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Volumn 386, Issue 2, 2009, Pages 356-362

Activation of AMP-activated protein kinase mediates acute and severe hypoxic injury to pancreatic beta cells

Author keywords

AMP activated protein kinase; Hypoxia; Islet transplantation; Oxidative stress

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYLCYSTEINE; CASPASE 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; REACTIVE OXYGEN METABOLITE;

EID: 67649447250     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.039     Document Type: Article
Times cited : (19)

References (35)
  • 1
    • 1442265579 scopus 로고    scopus 로고
    • Islet transplantation as a treatment for diabetes - a work in progress
    • Robertson R.P. Islet transplantation as a treatment for diabetes - a work in progress. N. Engl. J. Med. 350 (2004) 694-705
    • (2004) N. Engl. J. Med. , vol.350 , pp. 694-705
    • Robertson, R.P.1
  • 2
  • 3
    • 0036097472 scopus 로고    scopus 로고
    • Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia
    • Biarnes M., Montolio M., Nacher V., Raurell M., Soler J., and Montanya E. Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 51 (2002) 66-72
    • (2002) Diabetes , vol.51 , pp. 66-72
    • Biarnes, M.1    Montolio, M.2    Nacher, V.3    Raurell, M.4    Soler, J.5    Montanya, E.6
  • 4
    • 18244364592 scopus 로고    scopus 로고
    • Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts
    • Barshes N.R., Wyllie S., and Goss J.A. Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts. J. Leukoc. Biol. 77 (2005) 587-597
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 587-597
    • Barshes, N.R.1    Wyllie, S.2    Goss, J.A.3
  • 5
    • 0036889475 scopus 로고    scopus 로고
    • Oxygen deprivation induced cell death: an update
    • Brunelle J.K., and Chandel N.S. Oxygen deprivation induced cell death: an update. Apoptosis 7 (2002) 475-482
    • (2002) Apoptosis , vol.7 , pp. 475-482
    • Brunelle, J.K.1    Chandel, N.S.2
  • 7
    • 0036933569 scopus 로고    scopus 로고
    • Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants
    • Carlsson P.O., and Palm F. Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants. Transpl. Int. 15 (2002) 581-585
    • (2002) Transpl. Int. , vol.15 , pp. 581-585
    • Carlsson, P.O.1    Palm, F.2
  • 8
    • 0026446002 scopus 로고
    • Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts
    • Menger M.D., Vajkoczy P., Leiderer R., Jager S., and Messmer K. Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts. J. Clin. Invest. 90 (1992) 1361-1369
    • (1992) J. Clin. Invest. , vol.90 , pp. 1361-1369
    • Menger, M.D.1    Vajkoczy, P.2    Leiderer, R.3    Jager, S.4    Messmer, K.5
  • 10
    • 0035313697 scopus 로고    scopus 로고
    • HIF-1 and mechanisms of hypoxia sensing
    • Semenza G.L. HIF-1 and mechanisms of hypoxia sensing. Curr. Opin. Cell Biol. 13 (2001) 167-171
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 167-171
    • Semenza, G.L.1
  • 11
  • 12
    • 40049111236 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase-nitric oxide plays an important role in acute and severe hypoxic injury to pancreatic beta cells
    • Ko S.H., Ryu G.R., Kim S., Ahn Y.B., Yoon K.H., Kaneto H., Ha H., Kim Y.S., and Song K.H. Inducible nitric oxide synthase-nitric oxide plays an important role in acute and severe hypoxic injury to pancreatic beta cells. Transplantation 85 (2008) 323-330
    • (2008) Transplantation , vol.85 , pp. 323-330
    • Ko, S.H.1    Ryu, G.R.2    Kim, S.3    Ahn, Y.B.4    Yoon, K.H.5    Kaneto, H.6    Ha, H.7    Kim, Y.S.8    Song, K.H.9
  • 14
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • Long Y.C., and Zierath J.R. AMP-activated protein kinase signaling in metabolic regulation. J. Clin. Invest. 116 (2006) 1776-1783
    • (2006) J. Clin. Invest. , vol.116 , pp. 1776-1783
    • Long, Y.C.1    Zierath, J.R.2
  • 15
    • 0038584871 scopus 로고    scopus 로고
    • Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
    • da Silva Xavier G., Leclerc I., Varadi A., Tsuboi T., Moule S.K., and Rutter G.A. Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression. Biochem. J. 371 (2003) 761-774
    • (2003) Biochem. J. , vol.371 , pp. 761-774
    • da Silva Xavier, G.1    Leclerc, I.2    Varadi, A.3    Tsuboi, T.4    Moule, S.K.5    Rutter, G.A.6
  • 16
    • 28044464932 scopus 로고    scopus 로고
    • Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo
    • Richards S.K., Parton L.E., Leclerc I., Rutter G.A., and Smith R.M. Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo. J. Endocrinol. 187 (2005) 225-235
    • (2005) J. Endocrinol. , vol.187 , pp. 225-235
    • Richards, S.K.1    Parton, L.E.2    Leclerc, I.3    Rutter, G.A.4    Smith, R.M.5
  • 17
    • 0038363852 scopus 로고    scopus 로고
    • AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase
    • Kefas B.A., Cai Y., Ling Z., Heimberg H., Hue L., Pipeleers D., and Van de Casteele M. AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase. J. Mol. Endocrinol. 30 (2003) 151-161
    • (2003) J. Mol. Endocrinol. , vol.30 , pp. 151-161
