Preferential induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis

American Journal of Gastroenterology

Volumn 102, Issue 7, 2007, Pages 1499-1509

  Suzawa, Kenichi ^a   Kobayashi, Motohiro ^a   Sakai, Yasuhiro ^a   Hoshino, Hitomi ^a   Watanabe, Matsuko ^a   Harada, Oi ^a   Ohtani, Haruo ^b   Fukuda, Minoru ^c   Nakayama, Jun ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION MITO MEDICAL CENTER   (Japan)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; CD3 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CD79 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE RECEPTOR CXCR3; IMMUNOGLOBULIN M; L SELECTIN; PERIPHERAL LYMPH NODE ADDRESSIN; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; COLON BIOPSY; CONTROLLED STUDY; CORRELATION ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LYMPHOCYTE SUBPOPULATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ULCERATIVE COLITIS; UPREGULATION; VASCULAR ENDOTHELIUM; VENULE;

ANTIGENS, CD34; ANTIGENS, SURFACE; BIOPSY; COLITIS, ULCERATIVE; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; HUMANS; INTESTINAL MUCOSA; L-SELECTIN; LIGNANS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; RECEPTORS, LYMPHOCYTE HOMING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SULFOTRANSFERASES; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC; UP-REGULATION; VENULES;

EID: 34250890337     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2007.01189.x     Document Type: Article

References (36)

1. Friedman S, Blumberg RS. Inflammatory bowel disease. In : Braunwald E, Fauci AS, Kasper DL, et al., eds. Harrison's principles of internal medicine, 15th Ed. New York : McGraw-Hill, 2001 : 1679 92.
2. Crawford JM. The gastrointestinal tract. In : Cotran RS, Kumar V, Collins T, eds. Pathologic basis of disease, 6th Ed. Philadelphia : WB Saunders, 1999 : 815 20.
3. Jinno Y, Ohtani H, Nakamura S, et al. Infiltration of CD19+ plasma cells with frequent labeling of Ki-67 in corticosteroid-resistant active ulcerative colitis. Virchows Arch 2006 448 : 412 21.
4. Salmi M, Jalkanen S. Endothelial ligands and homing of mucosal leukocytes in extraintestinal manifestations of IBD. Inflamm Bowel Dis 1998 4 : 149 56.
5. Michie SA, Streeter PR, Bolt PA, et al. The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing. Am J Pathol 1993 143 : 1688 98.
6. Berlin C, Berg EL, Briskin MJ, et al. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993 74 : 185 95.
7. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994 76 : 301 14.
8. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996 272 : 60 6.
9. Briskin M, Winsor-Hines D, Shyjan A, et al. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol 1997 151 : 97 110.
10. Arihiro S, Ohtani H, Suzuki M, et al. Differential expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in ulcerative colitis and Crohn's disease. Pathol Int 2002 52 : 367 74.
11. Rosen SD. Ligand for L-selectin: Homing, inflammation, and beyond. Annu Rev Immunol 2004 22 : 129 56.
12. Aloisi F, Pujol-Borrell R. Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol 2006 6 : 205 17.
13. Renkonen J, Tynninen O, Hayry P, et al. Glycosylation might provide endothelial zip codes for organ-specific leukocyte traffic into inflammatory sites. Am J Pathol 2002 161 : 543 50.
14. van Dinther-Janssen AC, Pals ST, Scheper R, et al. Dendritic cells and high endothelial venules in the rheumatoid synovial membrane. J Rheumatol 1990 17 : 11 7.
15. Kabel PJ, Voorbij HA, de Haan-Meulman M, et al. High endothelial venules present in lymphoid cell accumulations in thyroids affected by autoimmune disease: A study in men and BB rats of functional activity and development. J Clin Endocrinol Metab 1989 68 : 744 51.
16. Kobayashi M, Mitoma J, Nakamura N, et al. Induction of peripheral lymph node addressin in human gastric mucosa infected by Helicobacter pylori. Proc Natl Acad Sci U S A 2004 101 : 17807 12.
17. Salmi M, Granfors K, MacDermott R, et al. Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel diseases. Gastroenterology 1994 106 : 596 605.
18. Streeter PR, Rouse BT, Butcher EC. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J Cell Biol 1988 107 : 1853 62.
19. Yeh JC, Hiraoka N, Petryniak B, et al. Novel sulfated lymphocyte homing receptors and their control by a Core1 extension β1,3-N- acetylglucosaminyltransferase. Cell 2001 105 : 957 69.
20. Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 1987 317 : 1625 9.
21. Bibiloni R, Fedorak RN, Tannock GW, et al. VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis. Am J Gastroenterol 2005 100 : 1539 46.
22. Geboes K, Riddell R, Öst A, et al. A reproducible grading scale for histological assessment of inflammation in ulcerative colitis. Gut 2000 47 : 404 9.
23. Berg EL, Robinson MK, Mansson O, et al. A carbohydrate domain common to both sialyl Lea and sialyl LeX is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. J Biol Chem 1991 266 : 14869 72.
24. Jones D, O'Hara C, Kraus MD, et al. Expression pattern of T-cell-associated chemokine receptors and their chemokines correlates with specific subtypes of T-cell non-Hodgkin lymphoma. Blood 2000 96 : 685 90.
25. Tsuchiya T, Ohshima K, Karube K, et al. Th1, Th2, and activated T-cell marker and clinical prognosis in peripheral T-cell lymphoma, unspecified: Comparison with AILD, ALCL, lymphoblastic lymphoma, and ATLL. Blood 2004 103 : 236 41.
26. Lohning M, Stroehmann A, Coyle AJ, et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci U S A 1998 95 : 6930 5.
27. Day DW, Jass JR, Price AB, et al. Morson and Dawson's gastrointestinal pathology, 4th Ed. Oxford : Blackwell, 2003.
28. Specht K, Richter T, Muller U, et al. Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue. Am J Pathol 2001 158 : 419 29.
29. Uchimura K, Muramatsu H, Kaname T, et al. Human N-acetylglucosamine-6-O- sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: Molecular cloning, chromosomal mapping, and expression in various organs and tumor cells. J Biochem (Tokyo) 1998 124 : 670 8.
30. Hiraoka N, Petryniak B, Nakayama J, et al. A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl LewisX, an L-selectin ligand displayed by CD34. Immunity 1999 11 : 79 89.
31. Uchimura K, Gauguet JM, Singer MS, et al. A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol 2005 6 : 1105 13.
32. Dixon MF, Genta RM, Yardley JH, et al. Classification and grading of gastritis. The updated Sydney system. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996 20 : 1161 81.
33. Kawashima H, Petryniak B, Hiraoka N, et al. N-acetylglucosamine-6-O- sulfotransferase 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules. Nat Immunol 2005 6 : 1096 104.
34. Drayton DL, Ying X, Lee J, et al. Ectopic LTαβ directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase. J Exp Med 2003 197 : 1153 63.
35. Van Assche G, Rutgeerts P. Physiological basis for novel drug therapies used to treat the inflammatory bowel diseases. I. Immunology and therapeutic potential of antiadhesion molecule therapy in inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol 2005 288 : G169 74.
36. Rosen SD, Tsay D, Singer MS, et al. Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma. Am J Pathol 2005 166 : 935 44.