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Volumn 53, Issue 2, 2009, Pages 288-292

The N363S polymorphism in the glucocorticoid receptor gene: Effects on visceral fat assessed by abdominal computed tomography;Polimorfismo N363S do gene do receptor de glucocorticoide: Efeito sobre a adiposidade visceral medida pela tomografia computadorizada

Author keywords

Glucocorticoid; Metabolic syndrome; Obesity; Polymorphism

Indexed keywords


EID: 67649413359     PISSN: 00042730     EISSN: 16779487     Source Type: Journal    
DOI: 10.1590/S0004-27302009000200021     Document Type: Article
Times cited : (5)

References (31)
  • 1
    • 0030144120 scopus 로고    scopus 로고
    • Inhibition of cortisol secretion by dexamethasone in relation to body fat distribution: A dose-response study
    • Ljung T, Andersson B, Bengtsson BA, Bjorntorp P, Marin P. Inhibition of cortisol secretion by dexamethasone in relation to body fat distribution: a dose-response study. Obes Res. 1996;4(3):277-82.
    • (1996) Obes Res , vol.4 , Issue.3 , pp. 277-282
    • Ljung, T.1    Andersson, B.2    Bengtsson, B.A.3    Bjorntorp, P.4    Marin, P.5
  • 2
    • 0033776719 scopus 로고    scopus 로고
    • Obesity and cortisol
    • Bjorntorp P, Rosmond R. Obesity and cortisol. Nutrition. 2000;16:924-36.
    • (2000) Nutrition , vol.16 , pp. 924-936
    • Bjorntorp, P.1    Rosmond, R.2
  • 3
    • 33846369850 scopus 로고    scopus 로고
    • Molecular aspects of glucocorticoid sensitivity
    • Faria CD, Longui CA. Molecular aspects of glucocorticoid sensitivity. Arq Bras Endocrinol Metabol. 2006;50(6):983-95.
    • (2006) Arq Bras Endocrinol Metabol , vol.50 , Issue.6 , pp. 983-995
    • Faria, C.D.1    Longui, C.A.2
  • 4
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans RM. The steroid and thyroid hormone receptor superfamily. Science. 1988;240:889-95.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 5
    • 0037248247 scopus 로고    scopus 로고
    • Update on glucocorticoid action and resistance
    • Leung DY, Bloom JW. Update on glucocorticoid action and resistance. J Allergy Clin Immunol. 2003;111:3-22.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 3-22
    • Leung, D.Y.1    Bloom, J.W.2
  • 6
    • 0030943735 scopus 로고    scopus 로고
    • Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance
    • Koper JW, Stolk RP, de Lange P, Huizenga NA, Molijn GJ, Pols HA, et al. Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance. Hum Genet. 1997;99:663-8.
    • (1997) Hum Genet , vol.99 , pp. 663-668
    • Koper, J.W.1    Stolk, R.P.2    de Lange, P.3    Huizenga, N.A.4    Molijn, G.J.5    Pols, H.A.6
  • 7
    • 34547777486 scopus 로고    scopus 로고
    • Molecular evidence for a link between the N363S glucocorticoid receptor polymorphism and altered gene expression
    • Jewell CM, Cidlowski JA. Molecular evidence for a link between the N363S glucocorticoid receptor polymorphism and altered gene expression. J Clin Endocrinol Metab. 2007;92(8):3268-77.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.8 , pp. 3268-3277
    • Jewell, C.M.1    Cidlowski, J.A.2
  • 8
    • 15144360854 scopus 로고    scopus 로고
    • A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo
    • Huizenga NA, Koper JW, De Lange P, Pols HA, Stolk RP, Burger H, et al. A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo. J Clin Endocrinol Metab. 1998;83:144-51.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 144-151
    • Huizenga, N.A.1    Koper, J.W.2    de Lange, P.3    Pols, H.A.4    Stolk, R.P.5    Burger, H.6
  • 9
    • 0033589793 scopus 로고    scopus 로고
    • High penetrance, overweight, and glucocorticoid receptor variant: Case-control study
    • Lin RC, Wang WY, Morris BJ. High penetrance, overweight, and glucocorticoid receptor variant: case-control study. BMJ. 1999;319:1337-8.
    • (1999) BMJ , vol.319 , pp. 1337-1338
    • Lin, R.C.1    Wang, W.Y.2    Morris, B.J.3
