Changes of hepatic proteome in bile duct ligated rats with hepatic fibrosis following treatment with Yin-Chen-Hao-Tang

International Journal of Molecular Medicine

Volumn 23, Issue 4, 2009, Pages 477-484

  Lee, Tzung Yan ^a   Chang, Hen Hong ^a,b   Kuo, Jong Jen ^b   Shen, Jiann Jong ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Hepatic fibrosis; Proteomics; Yin Chen Hao Tang

Indexed keywords

APOLIPOPROTEIN A1; ARTEMISIA CAPILLARIS EXTRACT; CAPILLARISIN; CHINESE DRUG; CYTOKERATIN 8; CYTOKERATIN 9; DYNEIN ADENOSINE TRIPHOSPHATASE; EMODIN; GARDENIA JASMINOIDES EXTRACT; GENIPOSIDE; LIVER PROTEIN; MEGALIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PLANT MEDICINAL PRODUCT; PLECTIN; REGUCALCIN; RHEUM OFFICINALE EXTRACT; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; YIN CHEN HAO TANG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; LIPID METABOLISM; LIVER FIBROSIS; LIVER PROTECTION; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION;

ANIMALS; ARTEMISIA; BILE DUCTS; BLOOD PROTEINS; DRUG COMBINATIONS; DRUGS, CHINESE HERBAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GARDENIA; GENE EXPRESSION; LIGATION; LIVER; LIVER CIRRHOSIS; MATRIX METALLOPROTEINASE 2; PROTEOME; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHEUM; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 67649429275     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000154     Document Type: Article

References (21)

1. Friedman SL: Liver fibrosis - from bench to bedside. J Hepatol 38: S38-S53, 2003.
2. Arthur MJ: Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol 279: G245-G249, 2000.
3. Anderson NL, Esquer-Blasco R, Richardson F, Foxworthy P and Eacho P: The effects of peroxisome proliferators on protein abundances in mouse liver. Toxicol Appl Pharmacol 137: 75-89, 1996.
4. Arce A, Aicher L, Wahl D, et al: Changes in the liver protein pattern of female Wistar rats treated with the hypoglycemic agent SDZ PGU 693. Life Sci 63: 2243-2250, 1998.
5. Fountoulakis M, Berndt P, Boelsterli UA, Crameri F, Winter M, Albertini S and Suter L: Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol. Electrophoresis 21: 2148-2161, 2000.
6. Fountoulakis M, De Vera MC, Crameri F, Boess F, Gasser R, Albertini S and Suter L: Modulation of gene and protein expression by carbon tetrachloride in the rat liver. Toxicol Appl Pharmacol 183: 71-80, 2002.
7. Sakaida I, Tsuchiya M, Kawaguchi K, Kimura T, Terai S and Okita K: Herbal medicine Inchin-ko-to (TJ-135) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. J Hepatol 38: 762-769, 2003.
8. Inao M, Mochida S, Matsui A, et al: Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis. J Hepatol 41: 584-591, 2004.
9. Imanishi Y, Maeda N, Otogawa K, Seki S, Matsui H, Kawada N and Arakawa T: Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats. J Hepatol 41: 242-250, 2004.
10. Lee TY, Chang HH, Chen JH, Hsueh ML and Kuo JJ: Herb medicine Yin-Chen-Hao-Tang ameliorates hepatic fibrosis in bile duct ligation rats. J Ethnopharmacol 109: 318-324, 2007.
11. Yamamoto M, Ogawa K, Morita M, Fukuda K and Komatsu Y: The herbal medicine Inchin-ko-to inhibits liver cell apoptosis induced by transforming growth factor beta 1. Hepatology 23: 552-559, 1996.
12. Yamamoto M, Miura N, Ohtake N, et al: Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice. Gastroenterology 118: 380-389, 2000.
13. Lee TY, Chang HH, Wu MY and Lin HC: Yin-Chen-Hao-Tang ameliorates obstruction-induced hepatic apoptosis in rats. J Pharm Pharmacol 59: 583-590, 2007.
14. He QY, Lau GK, Zhou Y, Yuen ST, Lin MC, Kung HF and Chiu JF: Serum biomarkers of hepatitis B virus infected liver inflammation: a proteomic study. Proteomics 3: 666-674, 2003.
15. Steel LF, Shumpert D, Trotter M, et al: A strategy for the comparative analysis of serum proteomes for the discovery of biomarkers for hepatocellular carcinoma. Proteomics 3: 601-609, 2003.
16. Sadrzadeh SM and Bozorgmehr J: Haptoglobin phenotypes in health and disorders. Am J Clin Pathol 121: S97-S104, 2004.
17. McLean WH, Pulkkinen L, Smith FJ, et al: Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization. Genes Dev 10: 1724-1735, 1996.
18. Moll R, Franke WW, Schiller DL, Geiger B and Krepler R: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31: 11-24, 1982.
19. Kobayashi H, Narumi S, Tamatani T, Lane GJ and Miyano T: Serum IFN-inducible protein-10: a new clinical prognostic predictor of hepatocyte death in biliary atresia. J Pediatr Surg 34: 308-311, 1999.
20. MacFarlane M, Merrison W, Dinsdale D and Cohen GM: Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J Cell Biol 148: 1239-1254, 2000.
21. Fickert P, Trauner M, Fuchsbichler A, Stumptner C, Zatloukal K and Denk H: Cytokeratins as targets for bile acid-induced toxicity. Am J Physiol 160: G491-G499, 2002.