메뉴 건너뛰기




Volumn 9, Issue 3, 2009, Pages 135-148

Prediction of polyadenylation signals in human DNA sequences using nucleotide frequencies

Author keywords

Matthews correlation coefficient (MCC); mRNA; Nucleotide frequency; Polyadenylation signals; ROC plot; Support Vector Machine (SVM)

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; DINUCLEOTIDE; DNA; MESSENGER RNA; NUCLEOTIDE; POLYADENYLIC ACID; TRINUCLEOTIDE;

EID: 67649876421     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: 10.3233/ISB-2009-0395     Document Type: Article
Times cited : (46)

References (37)
  • 1
    • 34547851778 scopus 로고    scopus 로고
    • A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor
    • Addepalli, B. and Hunt, A. G. (2007). A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor. Nucleic Acids Res. 35, 4453-4463.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4453-4463
    • Addepalli, B.1    Hunt, A.G.2
  • 2
    • 38949111543 scopus 로고    scopus 로고
    • 3′ end mRNA processing: Molecular mechanisms and implications for health and disease
    • Danckwardt, S., Hentze, M. W. and Kulozik, A. E. (2008). 3′ end mRNA processing: Molecular mechanisms and implications for health and disease. EMBO J. 27, 482-498.
    • (2008) EMBO J , vol.27 , pp. 482-498
    • Danckwardt, S.1    Hentze, M.W.2    Kulozik, A.E.3
  • 3
    • 19344365530 scopus 로고    scopus 로고
    • Connections between mRNA 3′ end processing and transcription termination
    • Buratowski, S. (2005). Connections between mRNA 3′ end processing and transcription termination. Curr. Opin. Cell Biol. 17, 257-261.
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 257-261
    • Buratowski, S.1
  • 4
    • 0037154964 scopus 로고    scopus 로고
    • A conserved mRNA export machinery coupled to pre-mRNA splicing
    • Reed, R. and Hurt, E. (2002). A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell 108, 523-531.
    • (2002) Cell , vol.108 , pp. 523-531
    • Reed, R.1    Hurt, E.2
  • 5
    • 0037154967 scopus 로고    scopus 로고
    • Integrating mRNA processing with transcription
    • Proudfoot, N. J., Furger, A. and Dye, M. J. (2002). Integrating mRNA processing with transcription. Cell 108, 501-512.
    • (2002) Cell , vol.108 , pp. 501-512
    • Proudfoot, N.J.1    Furger, A.2    Dye, M.J.3
  • 6
    • 0022021842 scopus 로고
    • Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene
    • Orkin, S. H., Cheng, T. C., Antonarakis, S. E. and Kazazian, H. H., Jr. (1985). Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene. EMBO J. 4, 453-456.
    • (1985) EMBO J , vol.4 , pp. 453-456
    • Orkin, S.H.1    Cheng, T.C.2    Antonarakis, S.E.3    Kazazian Jr., H.H.4
  • 7
    • 0035320036 scopus 로고    scopus 로고
    • mRNA localization: Message on the move
    • Jansen, R. P. (2001). mRNA localization: Message on the move. Nat. Rev. Mol. Cell Biol. 2, 247-256.
    • (2001) Nat. Rev. Mol. Cell Biol , vol.2 , pp. 247-256
    • Jansen, R.P.1
  • 8
    • 0031586003 scopus 로고    scopus 로고
    • Prediction of complete gene structures in human genomic DNA
    • Burge, C. and Karlin, S. (1997). Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268, 78-94.
    • (1997) J. Mol. Biol , vol.268 , pp. 78-94
    • Burge, C.1    Karlin, S.2
  • 9
    • 0036166511 scopus 로고    scopus 로고
    • Locating probable genes using Fourier transform approach
    • Issac, B., Singh, H., Kaur, H. and Raghava, G. P. (2002). Locating probable genes using Fourier transform approach. Bioinformatics 18 196-197.
    • (2002) Bioinformatics , vol.18 , pp. 196-197
    • Issac, B.1    Singh, H.2    Kaur, H.3    Raghava, G.P.4
