Synthesis, antiviral and cytostatic evaluation of unsaturated exomethylene and keto D-lyxopyranonucleoside analogues

Archiv der Pharmazie

Volumn 342, Issue 6, 2009, Pages 353-360

  Tzioumaki, Niki ^a   Tsoukala, Evangelia ^a   Manta, Stella ^a   Agelis, George ^b   Balzarini, Jan ^c   Komiotis, Dimitri ^a  

^a UNIVERSITY OF THESSALY   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Cytotoxicity; Exomethylene nucleosides; Ketonucleosides; Unsaturated nucleosides

Indexed keywords

1 (2,3 O ISOPROPYLIDENE ALPHA DEXTRO LYXOPYRANOSYL)THYMINE; 1 (2,3 O ISOPROPYLIDENE ALPHA DEXTRO LYXOPYRANOSYL)URACIL; 1 (2,3,4 TRIDEOXY 4 METHYLENE ALPHA PENT 2 ENOPYRANOSYL)THYMINE; 1 (2,3,4 TRIDEOXY 4 METHYLENE ALPHA PENT 2 ENOPYRANOSYL)URACIL; 1,2,3,4 TETRA O ACETYL ALPHA DEXTRO LYXOPYRANOSE; EXOMETHYLENE NUCLEOSIDE; NUCLEOSIDE ANALOG; OXONUCLEOSIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL STRAIN CACO 2; CELL STRAIN MCF 7; CONTROLLED STUDY; COXSACKIE VIRUS B4; CYTOPATHOGENIC EFFECT; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IC 50; LEUKEMIA L 1210; LYMPHOCYTE; MAMMALIAN ORTHOREOVIRUS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SINDBIS VIRUS; VACCINIA VIRUS; VERO CELL; VESICULAR STOMATITIS VIRUS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CACO-2 CELLS; CELL LINE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MICE; NUCLEOSIDES;

EID: 67649386569     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900004     Document Type: Article

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