Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses

Journal of Biological Chemistry

Volumn 283, Issue 27, 2008, Pages 18734-18742

  Lee, Andrew M ^a   Rojek, Jillian M ^a   Spiropoulou, Christina F ^b   Gundersen, Anette T ^a   Jin, Wei ^a   Shaginian, Alex ^a   York, Joanne ^c   Nunberg, Jack H ^c   Boger, Dale L ^a   Oldstone, Michael B A ^a   Kunz, Stefan ^a,d  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c UNIVERSITY OF MONTANA   (United States)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; LEAD COMPOUNDS; MOLECULES; PROTEINS; SATELLITE NAVIGATION AIDS;

ENVELOPED VIRUSES; FATALITY RATES; HIGH THROUGHPUT SCREENINGS; HUMAN DISEASES; MECHANISM OF ACTIONS; MEMBRANE FUSIONS; OLD WORLDS; POTENT INHIBITIONS; SMALL MOLECULES; SOUTH AMERICA; VIRAL FUSION PROTEINS;

VIRUSES;

ANTIVIRUS AGENT; BENZOFURAN DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; HYBRID PROTEIN; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; VIRUS GLYCOPROTEIN; VIRUS FUSION PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARENAVIRUS; ARTICLE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG POTENCY; EBOLA VIRUS; GUANARITO VIRUS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; JUNIN VIRUS; LASSA VIRUS; MACHUPO ARENAVIRUS; MEMBRANE FUSION; NONHUMAN; PH; PHYLOGENY; PRIMATE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VESICULAR STOMATITIS VIRUS; VIRUS PARTICLE; VIRUS TYPING; WHITEWATER ARROYO VIRUS; ANIMAL; CERCOPITHECUS; CHEMISTRY; COMMUNICABLE DISEASE; DRUG ANTAGONISM; DRUG SCREENING; HELA CELL; METABOLISM; VERO CELL; VIRION; VIRUS HEMORRHAGIC FEVER; VIRUS INFECTION;

ARENAVIRUS; LASSA VIRUS; PRIMATES; SABIA VIRUS;

ANIMALS; ANTIVIRAL AGENTS; ARENAVIRIDAE INFECTIONS; ARENAVIRUS; CERCOPITHECUS AETHIOPS; COMMUNICABLE DISEASES, EMERGING; DRUG EVALUATION, PRECLINICAL; HELA CELLS; HEMORRHAGIC FEVERS, VIRAL; HUMANS; VERO CELLS; VIRAL FUSION PROTEINS; VIRION;

EID: 49649122323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802089200     Document Type: Article

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