Molecular variability of FLT3/ITD mutants and their impact on the differentiation program of 32D cells: Implications for the biological properties of AML blasts

Leukemia Research

Volumn 33, Issue 10, 2009, Pages 1409-1416

  Pekova, Sona ^a   Ivanek, Robert ^b   Dvorak, Michal ^b   Rueggeberg, Sabrina ^c   Leicht, Stefan ^c   Li, Xinping ^c   Franz, Thomas ^c   Kozak, Tomas ^d   Vrba, Jiri ^d   Koza, Vladimir ^e   Karas, Michal ^e   Schwarz, Jiri ^f   Cetkovsky, Petr ^f   Prucha, Miroslav ^a  

^a NA HOMOLCE HOSPITAL   (Czech Republic)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c Proteomics Core Facility   (Germany)

^d CHARLES UNIVERSITY   (Czech Republic)

^e CHARLES UNIVERSITY   (Czech Republic)

^f INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

AML; FLT3 ITD; Hematopoiesis; Microarrays; Proteomics

Indexed keywords

CD135 ANTIGEN; MUTANT PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BLAST CELL; BONE MARROW CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL STRAIN 32D; CONTROLLED STUDY; GENE DUPLICATION; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; TWO DIMENSIONAL ELECTROPHORESIS;

AMINO ACID SEQUENCE; ANIMALS; BLAST CRISIS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; CLONING, MOLECULAR; EXONS; FMS-LIKE TYROSINE KINASE 3; GENE EXPRESSION PROFILING; GENETIC VARIATION; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TANDEM REPEAT SEQUENCES;

EID: 67649550136     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.01.004     Document Type: Article

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