Role of IL-23 in mobilization of immunoregulatory nitric oxide- or superoxide-producing Gr-1+ cells from bone marrow

Free Radical Biology and Medicine

Volumn 47, Issue 4, 2009, Pages 357-363

  Dietlin, Therese A ^a   Cua, Daniel J ^b   Burke, Kathleen A ^a   Lund, Brett T ^a   van der Veen, Roel C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Schering Plough Biopharma ^*  (United States)

Author keywords

Bacterial products; Bone marrow; Free radicals; Immunosuppression; Myeloid cells; Nitric oxide; Superoxide

Indexed keywords

CELL PROTEIN; INTERLEUKIN 23; NITRIC OXIDE; OXYGEN; PROTEIN GR 1; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; BONE MARROW CELL; CELL FUNCTION; CELL MOTILITY; CONTROLLED STUDY; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, LY; AUTOIMMUNITY; BONE MARROW CELLS; CELL PROLIFERATION; HEMATOPOIETIC STEM CELL MOBILIZATION; HOT TEMPERATURE; IMMUNE TOLERANCE; IMMUNIZATION; INTERLEUKIN-23; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; OVALBUMIN; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CHEMOKINE; SPLEEN; SUPEROXIDES; T-LYMPHOCYTES;

BACTERIA (MICROORGANISMS); MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 67649867919     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.04.029     Document Type: Article

References (39)