  • 10
    • 0038095669 scopus 로고    scopus 로고
    • The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients
    • Di Blasio AM, van Rossum EF, Maestrini S, Maestrini S, Berselli ME, Tagliaferri M, et al. The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients. Clin Endocrinol. 2003;59:68-74.
    • (2003) Clin Endocrinol , vol.59 , pp. 68-74
    • di Blasio, A.M.1    van Rossum, E.F.2    Maestrini, S.3    Maestrini, S.4    Berselli, M.E.5    Tagliaferri, M.6
  • 11
    • 0041664880 scopus 로고    scopus 로고
    • The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus
    • Roussel R, Reis AF, Dubois-Laforgue D, Bellanne-Chantelot C, Timsit J, Velho G. The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus. Clin Endocrinol. 2003;59:237-41.
    • (2003) Clin Endocrinol , vol.59 , pp. 237-241
    • Roussel, R.1    Reis, A.F.2    Dubois-Laforgue, D.3    Bellanne-Chantelot, C.4    Timsit, J.5    Velho, G.6
  • 12
    • 0034769251 scopus 로고    scopus 로고
    • The Asn363-Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men
    • Echwald SM, Sorensen TI, Andersen T, Pedersen O. The Asn363-Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men. Int J Obes Relat Metab Disord. 2001;25:1563-5.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 1563-1565
    • Echwald, S.M.1    Sorensen, T.I.2    Andersen, T.3    Pedersen, O.4
  • 13
    • 0035901268 scopus 로고    scopus 로고
    • Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: Cohort study
    • Rosmond R, Bouchard C, Bjorntorp P. Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: cohort study. BMJ. 2001;322:652-3.
    • (2001) BMJ , vol.322 , pp. 652-653
    • Rosmond, R.1    Bouchard, C.2    Bjorntorp, P.3
  • 14
    • 0035019845 scopus 로고    scopus 로고
    • The N363S polymorphism of the glucocorticoid receptor: Potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus
    • Dobson MG, Redfern CP, Unwin N, Weaver JU. The N363S polymorphism of the glucocorticoid receptor: potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus. J Clin Endocrinol Metab. 2001;86:2270-4.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2270-2274
    • Dobson, M.G.1    Redfern, C.P.2    Unwin, N.3    Weaver, J.U.4
  • 15
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
    • Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev. 2000;21:697-738.
    • (2000) Endocr Rev , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 16
    • 0023737723 scopus 로고
    • Regional body fat measurements with CT scan and evaluation of anthropometric predictions
    • Sjöström ML, Kvist H. Regional body fat measurements with CT scan and evaluation of anthropometric predictions. Acta Med Scand. 1988;723:169-77.
    • (1988) Acta Med Scand , vol.723 , pp. 169-177
    • Sjöström, M.L.1    Kvist, H.2
  • 17
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-9.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 18
    • 0037342601 scopus 로고    scopus 로고
    • Association of coronary artery disease with glucocorticoid receptor N363S variant
    • Lin RC, Wang XL, Morris BJ. Association of coronary artery disease with glucocorticoid receptor N363S variant. Hypertension. 2003;41:404-7.
    • (2003) Hypertension , vol.41 , pp. 404-407
    • Lin, R.C.1    Wang, X.L.2    Morris, B.J.3
  • 19
    • 0842334517 scopus 로고    scopus 로고
    • Low prevalence of the N363S polymorphism of the glucocorticoid receptor in South Asians living in the United Kingdom
    • Syed AA, Irving JA, Redfern CP, Hall AG, Unwin NC, White M, et al. Low prevalence of the N363S polymorphism of the glucocorticoid receptor in South Asians living in the United Kingdom. J Clin Endocrinol Metab. 2004;89:232-5.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 232-235
    • Syed, A.A.1    Irving, J.A.2    Redfern, C.P.3    Hall, A.G.4    Unwin, N.C.5    White, M.6
  • 21
    • 0032936343 scopus 로고    scopus 로고