  • 10
    • 4644295707 scopus 로고    scopus 로고
    • EGPred: Prediction of eukaryotic genes using ab initio methods after combining with sequence similarity approaches
    • Issac, B. and Raghava, G. P. (2004). EGPred: Prediction of eukaryotic genes using ab initio methods after combining with sequence similarity approaches. Genome Res. 14, 1756-1766.
    • (2004) Genome Res , vol.14 , pp. 1756-1766
    • Issac, B.1    Raghava, G.P.2
  • 11
    • 3142727129 scopus 로고    scopus 로고
    • Spectral Repeat Finder (SRF): Identification of repetitive sequences using Fourier transformation
    • Sharma, D., Issac, B., Raghava, G. P. and Ramaswamy, R. (2004). Spectral Repeat Finder (SRF): Identification of repetitive sequences using Fourier transformation. Bioinformatics 20, 1405-1412.
    • (2004) Bioinformatics , vol.20 , pp. 1405-1412
    • Sharma, D.1    Issac, B.2    Raghava, G.P.3    Ramaswamy, R.4
  • 12
    • 0033598805 scopus 로고    scopus 로고
    • In silico detection of control signals: MRNA 3′-end-processing sequences in diverse species
    • Graber, J. H., Cantor, C. R., Mohr, S. C. and Smith, T. F. (1999). In silico detection of control signals: MRNA 3′-end-processing sequences in diverse species. Proc. Natl. Acad. Sci. USA 96, 14055-14060.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14055-14060
    • Graber, J.H.1    Cantor, C.R.2    Mohr, S.C.3    Smith, T.F.4
  • 13
    • 3242672609 scopus 로고    scopus 로고
    • A probabilistic model of 3′ end formation in Caenorhabditis elegans
    • Hajarnavis, A., Korf, I. and Durbin, R. (2004). A probabilistic model of 3′ end formation in Caenorhabditis elegans. Nucleic Acids Res. 32, 3392-3399.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3392-3399
    • Hajarnavis, A.1    Korf, I.2    Durbin, R.3
  • 14
    • 13744254695 scopus 로고    scopus 로고
    • A large-scale analysis of mRNA polyadenylation of human and mouse genes
    • Tian, B., Hu, J., Zhang, H. and Lutz, C. S. (2005). A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res. 33, 201-212.
    • (2005) Nucleic Acids Res , vol.33 , pp. 201-212
    • Tian, B.1    Hu, J.2    Zhang, H.3    Lutz, C.S.4
  • 15
    • 25844497003 scopus 로고    scopus 로고
    • Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation
    • Hu, J., Lutz, C. S., Wilusz, J. and Tian, B. (2005). Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation. RNA 11, 1485-1493.
    • (2005) RNA , vol.11 , pp. 1485-1493
    • Hu, J.1    Lutz, C.S.2    Wilusz, J.3    Tian, B.4
  • 16
    • 0033858202 scopus 로고    scopus 로고
    • Patterns of variant polyadenylation signal usage in human genes
    • Beaudoing, E., Freier, S., Wyatt, J. R., Claverie, J. M. and Gautheret, D. (2000). Patterns of variant polyadenylation signal usage in human genes. Genome Res. 10, 1001-1010.
    • (2000) Genome Res , vol.10 , pp. 1001-1010
    • Beaudoing, E.1    Freier, S.2    Wyatt, J.R.3    Claverie, J.M.4    Gautheret, D.5
  • 17
    • 0030932502 scopus 로고    scopus 로고
    • Recognition of 3′-processing sites of human mRNA precursors
    • Salamov, A. A. and Solovyev, V. V. (1997). Recognition of 3′-processing sites of human mRNA precursors. Comput. Appl. Biosci. 13, 23-28.
    • (1997) Comput. Appl. Biosci , vol.13 , pp. 23-28
    • Salamov, A.A.1    Solovyev, V.V.2
  • 18
    • 0033614456 scopus 로고    scopus 로고
    • Detection of polyadenylation signals in human DNA sequences
    • Tabaska, J. E. and Zhang, M. Q. (1999). Detection of polyadenylation signals in human DNA sequences. Gene 231, 77-86.
    • (1999) Gene , vol.231 , pp. 77-86
    • Tabaska, J.E.1    Zhang, M.Q.2
