GlcNAc6ST-1-mediated decoration of MAdCAM-1 protein with L-selectin ligand carbohydrates directs disease activity of ulcerative colitis

Inflammatory Bowel Diseases

Volumn 15, Issue 5, 2009, Pages 697-706

  Kobayashi, Motohiro ^a   Hoshino, Hitomi ^a   Masumoto, Junya ^a   Fukushima, Mana ^b   Suzawa, Kenichi ^a,b   Kageyama, Shunsuke ^a   Suzuki, Manabu ^a   Ohtani, Haruo ^c   Fukuda, Minoru ^d   Nakayama, Jun ^a  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY HOSPITAL   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION MITO MEDICAL CENTER   (Japan)

^d BURNHAM INSTITUTE   (United States)

Author keywords

L selectin ligand carbohydrate; Mucosal addressin cell adhesion molecule 1 (MAdCAM 1); Peripheral lymph node addressin (PNAd); Posttranslational modification; Ulcerative colitis

Indexed keywords

CARBOHYDRATE; CD34 ANTIGEN; L SELECTIN; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; N ACETYLGLUCOSAMINE 6 O SULFOTRANSFERASE; PENICILLIN BINDING PROTEIN 2A; PROTEIN MECA 79; SCAFFOLD PROTEIN; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; COLON BIOPSY; CONTROLLED STUDY; DISEASE ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ULCERATIVE COLITIS; WESTERN BLOTTING;

ANIMALS; ANTIGENS, SURFACE; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CHO CELLS; COLITIS, ULCERATIVE; CRICETINAE; CRICETULUS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULINS; L-SELECTIN; LIGANDS; MEMBRANE PROTEINS; MUCOPROTEINS; OLIGOSACCHARIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFOTRANSFERASES;

EID: 67649736425     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20827     Document Type: Article

References (37)

1. Friedman S, Blumberg RS. Inflammatory bowel disease. In: Braunwald E, Fauci AS, Kasper DL, et al., eds. Harrison's Principles of Internal Medicine, 15th ed. New York: McGraw-Hill; 2001:1679-1692.
2. Liu C, Crawford JM. The gastrointestinal tract. In: Kumar V, Abbas AK, Fausto N, eds. Robbins and Cotran Pathologic Basis of Disease, 7th ed. Philadelphia: Elsevier Saunders; 2005:846-851.
3. Salmi M, Jalkanen S. Endothelial ligands and homing of mucosal leukocytes in extraintestinal manifestations of IBD. Inflamm Bowel Dis. 1998;4:149-156.
4. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science. 1996;272:60-66.
5. von Andrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol. 2003;3:867-878.
6. Michie SA, Streeter PR, Bolt PA, et al. The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing. Am J Pathol. 1993;143:1688-1698.
7. Berlin C, Berg EL, Briskin MJ, et al. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell. 1993;74:185-195.
8. Streeter PR, Rouse BT, Butcher EC. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J Cell Biol. 1988;107:1853-1862.
9. Rosen SD. Ligand for L-selectin: homing, inflammation, and beyond. Annu Rev Immunol. 2004;22:129-156.
10. Yeh JC, Hiraoka N, Petryniak B, et al. Novel sulfated lymphocyte homing receptors and their control by a core 1 extension β1,3-N-acetylglucosaminyltransferase. Cell. 2001; 105:957-969.
11. Aloisi F, Pujol-Borrell R. Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol. 2006;6:205-217.
12. Renkonen J, Tynninen O, Hayry P, et al. Glycosylation might provide endothelial zip codes for organ-specific leukocyte traffic into inflammatory sites. Am J Pathol. 2002;161:543-550.
13. Kobayashi M, Mitoma J, Nakamura N, et al. Induction of peripheral lymph node addressin in human gastric mucosa infected by Helicobacter pylori. Proc Natl Acad Sci U S A. 2004;101:17807-17812.
14. Suzawa K, Kobayashi M, Sakai Y, et al. Preferential induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis. Am J Gastroenterol. 2007;102: 1499-1509.
15. Briskin M, Winsor-Hines D, Shyjan A, et al. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol. 1997;151:97-110.
16. Bargatze RF, Jutila MA, Butcher EC. Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined. Immunity. 1995;3: 99-108.
17. Berlin C, Bargatze RF, Campbell JJ, et al. α4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell. 1995;80: 413-422.
18. Berg EL, McEvoy LM, Berlin C, et al. L-selectin-mediated lymphocyte rolling on MAdCAM-1. Nature. 1993;366:695-698.
19. Souza HS, Elia CC, Spencer J, et al. Expression of lymphocyte-endothelial receptor-ligand pairs, α4β7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease. Gut. 1999;45:856-863.
20. Arihiro S, Ohtani H, Suzuki M, et al. Differential expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in ulcerative colitis and Crohn's disease. Pathol Int. 2002;52:367-374.
21. Imai Y, Lasky LA, Rosen SD. Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin. Nature. 1993;361:555-557.
22. Hiraoka N, Petryniak B, Nakayama J, et al. A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewisx, an L-selectin ligand displayed by CD34. Immunity. 1999;11:79-89.
23. Fukuda M, Hiraoka N, Akama TO, et al. Carbohydrate-modifying sulfotransferases: structure, function, and pathophysiology. J Biol Chem. 2001;276:47747-47750.
24. Uchimura K, Muramatsu H, Kaname T, et al. Human N-acetylglucosamine- 6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells. J Biochem. 1998; 124:670-678.
25. Uchimura K, Kadomatsu K, El-Fasakhany FM, et al. N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. J Biol Chem. 2004;279:35001-35008.
26. Shyjan AM, Bertagnolli M, Kenney CJ, et al. Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the α4β7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. J Immunol. 1996;156:2851-2857.
27. Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987;317:1625-1629.
28. Bibiloni R, Fedorak RN, Tannock GW, et al. VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis. Am J Gastroenterol. 2005;100:1539-1546.
29. Nakai K, Horton P. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem Sci. 1999;24:34-36.
30. Aruffo A, Stamenkovic I, Melnick M, et al. CD44 is the principal cell surface receptor for hyaluronate. Cell. 1990;61:1303-1313.
31. Deutscher SL, Nuwayhid N, Stanley P, et al. Translocation across Golgi vesicle membranes: a CHO glycosylation mutant deficient in CMP-sialic acid transport. Cell. 1984;39:295-299.
32. Maly P, Thall A, Petryniak B, et al. The α(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 1996;86:643-653.
33. Duijvestijn AM, Horst E, Pals ST, et al. High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452. Am J Pathol. 1988;130:147-155.
34. Farstad IN, Halstensen TS, Kvale D, et al. Topographic distribution of homing receptors on B and T cells in human gut-associated lymphoid tissue: relation of L-selectin and integrin α4β7 to naive and memory phenotypes. Am J Pathol. 1997;150:187-199.
35. Kawashima H, Petryniak B, Hiraoka N, et al. N-acetylglucosamine-6- O-sulfotransferase 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules. Nat Immunol. 2005;6:1096-1104.
36. de Graffenried CL, Bertozzi CR. The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity. J Biol Chem. 2004;279:40035-40043.
37. de Graffenried CL, Bertozzi CR. Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis. J Biol Chem. 2003;278:40282-40295.