Effect of varying chain length between P1 and P1′ position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4364-4366

  Chaudhary, Snehlata ^a,b   Vats, Ishwar Dutt ^a   Chopra, Madhu ^c   Biswas, Parbati ^b   Pasha, Santosh ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF DELHI   (India)

^c UNIVERSITY OF DELHI   (India)

Author keywords

ACE Inhibitors; Discovery studio; Docking; LUDI; Tripeptidomimics

Indexed keywords

AMINO ACID; CARBOXYLIC ACID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HETEROCYCLIC COMPOUND; ORNITHYL PROLINE; PROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CARBON; CATALYTIC DOMAIN; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; HUMANS; INDOLES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PEPTIDES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 67649971812     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.079     Document Type: Article

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