Hypertonic saline attenuates TNF-α-induced NF-κB activation in pulmonary epithelial cells

Shock

Volumn 31, Issue 5, 2009, Pages 466-472

  Nydam, Trevor L ^a   Moore, Ernest E ^a,b   McIntyre Jr , Robert C ^a   Wright, Franklin L ^a   Gamboni Robertson, Fabia ^a   Eckels, Phillip C ^a,b   Banerjee, Anirban ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

Author keywords

Acute lung injury; I B ; ICAM 1; p38 MAPK; VEGF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ACUTE LUNG INJURY; ARTICLE; ATTENUATION; CELL ADHESION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS CELL; PHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; LUNG; METABOLISM; PROTEIN TRANSPORT; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; LUNG; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN TRANSPORT; SALINE SOLUTION, HYPERTONIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649344703     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31818ec47d     Document Type: Article

References (40)

1. Mattox KL, Maningas PA, Moore EE, Mateer JR, Marx JA, Aprahamian C, Burch JM, Pepe PE: Prehospital hypertonic saline/dextran infusion for post-traumatic hypotension. The U.S.A. Multicenter Trial. Ann Surg 213:482-491, 1991.
2. Junger WG, Coimbra R, Liu FC, Herdon-Remelius C, Junger W, Junger H, Loomis W, Hoyt DB, Altman A: Hypertonic saline resuscitation: a tool to modulate immune function in trauma patients? Shock 8:235-241, 1997.
3. Rizoli SB, Rhind SG, Shek PN, Inaba K, Filips D, Tien H, Brenneman F, Rotstein O: The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial. Ann Surg 243:47-57, 2006.
4. Abraham E, Carmody A, Shenkar R, Arcaroli J: Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 279:L1137-L1145, 2000.
5. Burns AR, Smith CW, Walker DC: Unique structural features that influence neutrophil emigration into the lung. Physiol Rev 83:309-336, 2003.
6. Barsness KA, Arcaroli J, Harken AH, Abraham E, Banerjee A, Reznikov L, McIntyre RC: Hemorrhage-induced acute lung injury is TLR-4 dependent. Am J Physiol Regul Integr Comp Physiol 287:R592-R599, 2004.
7. Pascual JL, Ferri LE, Seely AJ, Campisi G, Chaudhury P, Giannias B, Evans DC, Razek T, Michel RP, Christou NV: Hypertonic saline resuscitation of hemorrhagic shock diminishes neutrophil rolling and adherence to endothelium and reduces in vivo vascular leakage. Ann Surg 236:634-642, 2002.
8. Rizoli SB, Kapus A, Fan J, Li YH, Marshall JC, Rotstein OD: Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock. J Immunol 161:6288-6296, 1998.
9. Angle N, Hoyt DB, Coimbra R, Liu F, Herdon-Remelius C, Loomis W, Junger WG: Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock. Shock 9:164-170, 1998.
10. Angle N, Cabello-Passini R, Hoyt DB, Loomis WH, Shreve A, Namiki S, Junger WG: Hypertonic saline infusion: can it regulate human neutrophil function? Shock 14:503-508, 2000.
11. Ciesla DJ, Moore EE, Gonzalez RJ, Biffl WL, Silliman CC: Hypertonic saline inhibits neutrophil (PMN) priming via attenuation of p38 MAPK signaling. Shock 14:265-269; discussion 269-270, 2000.
12. Junger WG, Hoyt DB, Davis RE, Herdon-Remelius C, Namiki S, Junger H, Loomis W, Altman A: Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38. J Clin Invest 101:2768-2779, 1998.
13. Orlic T, Loomis WH, Shreve A, Namiki S, Junger WG: Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and - independent mechanisms. Am J Physiol Cell Physiol 282:C1261-C1269, 2002.
14. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV: Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. J Immunol 168: 1389-1396, 2002.
15. Shukla A, Hashiguchi N, Chen Y, Coimbra R, Hoyt DB, Junger WG: Osmotic regulation of cell function and possible clinical applications. Shock 21: 391-400, 2004.
16. Ayala A, Perrin MM, Meldrum DR, Ertel W, Chaudry IH: Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin. Cytokine 2:170-174, 1990.