    • Glucocorticoids and insulin resistance: Old hormones, new targets
    • Andrews RC, Walker BR. Glucocorticoids and insulin resistance: old hormones, new targets. Clin Sci. 1999;96:513-23.
    • (1999) Clin Sci , vol.96 , pp. 513-523
    • Andrews, R.C.1    Walker, B.R.2
  • 22
    • 0031846461 scopus 로고    scopus 로고
    • How to measure insulin sensitivity
    • Ferrannini E, Mari A. How to measure insulin sensitivity. J Hypertens. 1998;16:895-906.
    • (1998) J Hypertens , vol.16 , pp. 895-906
    • Ferrannini, E.1    Mari, A.2
  • 23
    • 33744494568 scopus 로고    scopus 로고
    • Laboratorial evaluation and diagnosis of insulin resistance
    • Geloneze B, Tambascia MA. Laboratorial evaluation and diagnosis of insulin resistance. Arq Bras Endocrinol Metabol. 2006;50:208-15.
    • (2006) Arq Bras Endocrinol Metabol , vol.50 , pp. 208-215
    • Geloneze, B.1    Tambascia, M.A.2
  • 24
    • 0033961701 scopus 로고    scopus 로고
    • Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: Studies in subjects with various degrees of glucose tolerance and insulin sensitivity
    • Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care. 2000;23:57-63.
    • (2000) Diabetes Care , vol.23 , pp. 57-63
    • Bonora, E.1    Targher, G.2    Alberiche, M.3    Bonadonna, R.C.4    Saggiani, F.5    Zenere, M.B.6
  • 25
    • 0030342776 scopus 로고    scopus 로고
    • Carbohydrate and lipid metabolism in endogenous hypercortisolism: Shared features with metabolic syndrome x and niddm
    • Friedman TC, Mastorakos G, Newman TD, Mullen NM, Horton EG, Costello R, et al. Carbohydrate and lipid metabolism in endogenous hypercortisolism: shared features with metabolic syndrome X and NIDDM. Endocr J. 1996;43:645-55.
    • (1996) Endocr J , vol.43 , pp. 645-655
    • Friedman, T.C.1    Mastorakos, G.2    Newman, T.D.3    Mullen, N.M.4    Horton, E.G.5    Costello, R.6
  • 27
    • 15844381594 scopus 로고    scopus 로고
    • Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
    • Shimomura I, Funahashi T, Takahashi M, Maeda K, Kotani K, Nakamura T, et al. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med. 1996;2:800-3.
    • (1996) Nat Med , vol.2 , pp. 800-803
    • Shimomura, I.1    Funahashi, T.2    Takahashi, M.3    Maeda, K.4    Kotani, K.5    Nakamura, T.6
  • 28
    • 0033323792 scopus 로고    scopus 로고
    • Hormonal control of plasminogen activator inhibitor-1 gene expression and production in human adipose tissue: Stimulation by glucocorticoids and inhibition by catecholamines
    • Halleux CM, Declerck PJ, Tran SL, Detry R, Brichard SM. Hormonal control of plasminogen activator inhibitor-1 gene expression and production in human adipose tissue: stimulation by glucocorticoids and inhibition by catecholamines. J Clin Endocrinol Metab. 1999;84:4097-105.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4097-4105
    • Halleux, C.M.1    Declerck, P.J.2    Tran, S.L.3    Detry, R.4    Brichard, S.M.5
  • 29
  • 30
    • 0024345761 scopus 로고
    • The hypertensive effect of synthetic glucocorticoids in man: Role of sodium and volume
    • Whitworth JA, Gordon D, Andrews J, Scoggins BA. The hypertensive effect of synthetic glucocorticoids in man: role of sodium and volume. J Hypertens. 1989;7:537-49.
    • (1989) J Hypertens , vol.7 , pp. 537-549
    • Whitworth, J.A.1    Gordon, D.2    Andrews, J.3    Scoggins, B.A.4
  • 31
    • 0030686447 scopus 로고    scopus 로고
    • Insulin as a vascular and sympathoexcitatory hormone: Implications for blood pressure regulation, insulin sensitivity, and cardiovascular morbidity
    • Scherrer U, Sartori C. Insulin as a vascular and sympathoexcitatory hormone: implications for blood pressure regulation, insulin sensitivity, and cardiovascular morbidity. Circulation. 1997;96:4104-13.
    • (1997) Circulation , vol.96 , pp. 4104-4113
    • Scherrer, U.1    Sartori, C.2


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