Influence of the Cyp1B1 L432V gene polymorphism and exposure to tobacco smoke on Cyp1B1 mRNA expression in human leukocytes

Drug Metabolism and Disposition

Volumn 37, Issue 7, 2009, Pages 1490-1495

  Helmig, Simone ^a   Hadzaad, Bahar ^a   Döhrel, Juliane ^a   Schneider, Joachim ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1B1; MESSENGER RNA; TOBACCO SMOKE;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; EXON; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MALE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SMOKING; SMOKING HABIT;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; ARYL HYDROCARBON HYDROXYLASES; FEMALE; GENE EXPRESSION; GENE FREQUENCY; HUMANS; LEUCINE; LEUKOCYTE COUNT; LEUKOCYTES; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; SMOKING; VALINE; YOUNG ADULT;

NICOTIANA TABACUM;

EID: 67649400449     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.027060     Document Type: Article

References (37)

1. Aklillu E, Oscarson M, Hidestrand M, Leidvik B, Otter C, and Ingelman-Sundberg M (2002) Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population. Mol Pharmacol 61:586-594. (Pubitemid 34171924)
2. Bailey LR, Roodi N, Dupont WD, and Parl FF (1998) Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer. Cancer Res 58:5038-5041. (Pubitemid 28521155)
3. Bartsch H, Nair U, Risch A, Rojas M, Wikman H, and Alexandrov K (2000) Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol Biomarkers Prev 9:3-28. (Pubitemid 30062906)
4. Brüning T, Abel J, Koch B, Lorenzen K, Harth V, Donat S, Sachinidis A, Vetter H, Bolt HM, and Ko Y (1999) Real-time PCR-analysis of the cytochrome P450 1B1 codon 432-polymorphism. Arch Toxicol 73:427-430. (Pubitemid 30010243)
5. Caporaso N and Goldstein A (1995) Cancer genes: single and susceptibility: exposing the difference. Pharmacogenetics 5:59-63.
6. Dassi C, Signorini S, Gerthoux P, Cazzaniga M, and Brambilla P (1998) Cytochrome P450 1B1 mRNA measured in blood mononuclear cells by quantitative reverse transcription-PCR. Clin Chem 44:2416-2421. (Pubitemid 28565651)
7. Engeland A (1996) Trends in the incidence of smoking-associated cancers in Norway, 1954-93. Int J Cancer 68:39-46. (Pubitemid 26354576)
8. Fritsche E, Brüning T, Jonkmanns C, Ko Y, Bolt HM, and Abel J (1999) Detection of cytochrome P450 1B1 Bfr I polymorphism: genotype distribution in healthy German individuals and in patients with colorectal carcinoma. Pharmacogenetics 9:405-408. (Pubitemid 29376387)
9. Furukawa M, Nishimura M, Ogino D, Chiba R, Ikai I, Ueda N, Naito S, Kuribayashi S, Moustafa MA, Uchida T, et al. (2004) Cytochrome p450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver. Cancer Sci 95:520-529. (Pubitemid 38832702)
10. Gorlova OY, Weng SF, Zhang Y, Amos CI, and Spitz MR (2007) Aggregation of cancer among relatives of never-smoking lung cancer patients. Int J Cancer 121:111-118. (Pubitemid 46753858)
11. Hanaoka T, Yamano Y, Pan G, Hara K, Ichiba M, Zhang J, Zhang S, Liu T, Li L, Takahashi K, et al. (2002) Cytochrome P450 1B1 mRNA levels in peripheral blood cells and exposure to polycyclic aromatic hydrocarbons in Chinese coke oven workers. Sci Total Environ 296:27-33. (Pubitemid 35286403)
12. Hu SW, Chen CC, Kuo CY, Lin WH, and Lin P (2006) Increased cytochrome P4501B1 gene expression in peripheral leukocytes of municipal waste incinerator workers. Toxicol Lett 160:112-120. (Pubitemid 41578954)
13. Kim JH, Sherman ME, Curriero FC, Guengerich FP, Strickland PT, and Sutter TR (2004) Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, nonsmokers, and ex-smokers. Toxicol Appl Pharmacol 199:210-219. (Pubitemid 39208722)
14. Ko Y, Abel J, Harth V, Bröde P, Antony C, Donat S, Fischer HP, Ortiz-Pallardo ME, Thier R, Sachinidis A, et al. (2001) Association of CYP1B1 codon 432 mutant allele in head and neck squamous cell cancer is reflected by somatic mutations of p53 in tumor tissue. Cancer Res 61:4398-4404. (Pubitemid 32685766)
15. Landi MT, Bergen AW, Baccarelli A, Patterson DG Jr, Grassman J, Ter-Minassian M, Mocarelli P, Caporaso N, Masten SA, Pesatori AC, et al. (2005) CYP1A1 and CYP1B1 genotypes, haplotypes, and TCDD-induced gene expression in subjects from Seveso, Italy. Toxicology 207:191-202. (Pubitemid 39642835)
