5,10-Methylenetetrahydrofolate reductase (MTHFR) low activity genotypes reduce the risk of relapse-related acute lymphoblastic leukemia (ALL)

Leukemia Research

Volumn 33, Issue 10, 2009, Pages 1344-1348

  Karas Kuzelicki, Natasa ^a   Milek, Miha ^a   Jazbec, Janez ^b   Mlinaric Rascan, Irena ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY CHILDREN S HOSPITAL   (Slovenia)

Author keywords

Carcinogenesis; Leukemia; MTHFR; Relapse

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; METHOTREXATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CONTROLLED STUDY; DRUG MEGADOSE; ENZYME ACTIVITY; FEMALE; FOLATE METABOLISM; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; LEUKEMIA RELAPSE; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; PREGNANCY; PRIORITY JOURNAL; RECURRENCE RISK; RISK REDUCTION; SLOVENIA; VITAMIN SUPPLEMENTATION;

CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; DNA, NEOPLASM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NAD+); MUTATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; REFERENCE VALUES; RETROSPECTIVE STUDIES; RISK FACTORS; SLOVENIA;

EID: 67649331653     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.12.011     Document Type: Article

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