Effects of cranberry juice on nifedipine pharmacokinetics in rats

Journal of Pharmacy and Pharmacology

Volumn 58, Issue 8, 2006, Pages 1067-1072

  Uesawa, Yoshihiro ^a   Mohri, Kiminori ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6',7' DIHYDROXYBERGAMOTTIN; BERGAMOTTIN; BERGAPTOL; CYTOCHROME P450 3A; FUROCOUMARIN DERIVATIVE; NIFEDIPINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRANBERRY JUICE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; FOOD DRUG INTERACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INCUBATION TIME; LIVER MICROSOME; MALE; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; RAT; SMALL INTESTINE;

ANIMALS; BEVERAGES; CALCIUM CHANNEL BLOCKERS; DRUG INTERACTIONS; FOOD-DRUG INTERACTIONS; HUMANS; INTESTINES; MALE; MICROSOMES; MICROSOMES, LIVER; NIFEDIPINE; OXIDATION-REDUCTION; PSORALENS; RATS; RATS, WISTAR; VACCINIUM MACROCARPON;

EID: 33747058281     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.58.8.0007     Document Type: Article

References (36)

1. Avorn, J., Monane, M., Gurwitz, J. H., Glynn, R. J., Choodnovskiy, I., Lipsitz, L. A. (1994) Reduction of bacteriuria and pyuria after ingestion of cranberry juice. J A M A 271: 751-754
2. Bailey, D. G., Spence, J. D., Edgar, B., Bayliff, C. D., Arnold, J. M. (1989) Ethanol enhances the hemodynamic effects of felodipine. Clin. Invest. Med. 12: 357-362
3. Bailey, D. G., Malcolm, J., Arnold, O., Spence, J. D. (1998) Grapefruit juice-drug interactions. Br. J. Clin. Pharmacol. 46: 101-110
4. Brunner, L. J., Munar, M. Y., Vallian, J., Wolfson, M., Stennett, D. J., Meyer, M. M., Bennett, W. M. (1998) Interaction between cyclosporine and grapefruit juice requires long-term ingestion in stable renal transplant recipients. Pharmacotherapy 18: 23-29
5. Burger, O., Ofek, I., Tabak, M., Weiss, E. I., Sharon, N., Neeman, I. (2000) A high molecular mass constituent of cranberry juice inhibits helicobacter pylori adhesion to human gastric mucus. F E M S Immunol. Med. Microbiol. 29: 295-301
6. Di Marco, M. P., Edwards, D. J., Wainer, I. W., Ducharme, M. P. (2002) The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein. Life Sci. 71: 1149-1160
7. Edwards, D. J., Fitzsimmons, M. E., Schuetz, E. G., Yasuda, K., Ducharme, M. P., Warbasse, L. H., Woster, P. M., Schuetz, J. D., Watkins, P. (1999) 6′,7′-Dihydroxybergamottin in grapefruit juice and seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein. Clin. Pharmacol. Ther. 65: 237-244
8. Egashira, K., Fukuda, E., Onga, T., Yogi, Y., Matsuya, F., Koyabu, N., Ohtani, H., Sawada, Y. (2003) Pomelo-induced increase in the blood level of tacrolimus in a renal transplant patient. Transplantation 75: 1057
9. Fitzsimmons, M. E., Collins, J. M. (1997) Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism. Drug Metab. Dispos. 25: 256-266
10. Foxman, B., Geiger, A. M., Palin, K., Gillespie, B., Koopman, J. S. (1995) First-time urinary tract infection and sexual behavior. Epidemiology 6: 162-168
11. Fromm, M. F. (2002) Genetically determined differences in P-glycoprotein function. Toxicology 27: 181-182, 299-303
12. Grant, P. (2004) Warfarin and cranberry juice: an interaction? J. Heart. Valve. Dis. 13: 25-26
13. Greenblatt, D. J., von Moltke, L. L., Perloff, E. S., Luo, Y., Harmatz, J. S., Zinny, M. A. (2006) Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin. Pharmacol. Ther. 79: 125-133
14. Grenier, J., Fradette, C., Morelli, G., Merritt, G. J., Vranderick, M., Ducharme, M. P. (2006) Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans. Clin. Pharmacol. Ther. 79: 255-262