  • 19
    • 0242292336 scopus 로고    scopus 로고
    • Sequence determinants in human polyadenylation site selection
    • Legendre, M. and Gautheret, D. (2003). Sequence determinants in human polyadenylation site selection. BMC Genomics 4, 7.
    • (2003) BMC Genomics , vol.4 , pp. 7
    • Legendre, M.1    Gautheret, D.2
  • 20
    • 10044280127 scopus 로고    scopus 로고
    • An in-silico method for prediction of polyadenylation signals in human sequences
    • Liu, H., Han, H., Li, J. and Wong, L. (2003). An in-silico method for prediction of polyadenylation signals in human sequences. Genome Inform. 14, 84-93.
    • (2003) Genome Inform , vol.14 , pp. 84-93
    • Liu, H.1    Han, H.2    Li, J.3    Wong, L.4
  • 21
    • 33749997848 scopus 로고    scopus 로고
    • Prediction of mRNA polyadenylation sites by support vector machine
    • Cheng, Y., Miura, R. M. and Tian, B. (2006). Prediction of mRNA polyadenylation sites by support vector machine. Bioinformatics 22 2320-2325.
    • (2006) Bioinformatics , vol.22 , pp. 2320-2325
    • Cheng, Y.1    Miura, R.M.2    Tian, B.3
  • 22
    • 0002714543 scopus 로고    scopus 로고
    • Making large-scale support vector machine learning practical
    • MIT Press, pp
    • Joachims, T. (1999). Making large-scale support vector machine learning practical. In: AdvanceS in kernel methods: support vector learning. MIT Press, pp. 169-184.
    • (1999) AdvanceS in kernel methods: Support vector learning , pp. 169-184
    • Joachims, T.1
  • 24
    • 0037407019 scopus 로고    scopus 로고
    • A neural-network based method for prediction of gamma-turns in proteins from multiple sequence alignment
    • Kaur, H. and Raghava, G. P. (2003). A neural-network based method for prediction of gamma-turns in proteins from multiple sequence alignment. Protein Sci. 12, 923-929.
    • (2003) Protein Sci , vol.12 , pp. 923-929
    • Kaur, H.1    Raghava, G.P.2
  • 25
    • 17644389617 scopus 로고    scopus 로고
    • Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search
    • Garg, A., Bhasin, M. and Raghava, G. P. (2005). Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search. J. Biol. Chem. 280, 14427-14432.
    • (2005) J. Biol. Chem , vol.280 , pp. 14427-14432
    • Garg, A.1    Bhasin, M.2    Raghava, G.P.3
  • 26
    • 33747871140 scopus 로고    scopus 로고
    • AlgPred: Prediction of allergenic proteins and mapping of IgE epitopes
    • Saha, S. and Raghava, G. P. (2006). AlgPred: Prediction of allergenic proteins and mapping of IgE epitopes. Nucleic Acids Res. 34, W202-209.
    • (2006) Nucleic Acids Res , vol.34
    • Saha, S.1    Raghava, G.P.2
  • 27
    • 23144436397 scopus 로고    scopus 로고
    • BhairPred: Prediction of beta-hairpins in a protein from multiple alignment information using ANN and SVM techniques
    • Kumar, M., Bhasin, M., Natt, N. K. and Raghava, G. P. (2005). BhairPred: prediction of beta-hairpins in a protein from multiple alignment information using ANN and SVM techniques. Nucleic Acids Res. 33, W154-159.
    • (2005) Nucleic Acids Res , vol.33
    • Kumar, M.1    Bhasin, M.2    Natt, N.K.3    Raghava, G.P.4
  • 28
    • 33646852452 scopus 로고    scopus 로고
    • Prediction of mitochondrial proteins using support vector machine and hidden Markov model
    • Kumar, M., Verma, R. and Raghava, G. P. (2006). Prediction of mitochondrial proteins using support vector machine and hidden Markov model. J. Biol. Chem. 281, 5357-5363.
    • (2006) J. Biol. Chem , vol.281 , pp. 5357-5363
    • Kumar, M.1    Verma, R.2    Raghava, G.P.3
  • 29
    • 33751287730 scopus 로고    scopus 로고
