A general and efficient synthesis of 2-substituted oxazolopyridines

Synlett

Volumn , Issue 7, 2009, Pages 1172-1174

  Xu, Dan ^a   Xu, Xianfang ^b   Liu, Zongliang ^a   Sun, Li Ping ^a   You, Qidong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Copper catalyzed cyclization; Heterocycles; Oxazolo 4,5 b pyridines; Oxazolo 5,4 b pyridines; Synthesis

Indexed keywords

COPPER; OXAZOLO[4,5 B]PYRIDINE DERIVATIVE; OXAZOLO[5,4 B]PYRIDINE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CYCLIZATION; REACTION ANALYSIS; REACTION OPTIMIZATION; SYNTHESIS;

EID: 67649385990     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0028-1088149     Document Type: Article

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26. 4 and concentrated in vacuo to give the crude product, which was further purified by flash chromatography over silica gel column with PE-EtOAc (5:1) to give the pure product 3a.
27. 2O: C, 46.45; H, 2.70, N, 8.33. Found: C, 46.53; H, 2.75; N, 8.40.