Deciphering developmental stages of adult myelopoiesis

Cell Cycle

Volumn 7, Issue 6, 2008, Pages 706-713

  Pronk, Cornelis J ^a   Attema, Joanne ^a   Rossi, Derrick J ^b   Sigvardsson, Mikael ^c   Bryder, David ^a  

^a LUND UNIVERSITY   (Sweden)

^b HARVARD MEDICAL SCHOOL   (United States)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Gene expression; Hematopoiesis; Hematopoietic stem cell; Lineage commitment; Lineage potential; Myeloid precursor; Myeloid progenitor

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTOME;

APOPTOSIS; CELL LINEAGE; ERYTHROID PRECURSOR CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC ASSOCIATION; GRANULOCYTE; HEMATOPOIETIC STEM CELL; LYMPHOPOIESIS; MEGAKARYOCYTE; MONOCYTE; MYELOID PROGENITOR CELL; MYELOPOIESIS; NONHUMAN; PROTEIN EXPRESSION; REVIEW;

EID: 42049120265     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.6.5565     Document Type: Review

References (37)

1. Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988; 241:58-62.
2. Bryder D, Rossi DJ, Weissman IL. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol 2006; 169:338-46.
3. Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996; 273:242-5.
4. Chen CZ, Li M, de Graaf D, Monti S, Gottgens B, Sanchez MJ, Lander ES, Golub TR, Green AR, Lodish HF. Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells. Proc Natl Acad Sci USA 2002; 99:15468-73.
5. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005; 121:1109-21.
6. Moody JL, Singbrant S, Karlsson G, Blank U, Aspling M, Flygare J, Bryder D, Karlsson S. Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development. Stem Cells 2007; 25:2809-19.
7. Cross MA, Enver T. The lineage commitment of haemopoietic progenitor cells. Curr Opin Genet Dev 1997; 7:609-13.
8. Nygren JM, Bryder D, Jacobsen SE. Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property. J Immunol 2006; 177:201-8.
9. Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997; 91:661-72.
10. Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000; 404:193-7.
11. Iwasaki H, Akashi K. Myeloid lineage commitment from the hematopoietic stem cell. Immunity 2007; 26:726-40.
12. Nakorn TN, Miyamoto T, Weissman IL. Characterization of mouse clonogenic megakaryocyte progenitors. Proc Natl Acad Sci USA 2003; 100:205-10.
13. Iwasaki H, Somoza C, Shigematsu H, Duprez EA, Iwasaki-Arai J, Mizuno S, Arinobu Y, Geary K, Zhang P, Dayaram T, Fenyus ML, Elf S, Chan S, Kastner P, Huettner CS, Murray R, Tenen DG, Akashi K. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood 2005; 106:1590-600.
14. Christensen JL, Weissman IL. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc Natl Acad Sci USA 2001; 98:14541-6.
15. + lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 2005; 121:295-306.
16. Lai AY, Kondo M. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J Exp Med 2006; 203:1867-73.
17. Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994; 265:1573-7.
18. Nutt SL, Metcalf D, D'Amico A, Polli M, Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med 2005; 201:221-31.
19. + multipotent hematopoietic progenitors. Cell 2006; 126:415-26.
20. Pronk CJH, Rossi DJ, Månsson R, Attema LJ, Norddahl GL, Chan CKF, Sigvardsson M, Weissman IL, D B. Elucidation of the phenotypic, functional and molecular topography of a myeloerythroid progenitor cell hierarchy. . Cell Stem Cell 2007; 1:428-42.
21. Enver T, Heyworth CM, Dexter TM. Do stem cells play dice? Blood 1998; 92:348-51; discussion 52.
22. Domen J, Weissman IL. Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J Exp Med 2000; 192:1707-18.
23. Miyamoto T, Iwasaki H, Reizis B, Ye M, Graf T, Weissman IL, Akashi K. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell 2002; 3:137-47.
24. Akashi K, He X, Chen J, Iwasaki H, Niu C, Steenhard B, Zhang J, Haug J, Li L. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 2003; 101:383-9.
25. Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002; 297:2256-9.
26. + CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential. Eur J Immunol 2005; 35:2019-30.
27. Deshpande AJ, Buske C. Lymphoid progenitors as candidate cancer stem cells in AML: new perspectives. Cell Cycle 2007; 6:543-5.
28. Blais A, Dynlacht BD. Constructing transcriptional regulatory networks. Genes Dev 2005; 19:1499-511.
29. Bottardi S, Ghiam AF, Bergeron F, Milot E. Lineage-specific transcription factors in multipotent hematopoietic progenitors: a little bit goes a long way. Cell Cycle 2007; 6:1035-9.
30. Grass JA, Jing H, Kim SI, Martowicz ML, Pal S, Blobel GA, Bresnick EH. Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Mol Cell Biol 2006; 26:7056-67.
31. Lam LT, Ronchini C, Norton J, Capobianco AJ, Bresnick EH. Suppression of erythroid but not megakaryocytic differentiation of human K562 erythroleukemic cells by notch-1. J Biol Chem 2000; 275:19676-84.
32. Tagoh H, Ingram R, Wilson N, Salvagiotto G, Warren AJ, Clarke D, Busslinger M, Bonifer C. The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction. Embo J 2006; 25:1070-80.
33. Heavey B, Charalambous C, Cobaleda C, Busslinger M. Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors. Embo J 2003; 22:3887-97.
34. Benveniste P, Cantin C, Hyam D, Iscove NN. Hematopoietic stem cells engraft in mice with absolute efficiency. Nat Immunol 2003; 4:708-13.
35. Domen J, Gandy KL, Weissman IL. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 1998; 91:2272-82.
36. Metcalf D. Blood Lines - an Introduction to Characterizing Blood Diseases of the Post-Genomic Mouse. AlphaMed Press 2004.
37. Irizarry RA, Hobbs B, Collin F, Beazer Barclay YD, Antonellis KJ, Scherf U, Speed TP. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4:249-64.