    • Machine learning techniques in disease forecasting: A case study on rice blast prediction
    • Kaundal, R., Kapoor, A. S. and Raghava, G. P. (2006). Machine learning techniques in disease forecasting: A case study on rice blast prediction. BMC Bioinformatics 7, 485.
    • (2006) BMC Bioinformatics , vol.7 , pp. 485
    • Kaundal, R.1    Kapoor, A.S.2    Raghava, G.P.3
  • 30
    • 37249045159 scopus 로고    scopus 로고
    • Prediction of neurotoxins based on their function and source
    • Saha, S. and Raghava, G. P. (2007). Prediction of neurotoxins based on their function and source. In Silico Biol. 7, 369-387.
    • (2007) In Silico Biol , vol.7 , pp. 369-387
    • Saha, S.1    Raghava, G.P.2
  • 31
    • 44349130371 scopus 로고    scopus 로고
    • Genome level analysis of rice mRNA 3′-end processing signals and alternative polyadenylation
    • Shen, Y., Ji, G., Haas, B. J., Wu, X., Zheng, J., Reese, G. J. and Li, Q. Q. (2008). Genome level analysis of rice mRNA 3′-end processing signals and alternative polyadenylation. Nucleic Acids Res. 36, 3150-3161.
    • (2008) Nucleic Acids Res , vol.36 , pp. 3150-3161
    • Shen, Y.1    Ji, G.2    Haas, B.J.3    Wu, X.4    Zheng, J.5    Reese, G.J.6    Li, Q.Q.7
  • 32
    • 0023890867 scopus 로고
    • Measuring the accuracy of diagnostic systems
    • Swets, J. A. (1988). Measuring the accuracy of diagnostic systems. Science 240, 1285-1293.
    • (1988) Science , vol.240 , pp. 1285-1293
    • Swets, J.A.1
  • 33
    • 0037335613 scopus 로고    scopus 로고
    • Downstream elements of mammalian pre-mRNA polyadenylation signals: Primary, secondary and higher-order structures
    • Zarudnaya, M. I., Kolomiets, I. M., Potyahaylo, A. L. and Hovorun, D. M. (2003). Downstream elements of mammalian pre-mRNA polyadenylation signals: Primary, secondary and higher-order structures. Nucleic Acids Res. 31, 1375-1386.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1375-1386
    • Zarudnaya, M.I.1    Kolomiets, I.M.2    Potyahaylo, A.L.3    Hovorun, D.M.4
  • 34
    • 0030920331 scopus 로고    scopus 로고
    • RNA recognition by the human polyadenylation factor CstF
    • Takagaki, Y. and Manley, J. L. (1997). RNA recognition by the human polyadenylation factor CstF. Mol. Cell Biol. 17, 3907-3914.
    • (1997) Mol. Cell Biol , vol.17 , pp. 3907-3914
    • Takagaki, Y.1    Manley, J.L.2
  • 35
    • 0033039863 scopus 로고    scopus 로고
    • Specific transcriptional pausing activates polyadenylation in a coupled in vitro system
    • Yonaha, M. and Proudfoot, N. J. (1999). Specific transcriptional pausing activates polyadenylation in a coupled in vitro system. Mol. Cell. 3 593-600.
    • (1999) Mol. Cell , vol.3 , pp. 593-600
    • Yonaha, M.1    Proudfoot, N.J.2
  • 36
    • 3242877807 scopus 로고    scopus 로고
    • ESLpred: SVM-based method for subcellular localization of eukaryotic proteins using dipeptide composition and PSI-BLAST
    • Bhasin, M. and Raghava, G. P. (2004). ESLpred: SVM-based method for subcellular localization of eukaryotic proteins using dipeptide composition and PSI-BLAST. Nucleic Acids Res. 32, W414-419.
    • (2004) Nucleic Acids Res , vol.32
    • Bhasin, M.1    Raghava, G.P.2
  • 37
    • 19544388127 scopus 로고    scopus 로고
    • PSLpred: Prediction of subcellular localization of bacterial proteins
    • Bhasin, M., Garg, A. and Raghava, G. P. (2005). PSLpred: Prediction of subcellular localization of bacterial proteins. Bioinformatics 21, 2522-2524.
    • (2005) Bioinformatics , vol.21 , pp. 2522-2524
    • Bhasin, M.1    Garg, A.2    Raghava, G.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.