    • Kefas, B.A.1    Cai, Y.2    Ling, Z.3    Heimberg, H.4    Hue, L.5    Pipeleers, D.6    Van de Casteele, M.7
  • 18
    • 0037301056 scopus 로고    scopus 로고
    • AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase
    • Kefas B.A., Heimberg H., Vaulont S., Meisse D., Hue L., Pipeleers D., and Van de Casteele M. AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase. Diabetologia 46 (2003) 250-254
    • (2003) Diabetologia , vol.46 , pp. 250-254
    • Kefas, B.A.1    Heimberg, H.2    Vaulont, S.3    Meisse, D.4    Hue, L.5    Pipeleers, D.6    Van de Casteele, M.7
  • 19
    • 33751549094 scopus 로고    scopus 로고
    • Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation
    • Cai Y., Martens G.A., Hinke S.A., Heimberg H., Pipeleers D., and Van de Casteele M. Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation. Free Radic. Biol. Med. 42 (2007) 64-78
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 64-78
    • Cai, Y.1    Martens, G.A.2    Hinke, S.A.3    Heimberg, H.4    Pipeleers, D.5    Van de Casteele, M.6
  • 20
    • 33747596652 scopus 로고    scopus 로고
    • Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia
    • Guzy R.D., and Schumacker P.T. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp. Physiol. 91 (2006) 807-819
    • (2006) Exp. Physiol. , vol.91 , pp. 807-819
    • Guzy, R.D.1    Schumacker, P.T.2
  • 21
    • 33845741242 scopus 로고    scopus 로고
    • The cellular basis for diverse responses to oxygen
    • Chandel N.S., and Budinger G.R. The cellular basis for diverse responses to oxygen. Free Radic. Biol. Med. 42 (2007) 165-174
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 165-174
    • Chandel, N.S.1    Budinger, G.R.2
  • 22
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: a breath of life or death?
    • Fruehauf J.P., and Meyskens Jr. F.L. Reactive oxygen species: a breath of life or death?. Clin. Cancer Res. 13 (2007) 789-794
    • (2007) Clin. Cancer Res. , vol.13 , pp. 789-794
    • Fruehauf, J.P.1    Meyskens Jr., F.L.2
  • 23
  • 24
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared to with various other mouse tissues
    • Lenzen S., Drinkgern J., and Tiedge M. Low antioxidant enzyme gene expression in pancreatic islets compared to with various other mouse tissues. Free Radic. Biol. Med. 320 (1996) 463-466
    • (1996) Free Radic. Biol. Med. , vol.320 , pp. 463-466
    • Lenzen, S.1    Drinkgern, J.2    Tiedge, M.3
  • 25
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus
    • Staal F.J., Roederer M., Herzenberg L.A., and Herzenberg L.A. Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 87 (1990) 9943-9947
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9943-9947
    • Staal, F.J.1    Roederer, M.2    Herzenberg, L.A.3    Herzenberg, L.A.4
  • 26
    • 0141960109 scopus 로고    scopus 로고
    • AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
    • Lee M., Hwang J.T., Lee H.J., Jung S.N., Kang I., Chi S.G., Kim S.S., and Ha J. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J. Biol. Chem. 278 (2003) 39653-39661
    • (2003) J. Biol. Chem. , vol.278 , pp. 39653-39661
    • Lee, M.1    Hwang, J.T.2    Lee, H.J.3    Jung, S.N.4    Kang, I.5    Chi, S.G.6    Kim, S.S.7    Ha, J.8
  • 27
    • 37049033241 scopus 로고    scopus 로고
    • Transcriptional mechanism of suppression of insulin gene expression by AMP-activated protein kinase activator 5-amino-4-imidazolecarboxamide riboside (AICAR) in beta-cells
    • Kim J.W., Cho J.H., Ko S.H., Park H.S., Ha J., Song K.H., Son H.Y., Kim S.S., Yoon K.H., and Suh-Kim H. Transcriptional mechanism of suppression of insulin gene expression by AMP-activated protein kinase activator 5-amino-4-imidazolecarboxamide riboside (AICAR) in beta-cells. Biochem. Biophys. Res. Commun. 365 (2008) 614-620
    • (2008) Biochem. Biophys. Res. Commun. , vol.365 , pp. 614-620
    • Kim, J.W.1    Cho, J.H.2    Ko, S.H.3    Park, H.S.4    Ha, J.5    Song, K.H.6    Son, H.Y.7    Kim, S.S.8    Yoon, K.H.9    Suh-Kim, H.10
  • 29
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function
    • Davalli A.M., Scaglia L., Zangen D.H., Hollister J., Bonner-Weir S., and Weir G.C. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45 (1996) 1161-1167
    • (1996) Diabetes , vol.45 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 30
    • 0027470723 scopus 로고
    • Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans
    • Dionne K.E., Colton C.K., and Yarmuch M.L. Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes 42 (1993) 12-21
    • (1993) Diabetes , vol.42 , pp. 12-21
    • Dionne, K.E.1    Colton, C.K.2    Yarmuch, M.L.3
  • 32
  • 33
    • 0036328572 scopus 로고    scopus 로고
    • Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound
    • Bottino R., Balamurugan A.N., Bertera S., Pietropaolo M., Trucco M., and Piganelli J.D. Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound. Diabetes 51 (2002) 2561-2567
    • (2002) Diabetes , vol.51 , pp. 2561-2567
    • Bottino, R.1    Balamurugan, A.N.2    Bertera, S.3    Pietropaolo, M.4    Trucco, M.5    Piganelli, J.D.6


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