1. Bogdan C. Nitric oxide and the immune response. Nat. Immunol. 2 (2001) 907-916
2. Kahn D.A., Archer D.C., Gold D.P., and Kelly C.J. Adjuvant immunotherapy is dependent on inducible nitric oxide synthase. J. Exp. Med. 193 (2001) 1261-1267
3. Weishaupt A., Jander S., Bruck W., Kuhlmann T., Stienekemeier M., Hartung T., Toyka K.V., Stoll G., and Gold S. Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: rapid induction of Th1-type cytokines and inducible nitric oxide synthase. J. Immunol. 165 (2000) 7157-7163
4. Pelaez B., Campillo J.A., Lopez-Asenjo J.A., and Subiza J.L. Cyclophosphamide induces the development of early myeloid cells suppressing tumor cell growth by a nitric oxide-dependent mechanism. J. Immunol. 166 (2001) 6608-6615
5. Shi F.-D., Flodstrom M., Kim S.H., Pakala S., Cleary M., Ljunggren H.-G., and Sarvetnick N. Control of the autoimmune response by type 2 nitric oxide synthase. J. Immunol. 167 (2001) 3000-3006
6. McCartney-Francis N.L., Song X., Mizel D.E., and Wahl S.M. Selective inhibition of inducible nitric oxide synthase exacerbates erosive joint disease. J. Immunol. 166 (2001) 2734-2740
7. Eriksson U., Kurrer M.O., Bingisser R., Eugster H.P., Saremaslani P., Follath F., Marsch S., and Widmer U. Lethal autoimmune myocarditis in interferon-gamma receptor-deficient mice: enhanced disease severity by impaired inducible nitric oxide synthase induction. Circulation 103 (2001) 18-21
8. Sahrbacher U.C., Lechner F., Eugster H.P., Frei K., Lassmann H., and Fontana A. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis. Eur. J. Immunol. 28 (1998) 1332-1338
9. Fenyk-Melody J.E., Garrison A.E., Brunnert S.R., Weidner J.R., Shen F., Shelton B.A., and Mudgett J.S. Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene. J. Immunol. 160 (1998) 2940-2946
10. Marchetti B., Morale M.C., Brouwer J., Tirolo C., Testa N., Caniglia S., Barden N., Amor S., Smith P.A., and Dijkstra C.D. Exposure to a dysfunctional glycocorticoid receptor from early embryonic life programs the resistance to experimental autoimmune encephalomyelitis via nitric oxide-induced immuno-suppression. J. Immunol. 168 (2002) 5848-5859
11. Millar A.E., Sternberg J., McSharry C., Wei X.-Q., Liew F.Y., and Turner M.R. T cell responses during Trypanosoma brucei infections in mice deficient in inducible nitric oxide synthase. Infect. Immun. 67 (1999) 3334-3338
12. Juedes A.E., and Ruddle N.H. Resident and infiltrating central nervous system APCs regulate the emergence and resolution of EAE. J. Immunol. 166 (2001) 5168-5175
13. Tarrant T.K., Silver P.B., Wahlsten J.L., Rizzo L.V., Chan C.-C., Wiggert B., and Caspi R.R. Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon γ, nitric oxide and apoptosis. J. Exp. Med. 189 (1999) 219-230
14. van der Veen R.C., Dietlin T.A., Pen L., Gray J.D., and Hofman F.M. Antigen presentation to Th1 but not Th2 cells by macrophages results in nitric oxide production and inhibition of T cell proliferation: interferon-gamma is essential but insufficient. Cell. Immunol. 206 (2000) 125-135
15. Henson S.E., Nichols T.C., Holers V.M., and Karp D.R. The ectoenzyme γ-glutamyl transpeptidase regulates antiproliferative effects of S-nitrosoglutathione on human T and B lymphocytes. J. Immunol. 163 (1999) 1845-1852
16. Clark S.R., Coffey M.J., Maclean R.M., Collins P.W., Lewis M.J., Cross A.R., and O'Donnell V.B. Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils. J. Immunol. 169 (2002) 5889-5896
17. van der Veen R.C., Dietlin T.A., Hofman F.M., Pen L., Segal B.H., and Holland S.M. Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in NADPH oxidase knockout mice. J. Immunol. 164 (2000) 5177-5183
18. Staykova M.A., Fordham S.A., Bartell G.J., Cowden W.B., and Willenborg D.O. Nitric oxide contributes to the resistance of young SJL/J mice to EAE. J. Neuroimmunol. 176 (2006) 1-8
19. Aslan M., Ryan T.M., Adler B., Townes T.M., Parks D.A., Thompson J.A., Gladwin M.T., Patel R.P., Tarpey M.M., Batinic-Haberle I., White C.R., and Freeman B.A. Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 15215-15220
20. Kausalya S., and Nath J. Interactive role of NO and superoxide anion in neutrophil-mediated endothelial cell injury. J. Leukocyte Biol. 64 (1998) 185-191
21. van der Veen R.C., Dietlin T.A., Karapetian A., Holland S.M., and Hofman F.M. Extra-cellular superoxide promotes T cell expansion through inactivation of nitric oxide. J. Neuroimmunol. 153 (2004) 183-189
22. + T cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism. J. Immunol. 167 (2001) 4293-4302
23. Mazzoni A., Bronte V., Visintin A., Spitzer J.H., Apolloni E., Serafini P., Zanovello P., and Segal D.M. Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J. Immunol. 168 (2002) 689-695
24. Kusmartsev S., and Gabrilovich D.I. Immature myeloid cells and cancer-associated immune suppression. Cancer Immunol. Immunother. 51 (2002) 293-298
25. Cauley L.S., Miller E.E., Yen M., and Swain S.L. Superrantigen-induced CD-4 T cell tolerance mediated by myeloid cells and IFN-γ. J. Immunol. 165 (2000) 6056-6066
26. + splenocytes. Cell. Immunol. 235 (2005) 39-45
27. +) CD11b immature myeloid suppressor cells. Intern. Immunol. 14 (2002) 1125-1134
28. Billiau A.D., Fevery S., Rutgeerts O., Landuyt W., and Waer M. Transient expansion of Mac1 Ly-6G Ly-6C early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras. Blood 102 (2003) 740-748
29. + subsets from distinct myeloid lineages have opposite effects on T cell expansion. J. Leukocyte Biol. 81 (2007) 1205-1212
30. Cua D.J., Sherlock J., Chen Y., Murphy C.A., Joyce B., Seymour B., Lucian L., Kwan S., Churakova T., Zurawski S., Wiekowski M., Lira S.A., Gorman D., Kastelein R.A., and Sedgwick J.D. IL-23 rather than IL-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421 (2003) 744-748
31. Stark M.A., Huo Y., Burcin T.L., Morris M.A., Olson T.S., and Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22 (2005) 286-294
32. Serbina N.V., and Pamer E.G. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 7 (2006) 311-317
33. Iida S., Kohro T., Kodama T., Nagata S., and Fuganaga R. Identification of CCR2, flotillin, and gp49B genes as new targets during neutrophilic differentiation. J. Leukocyte Biol. 78 (2005) 481-490
34. Kim K.H., De La Cruz Sierra M., Williams C.K., Gulino A.V., and Tosato G. G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells. Blood 108 (2006) 812-820
35. Thakker P., Leach M.W., Kuang W., Benoit S.E., Leonard J.P., and Marusic S. IL-23 is critical in the induction not in the effector phase of EAE. J. Immunol. 178 (2007) 2589-2598
36. Openshaw H., Stuve O., Antel J.P., Nash R., Lund B.T., Weiner L.P., Kashyap A., McSweeney P., and Forman S. Multiple sclerosis flares associated with recombinant G-CSF. Neurology 54 (2000) 2147-2150
37. + T cell responses by immature myeloid cells in cancer is mediated by reactive oxygen species. J. Immunol. 172 (2004) 989-999
38. Choi J.Y., Oughton J.A., and Kerkvliet N.I. Functional alterations in CD11b(+)Gr-1(+) cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Int. Immunopharmacol. 3 (2003) 553-570
39. Sharma R., Muttil P., Yadav A.B., Rath S.K., Bajpai V.K., Mani U., and Misra A. Uptake of inhalable microparticles affects defence responses of macrophages infected with Mycobacterium tuberculosis H37Ra. J. Antimicrob. Chemother. 59 (2007) 499-506