The block of DNA polymerase δ strand displacement activity by an abasic site can be rescued by the concerted action ofDNA polymerase β and flap endonuclease 1

Journal of Biological Chemistry

Volumn 284, Issue 21, 2009, Pages 14267-14275

  Maga, Giovanni ^a   van Loon, Barbara ^b   Crespan, Emmanuele ^a   Villani, Giuseppe ^c   Hübscher, Ulrich ^b  

^a CNR   (Italy)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AP-SITES; CELL METABOLISM; DELETERIOUS EFFECTS; DNA LESIONS; DNA POLYMERASE; FLAP ENDONUCLEASE-1; FUNCTIONAL INTERACTION; INHIBITORY EFFECT; LAGGING STRAND; OKAZAKI FRAGMENTS; REPAIR PATHWAYS; REPLICATION FORK;

DNA; FUNCTIONAL POLYMERS; METABOLISM; NUCLEIC ACIDS; POLYMERS;

GENES;

CYCLINE; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE DELTA; DNA POLYMERASE; DNA POLYMERASE LAMBDA; DOUBLE STRANDED DNA; FLAP ENDONUCLEASE; FLAP ENDONUCLEASE 1; OKAZAKI FRAGMENT; OLIGONUCLEOTIDE; REPLICATION FACTOR A; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; DNA; DNA DIRECTED DNA POLYMERASE GAMMA; POLD1 PROTEIN, HUMAN;

ABASIC SITE; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DNA DAMAGE; DNA FLANKING REGION; DNA REPLICATION; DNA STRAND; DNA SYNTHESIS; DNA TEMPLATE; GENE SWITCHING; HUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; BIOLOGICAL MODEL; METABOLISM; PROTEIN BINDING;

DNA; DNA DAMAGE; DNA POLYMERASE BETA; DNA POLYMERASE III; DNA REPLICATION; FLAP ENDONUCLEASES; HUMANS; MODELS, BIOLOGICAL; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN BINDING; TEMPLATES, GENETIC;

EID: 67649816708     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M900759200     Document Type: Article

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