16. Landi MT, Bertazzi PA, Baccarelli A, Consonni D, Masten S, Lucier G, Mocarelli P, Needham L, Caporaso N, and Grassman J (2003) TCDD-mediated alterations in the AhR-dependent pathway in Seveso, Italy, 20 years after the accident. Carcinogenesis 24:673-680. (Pubitemid 36592402)
17. Li DN, Seidel A, Pritchard MP, Wolf CR, and Friedberg T (2000) Polymorphisms in P450 CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol. Pharmacogenetics 10:343-353. (Pubitemid 30345182)
18. Lin P, Hu SW, and Chang TH (2003) Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes. Toxicol Sci 71:20-26. (Pubitemid 36163702)
19. McFadyen MC, Rooney PH, Melvin WT, and Murray GI (2003) Quantitative analysis of the Ah receptor/cytochrome P450 CYP1B1/CYP1A1 signalling pathway. Biochem Pharmacol 65:1663-1674. (Pubitemid 36577279)
20. Murray GI, Taylor MC, McFadyen MC, McKay JA, Greenlee WF, Burke MD, and Melvin WT (1997) Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 57:3026-3031. (Pubitemid 27315056)
21. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45.
22. Prescott E, Osler M, Andersen PK, Bjerg A, Hein HO, Borch-Johnsen K, Lange P, Schnohr P, and Vestbo J (1997) Has risk associated with smoking increased? Results from the Copenhagen Center for Prospective Population Studies. Int J Epidemiol 26:1214-1218. (Pubitemid 28010438)
23. Prescott E, Osler M, Andersen PK, Hein HO, Borch-Johnsen K, Lange P, Schnohr P, and Vestbo J (1998a) Mortality in women and men in relation to smoking. Int J Epidemiol 27:27-32. (Pubitemid 28140499)
24. Prescott E, Osler M, Hein HO, Borch-Johnsen K, Lange P, Schnohr P, and Vestbo J (1998b) Gender and smoking-related risk of lung cancer. The Copenhagen Center for Prospective Population Studies. Epidemiology 9:79-83.
25. Sasaki M, Tanaka Y, Okino ST, Nomoto M, Yonezawa S, Nakagawa M, Fujimoto S, Sakuragi N, and Dahiya R (2004) Polymorphisms of the CYP1B1 gene as risk factors for human renal cell cancer. Clin Cancer Res 10:2015-2019. (Pubitemid 38375561)
26. Sissung TM, Price DK, Sparreboom A, and Figg WD (2006) Pharmacogenetics and regulation of human cytochrome P450 1B1: implications in hormone-mediated tumor metabolism and a novel target for therapeutic intervention. Mol Cancer Res 4:135-150.
27. Spink DC, Spink BC, Cao JQ, DePasquale JA, Pentecost BT, Fasco MJ, Li Y, and Sutter TR (1998) Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis 19:291-298. (Pubitemid 28375423)
28. Sutter TR, Tang YM, Hayes CL, Wo YY, Jabs EW, Li X, Yin H, Cody CW, and Greenlee WF (1994) Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J Biol Chem 269:13092-13099. (Pubitemid 24206069)
29. Tang YM, Green BL, Chen GF, Thompson PA, Lang NP, Shinde A, Lin DX, Tan W, Lyn-Cook BD, Hammons GJ, et al. (2000) Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls. Pharmacogenetics 10:761-766. (Pubitemid 32042828)
30. Tuominen R, Warholm M, Möller L, and Rannug A (2003) Constitutive CYP1B1 mRNA expression in human blood mononuclear cells in relation to gender, genotype, and environmental factors. Environ Res 93:138-148. (Pubitemid 37083323)
31. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, and Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034.
32. van Duursen MB, Fernández Cantón R, Kocan T, Sanderson JT, Kieviet K, and van den Berg M (2005a) No effect of CYP1B1 Val432Leu polymorphism on CYP1B1 messenger RNA levels in an organochlorine-exposed population in Slovakia. Cancer Epidemiol Biomarkers Prev 14:755-756. (Pubitemid 40489230)
33. van Duursen MB, Sanderson JT, and van den Berg M (2005b) Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility. Toxicol Sci 85:703-712. (Pubitemid 40614300)
34. Wenzlaff AS, Cote ML, Bock CH, Land SJ, Santer SK, Schwartz DR, and Schwartz AG (2005) CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study. Carcinogenesis 26:2207-2212. (Pubitemid 41672209)
35. Willey JC, Coy EL, Frampton MW, Torres A, Apostolakos MJ, Hoehn G, Schuermann WH, Thilly WG, Olson DE, Hammersley JR, et al. (1997) Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers. Am J Respir Cell Mol Biol 17:114-124. (Pubitemid 127500828)
36. Wünsch Filho V and Zago MA (2005) Modern cancer epidemiological research: genetic polymorphisms and environment. Rev Saude Publica 39:490-497. (Pubitemid 41200562)
37. Zang EA and Wynder EL (1996) Differences in lung cancer risk between men and women: examination of the evidence. J Natl Cancer Inst 88:183-192. (Pubitemid 26065830)