Characterization of lassa virus cell entry inhibitors: Determination of the active enantiomer by asymmetric synthesis

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 14, 2009, Pages 3771-3774

  Whitby, Landon R ^a   Lee, Andrew M ^a   Kunz, Stefan ^b   Oldstone, Michael B A ^a   Boger, Dale L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Lassa fever virus; Viral entry inhibitors

Indexed keywords

LASSAMYCIN 1; PIPERAZINE DERIVATIVE; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

ARENAVIRUS; ARTICLE; ASYMMETRIC SYNTHESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; ENANTIOMER; IC 50; LASSA VIRUS; NONHUMAN; VIRUS ENTRY; VIRUS HEMORRHAGIC FEVER; VIRUS INHIBITION;

ANTIVIRAL AGENTS; BENZOFURANS; CELL LINE, TUMOR; HUMANS; LASSA VIRUS; PIPERAZINES; STEREOISOMERISM; VIRUS INTERNALIZATION;

ARENAVIRUS; LASSA VIRUS;

EID: 67649644628     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.04.098     Document Type: Article

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