22. Meyers, B. R. 2000. Cefaclor revisited. Clin. Ther. 22:154-166.
23. Paeng, C. H., M. Sprague, and C. A. Jackevicius. 2007. Interaction between warfarin and cranberry juice. Clin. Ther. 29:1730-1735.
24. Rahn, D. D. 2008. Urinary tract infections: contemporary management. Urol. Nurs. 28:333-341.
25. Raz, R., B. Chazan, and M. Dan. 2004. Cranberry juice and urinary tract infection. Clin. Infect. Dis. 38:1413-1419.
26. Rengelshausen, J., H. Lindenmaier, T. Cihlar, I. Walter-Sack, W. E. Haefeli, and J. Weiss. 2004. Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthine. Biochem. Biophys. Res. Commun. 320:90-94.
27. Rindone, J. P., and T. W. Murphy. 2006. Warfarin-cranberry juice interaction resulting in profound hypoprothrombinemia and bleeding. Am. J. Ther. 13:283-284.
28. Schooff, M., and K. Hill. 2005. Antibiotics for recurrent urinary tract infections. Am. Fam. Physician 71:1301-1302.
29. Schwarz, U. I., D. Seemann, R. Oertel, S. Miehlke, E. Kuhlisch, M. F. Fromm, R. B. Kim, D. G. Bailey, and W. Kirch. 2005. Grapefruit juice ingestion significantly reduces talinolol bioavailability. Clin. Pharmacol. Ther. 77:291-301.
30. Sinko, P., and G. L. Amidon. 1988. Characterization of the oral absorption of beta-lactam antibiotics. I. Cephalosporins: determination of intrinsic membrane absorption parameters in the rat intestine in situ. Pharm. Res. 5:645-650.
31. Stothers, L. 2002. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can. J. Urol. 9:1558-1562.
32. Suvarna, R., M. Pirmohamed, and L. Henderson. 2003. Possible interaction between warfarin and cranberry juice. BMJ 327:1454.
33. Sylvan, L., and N. P. Justice. 2005. Possible interaction between warfarin and cranberry juice. Am. Fam. Physician 72:1000.
34. Uesawa, Y., and K. Mohri. 2006. Effects of cranberry juice on nifedipine pharmacokinetics in rats. J. Pharm. Pharmacol. 58:1067-1072.
35. Walle, T. 2004. Absorption and metabolism of flavonoids. Free Radic. Biol. Med. 36:829-837.
36. Weisz, D., J. A. Seabrook, and R. K. Lim. 30 August 2008. Urinary nitrites is a significant predictor of pediatric UTI susceptibility to first- and thirdgeneration cephalosporins. J. Emerg. Med. [Epub ahead of print.]
37. White, C. T., and D. G. Matsell. 2001. Children's UTIs in the new millennium. Diagnosis, investigation, and treatment of childhood urinary tract infections in the year 2001. Can. Fam. Physician 47:1603-1608.
38. Wing, D. A., P. J. Rumney, C. W. Preslicka, and J. H. Chung. 2008. Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: a randomized, controlled pilot study. J. Urol. 180:1367-1372.
39. Zarowny, D., R. Ogilvie, D. Tamblyn, C. MacLeod, and J. Ruedy. 1974. Pharmacokinetics of amoxicillin. Clin. Pharmacol. Ther. 16:1045-1051.