Activation of phospholipase A2 is involved in indomethacin-induced damage in Caco-2 cells

Toxicology in Vitro

Volumn 23, Issue 5, 2009, Pages 887-896

  Sivalingam, Nageswaran ^a   Basivireddy, Jayasree ^a   Pulimood, Anna B ^a   Balasubramanian, K A ^a   Jacob, Molly ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Anti inflammatory agents, non steroidal; Caco 2 cells; Cell death; Indomethacin; Methyl arachidonyl fluorophosphonate; Phospholipase A2, cytosolic

Indexed keywords

ARACHIDONIC ACID; ENZYME INHIBITOR; INDOMETACIN; LYSOPHOSPHOLIPID; MEMBRANE LIPID; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A2; PHOSPHOLIPID; PHOSPHONIC ACID DERIVATIVE; ARACHIDONIC ACID DERIVATIVE; CYTOSOLIC PHOSPHOLIPASE A2; METHYL ARACHIDONYLFLUOROPHOSPHONATE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL STRAIN CACO 2; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENTEROPATHY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTESTINE CELL; LIPID DEGRADATION; OXIDATIVE STRESS; PATHOGENESIS; CELL SURVIVAL; DRUG EFFECT; METABOLISM;

RATTUS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CACO-2 CELLS; CELL SURVIVAL; ENZYME INHIBITORS; HUMANS; INDOMETHACIN; LYSOPHOSPHOLIPIDS; OXIDATIVE STRESS; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHONIC ACIDS;

EID: 67649381625     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.05.008     Document Type: Article

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