15. Guo, L. Q., Yamazoe, Y. (2004) Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines. Acta Pharmacol. Sin. 25: 129-136
16. He, K., Iyer, K. R., Hayes, R. N., Sinz, M. W., Woolf, T. F., Hollenberg, P. F. (1998) Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice. Chem. Res. Toxicol. 11: 252-259
17. Hidaka, M., Okumura, M., Fujita, K., Ogikubo, T., Yamasaki, K., Iwakiri, T., Setoguchi, N., Arimori, K. (2005) Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab. Dispos. 33: 644-648
18. Kim, H., Yoon, Y. J., Shon, J. H., Cha, I. J., Shin, J. G., Liu, K. H. (2006) Inhibitory effects of fruit juices on cytochrome P450 3A (CYP3A) activity. Drug Metab. Dispos. (in press)
19. Koenigs, L. L., Trager, W. F. (1998) Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins. Biochemistry 37: 13184-13193
20. Kolars, J. C., Schmiedlin-Ren, P., Schuetz, J. D., Fang, C., Watkins, P. B. (1992) Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J. Clin. Invest. 90: 1871-1878
21. Liu, X., Xiao, G., Chen, W., Xu, Y., Wu, J. (2004) Quantification and purification of mulberry anthocyanins with macroporous resins. J. Biomed. Biotechnol. 2004: 326-331
22. Lown, K. S., Bailey, D. G., Fontana, R. J., Janardan, S. K., Adair, C. H., Fortlage, L. A., Brown, M. B., Guo, W., Watkins, P. B. (1997) Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. J. Clin. Invest. 99: 2545-2553
23. Matsubara, T., Kim, H. J., Miyata, M., Shimada, M., Nagata, K., Yamazoe, Y. (2004) Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat. J. Pharmacol. Exp. Ther. 309: 1282-1290
24. Mohri, K., Uesawa, Y. (2001a) Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures. Pharm. Res. 18: 1232-1236
25. Mohri, K., Uesawa, Y. (2001b) Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats. Pharm. Res. 18: 177-182
26. Mohri, K., Uesawa, Y., Sagawa, K. (2000) Effects of long-term grapefruit juice ingestion on nifedipine pharmacokinetics: induction of rat hepatic P-450 by grapefruit juice. Drug Metab. Dispos. 28: 482-486
27. Sagir, A., Schmitt, M., Dilger, K., Haussinger, D. (2003) Inhibition of cytochrome P450 3A: relevant drug interactions in gastroenterology. Digestion 68: 41-48
28. Seeram, N. P., Adams, L. S., Hardy, M. L., Heber, D. (2004) Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines. J. Agric. Food Chem. 52: 2512-2517
29. Soldner, A., Christians, U., Susanto, M., Wacher, V. J., Silverman, J. A., Benet, L. Z. (1999) Grapefruit juice activates P-glycoprotein-mediated drug transport. Pharm. Res. 16: 478-485
30. Suvarna, R., Pirmohamed, M., Henderson, L. (2003) Possible interaction between warfarin and cranberry juice. B M J 327: 1454
31. Takanaga, H., Ohnishi, A., Matsuo, H., Sawada, Y. (1998) Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells. Biol. Pharm. Bull. 21: 1062-1066
32. Uesawa, Y., Mohri, K. (2005a) Comprehensive determination of furanocoumarin derivatives in citrus juice by high performance liquid chromatography. Yakugaku Zasshi 125: 875-879
33. Uesawa, Y., Mohri, K. (2005b) Effects of sweetie juice on nifedipine pharmacokinetics in rats. Yakugaku Zasshi 125: 889-893
34. Weiss, E. I., Houri-Haddad, Y., Greenbaum, E., Hochman, N., Ofek, i., Zakay-Rones, Z. (2005) Cranberry juice constituents affect influenza virus adhesion and infectivity. Antiviral Res. 66: 9-12
35. Yamaoka, K., Nakagawa, T. (1983) A nonlinear least squares program based on differential equations, MULTI (RUNGE), for microcomputers. J. Pharmacobiodyn. 6: 595-606
36. Zhang, L., Ma, J., Pan, K., Go, V. L., Chen, J., You, W. C. (2005) Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter 10: 139-145