Oligonucleotide analogues with integrated bases and backbone: Part 20 - Hydrazide- and amide-linked analogues. 1. Design and synthesis of monomeric building blocks

Helvetica Chimica Acta

Volumn 92, Issue 6, 2009, Pages 1134-1166

  Peifer, Manuel ^a   De Giacomo, Fabio ^a   Schandl, Martin ^a   Vasella, Andrea ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BUILDING BLOCK; CURTIUS DEGRADATION; CYCLISATION; NITROSO; NUCLEOPHILIC SUBSTITUTIONS; RAPID SYNTHESIS; WATER-SOLUBLE OLIGOMERS; WITTIG REACTION;

ALDEHYDES; AMIDES; CARBOXYLIC ACIDS; NITROGEN COMPOUNDS; OLIGOMERS; OLIGONUCLEOTIDES; ORGANIC ACIDS;

SYNTHESIS (CHEMICAL);

2,6 DIAMINO 4 (BENZYLOXY) 5 NITROSOPYRIMIDINE; 3 [1 [[(TERT BUTOXY)CARBONYL]METHYL]URACIL 6 YL]PROPANOIC ACID; 3 [N 4 [(BENZYLOXY)CARBONYL] 1 [[(TERT BUTOXY)CARBONYL]METHYL]CYTOSIN 6 YL]PROPANOIC ACID; 3 [N 6 [(BENZYLOXY)CARBONYL] 9 [[(TERT BUTOXY)CARBONYL]METHYL]ADENIN 8 YL]PROPANOIC ACID; 6 (ACYLAMINO) 5 NITROSOPYRIMIDINE; 6 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]URACIL 1 ACETIC ACID; 8 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]GUANINE 9 ACETIC ACID; 8 [[1 (2 ETHOXY 2 OXOETHYL) 2 [[(9H FLUOREN 9 YL)METHOXY]CARBONYL]HYDRAZINO]METHYL]GUANINE 9 ACETIC ACID; AMIDE; HYDRAZIDE; HYDRAZINOACETATE; METHYL 3 [N 4 [(BENZYLOXY)CARBONYL] 1 [[(TERT BUTOXY)CARBONYL]METHYL]CYTOSIN 6 YL]PROP 2 ENOATE; METHYL 3 [N 4 [(BENZYLOXY)CARBONYL] 1 [[(TERT BUTOXY)CARBONYL]METHYL]CYTOSINE 6 YL]PROPANOATE; METHYL 3 [N 6 [(BENZYLOXY)CARBONYL] 9 [[(TERT BUTOXY)CARBONYL]METHYL]ADENIN 8 YL]PROPANOATE; METHYL 3 [N 6 [(BENZYLOXY)CARBONYL] 9 [[(TERT BUTOXY)CARBONYL]METHYL]ADENINE 8 YL]PROP 2 ENOATE; N 4 [(BENZYLOXY)CARBONYL] 6 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]CYTOSINE 1 ACETIC ACID; N 6 [(BENZYLOXY)CARBONYL] 8 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]ADENINE 9 ACETIC ACID; OLIGONUCLEOTIDE; TERT BUTYL 6 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]URACIL 1 ACETATE; TERT BUTYL 6 [[1 (2 ETHOXY 2 OXOETHYL) 2 [[(9H FLUOREN 9 YL)METHOXY]CARBONYL]HYDRAZINO]METHYL]URACIL 1 ACETATE; TERT BUTYL 6 O BENZYL 8 (2 PHTHALIMIDOETHYL)GUANINE 7 ACETATE; TERT BUTYL 6 O BENZYL 8 (2 PHTHALIMIDOETHYL)GUANINE 9 ACETATE; TERT BUTYL 6 O BENZYL 8 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]GUANINE 9 ACETATE; TERT BUTYL 8 (2 AMINOETHYL) 6 O BENZYLGUANINE 9 ACETATE; TERT BUTYL N 4 [(BENZYLOXY)CARBONYL] 6 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]CYTOSINE 1 ACETATE; TERT BUTYL N 4 [(BENZYLOXY)CARBONYL] 6 [[1 (2 ETHOXY 2 OXOETHYL) 2 [[(9H FLUOREN 9 YL)METHOXY]CARBONYL]HYDRAZINO]METHYL]CYTOSINE 1 ACETATE; TERT BUTYL N 4 [(BENZYLOXY)CARBONYL] 6 FORMYLCYTOSINE 1 ACETATE; TERT BUTYL N 6 [(BENZYLOXY)CARBONYL] 8 [2 [[[(9H FLUOREN 9 YL)METHOXY]CARBONYL]AMINO]ETHYL]ADENINE 9 ACETATE; TERT BUTYL N 6 [(BENZYLOXY)CARBONYL] 8 FORMYLADENINE 9 ACETATE; TERT BUTYL N 6 [(BENZYLOXY)CARBONYL]ADENINE 9 ACETATE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CURTIUS REARRANGEMENT; CYCLIZATION; PRIORITY JOURNAL; SUBSTITUTION REACTION; SYNTHESIS; WITTIG REACTION;

EID: 67649651709     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200900047     Document Type: Article

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