17. Mukhopadhyay S, Hoidal JR, Mukherjee TK: Role of TNFalpha in pulmonary pathophysiology. Respir Res 7:125, 2006.
18. Atsuta J, Sterbinsky SA, Plitt J, Schwiebert LM, Bochner BS, Schleimer RP: Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1. Am J Respir Cell Mol Biol 17:571-582, 1997.
19. Song Y, Ao L, Raeburn CD, Calkins CM, Abraham E, Harken AH, Meng X: A low level of TNF-alpha mediates hemorrhage-induced acute lung injury via p55 TNF receptor. Am J Physiol Lung Cell Mol Physiol 281:L677-L684, 2001.
20. Thorley AJ, Ford PA, Giembycz MA, Goldstraw P, Young A, Tetley TD: Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages. J Immunol 178:463-473, 2007.
21. Hacker H, Karin M: Regulation and function of IKK and IKK-related kinases. Sci STKE 2006:re13, 2006.
22. Ciesla DJ, Moore EE, Biffl WL, Gonzalez RJ, Silliman CC: Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge. Surgery 129:567-575, 2001.
23. Fehrenbach A, Pufe T, Wittwer T, Nagib R, Dreyer N, Pech T, Petersen W, Fehrenbach H, Wahlers T, Richter J: Reduced vascular endothelial growth factor correlates with alveolar epithelial damage after experimental ischemia and reperfusion. J Heart Lung Transplant 22:967-978, 2003.
24. Mura M, Han B, Andrade CF, Seth R, Hwang D, Waddell TK, Keshavjee S, Liu M: The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival. Crit Care 10: R130, 2006.
25. Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med 342:1334-1349, 2000.
26. Islam A, Adamik B, Hawari F I, Ma G, Rouhani FN, Zhang J, Levine SJ: Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex. J Biol Chem 281:6860-6873, 2006.
27. Sheikh-Hamad D, Gustin MC: MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals. Am J Physiol Renal Physiol 287:F1102-F1110, 2004.
28. Wajant H, Pfizenmaier K, Scheurich P: Tumor necrosis factor signaling. Cell Death Differ 10:45-65, 2003.
29. Holden NS, Catley MC, Cambridge LM, Barnes PJ, Newton R: ICAM-1 expression is highly NF-kappaB-dependent in A549 cells. No role for ERK and p38 MAPK. Eur J Biochem 271:785-791, 2004.
30. Skerrett SJ, Liggitt HD, Hajjar AM, Ernst RK, Miller SI, Wilson CB: Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin. Am J Physiol Lung Cell Mol Physiol 287:L143-L152, 2004.
31. Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS: Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation. J Immunol 170: 1091-1098, 2003.
32. Poynter ME, Irvin CG, Janssen-Heininger YM: A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation. J Immunol 170:6257-6265, 2003.
33. Staudenmayer KL, Maier RV, Jelacic S, Bulger EM: Hypertonic saline modulates innate immunity in a model of systemic inflammation. Shock 23: 459-463, 2005.
34. Simon RH, DeHart PD, Todd RF 3rd: Neutrophil-induced injury of rat pulmonary alveolar epithelial cells. J Clin Invest 78:1375-1386, 1986.
35. Beck-Schimmer B, Madjdpour C, Kneller S, Ziegler U, Pasch T, Wuthrich RP, Ward PA, Schimmer RC: Role of alveolar epithelial ICAM-1 in lipopolysaccharide-induced lung inflammation. Eur Respir J 19:1142-1150, 2002.
36. Beck-Schimmer B, Schimmer RC, Schmal H, Flory CM, Friedl HP, Pasch T, Ward P: Characterization of rat lung ICAM-1. Inflamm Res 47:308-315, 1998.
37. Schmal H, Czermak BJ, Lentsch AB, Bless NM, Beck-Schimmer B, Friedl HP, Ward PA: Soluble ICAM-1 activates lung macrophages and enhances lung injury. J Immunol 161:3685-3693, 1998.
38. Powers KA, Woo J, Khadaroo RG, Papia G, Kapus A, Rotstein OD: Hypertonic resuscitation of hemorrhagic shock upregulates the anti-inflammatory response by alveolar macrophages. Surgery 134:312-318, 2003.
39. Donaldson SH, Bennett WD, Zeman KL, Knowles MR, Tarran R, Boucher RC: Mucus clearance and lung function in cystic fibrosis with hypertonic saline. N Engl J Med 354:241-250, 2006.
40. Elkins MR, Robinson M, Rose BR, Harbour C, Moriarty CP, Marks GB, Belousova EG, Xuan W, Bye PT: A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. N Engl J Med 354:229-240, 2006.