Quantitation of imidazo[1,2-a]quinoxaline derivatives in human and rat plasma using LC/ESI-MS

Journal of Separation Science

Volumn 32, Issue 9, 2009, Pages 1363-1373

  Khier, Sonia ^a   Moarbess, Georges ^a   Deleuze Masquefa, Carine ^a   Solassol, Isabelle ^b   Margout, Delphine ^a   Pinguet, Frédéric ^b   Bonnet, Pierre Antoine ^a   Bressolle, Françoise M M ^a  

^a UNIV MONTPELLIER   (France)

^b Department of Oncopharmacology   (France)

Author keywords

ESI MS; Human and rat matrices; Imidazo 1,2 a quinoxaline; LC; Lymphoma; Melanoma

Indexed keywords

ESI-MS; HUMAN AND RAT MATRICES; IMIDAZO[1,2-A]QUINOXALINE; LC; LYMPHOMA; MELANOMA;

CELL CULTURE; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; PLASMA (HUMAN);

PLASMAS;

1 (3 HYDROXYPHENYL) N METHYLIMIDAZO[1,2 A]QUINOXALIN 4 AMINE; 1 (3 METHOXYPHENYL) N METHYLIMIDAZO[1,2 A]QUINOXALIN 4 AMINE; EAPB 0503; EAPB 0603; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD TOXICITY; CALIBRATION; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG FATALITY; DRUG PURITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; IMIDAZOLES; MOLECULAR STRUCTURE; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

RATTUS;

EID: 67649973448     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200800668     Document Type: Article

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