Transplantation

Handbook of Clinical Neurology

Volumn 84, Issue , 2007, Pages 279-290

  Freed, Curt R ^a   Michael Zawada, W ^a   Leehey, Maureen ^a   Zhou, Wenbo ^a   Breeze, Robert E ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 67649329426     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0072-9752(07)84044-9     Document Type: Chapter

References (84)

1. Alexander G.E., and DeLong M.R. Microstimulation of the primate neostriatum. II. Somatotopic organization of striatal microexcitable zones and their relation to neuronal response properties. J Neurophysiol 53 (1985) 1417-1430
2. Annett L.E., Martel F.L., Rogers D.C., et al. Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 125 (1994) 228-246
3. Annett L.E., Torres E.M., Ridley R.M., et al. A comparison of the behavioural effects of embryonic nigral grafts in the caudate nucleus and in the putamen of marmosets with unilateral 6-OHDA lesions. Exp Brain Res 103 (1995) 355-371
4. Annett L.E., Torres E.M., Clarke D.J., et al. Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age. Cell Transplant 6 (1997) 557-569
5. Bakay R., Fiandaca M.S., Barrow D.L., et al. Preliminary report of the use of fetal tissue transplantation to correct MPTP-induced Parkinson-like symptoms in primates. Appl Neurophysiol 48 (1985) 358-361
6. Bankiewicz K.S., Oldfield E.H., Chiueh C.C., et al. Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life Sci 39 (1986) 7-16
7. Bernheimer H., Birkmayer W., Hornykiewicz O., et al. Brain dopamine and the syndromes of Parkinson and Huntington's: clinical, morphological and neurochemical correlations. J Neurol Sci 20 (1973) 415-455
8. Bjorklund A., and Steveni U. Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants. Brain Res 177 (1979) 555-560
9. Bjorklund A., Dunnett S., Brundin P., et al. Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol 2 (2003) 437-445
10. Bjorklund L.M., Sanchez-Pernaute R., Chung S., et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 99 (2002) 2344-2349
11. Brundin P., Nilsson O.G., Strecker R.E., et al. Behavioral effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease. Exp Brain Res 65 (1986) 235-240
12. Brundin P., Pogarell O., Hagell P., et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 123 (2000) 1380-1390
13. Burns R.S., Chiueh C.C., Markey S.P., et al. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 80 (1983) 4546-4550
14. Buytaert-Hoefen K.A., Alvarez E., and Freed C.R. Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF. Stem Cells 22 (2004) 669-674
15. Chung S., Shin B.S., Hedlund E., et al. Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation. J Neurochem 97 (2006) 1467-1480
16. Clarkson E.D., and Freed C.R. Minireview: development of fetal neural transplantation as a treatment for Parkinson's disease. Life Sci 65 (1999) 2427-2437
17. Clarkson E.D., Zawada W.M., and Freed C.R. GDNF reduces apoptosis in dopaminergic neurons in vitro. Neuroreport 7 (1995) 145-149
18. Clarkson E.D., La Rosa F.C., Edwards-Prasad J., et al. Improvement of neurological deficits in 6-hydroxydopamine-lesioned rats after transplantation with allogeneic simian virus 40 large tumor antigen gene-induced immortalized dopamine cells. Proc Natl Acad Sci USA 95 (1998) 1256-1270
19. Clarkson E.D., Zawada W.M., Adams F.S., et al. Strands of embryonic mesencephalic tissue show greater dopamine neuron survival and better behavioral improvement than cell suspensions after transplantation in parkinsonian rats. Brain Res 806 (1998) 60-68
20. Date I., Imaoka T., Miyoshi Y., et al. Chromaffin cell survival and host dopaminergic fiber recovery in a patient with Parkinson's disease treated by cografts of adrenal medulla and pretransected peripheral nerve. Case report. J Neurosurg 84 (1996) 685-689
21. Davis G.C., Williams A.C., Markey S.P., et al. Chronic Parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Res 1 (1979) 249-254
22. Deacon T., Schumacher J., Dinsmore J., et al. Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease. Nat Med 3 (1997) 350-353
23. Dunnett S.B., Hernandez T.O., Summerfield A., et al. Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissues. Exp Brain Res 71 (1988) 411-424
24. Emerich D.F., Winn S.R., Christenson L., et al. A novel approach to neural transplantation in Parkinson's disease: use of polymer-encapsulated cell therapy. Neurosci Biobehav Rev 16 (1992) 437-447
25. Freed C.R., Richards J.B., Sabol K.E., et al. Fetal substantia nigra transplants lead to dopamine cell replacement and behavioral improvement in Bonnet monkeys with MPTP induced Parkinsonism. In: Beart P.M., Woodruff G., and Jackson D.M. (Eds). Pharmacology and Functional Regulation of Dopaminergic Neurons (1988), Macmillan Press, London 353-360
26. Freed C.R., Breeze R.E., Rosenberg N.L., et al. Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year. Arch Neurol 47 (1990) 505-512
27. Freed C.R., Breeze R.E., Rosenberg N.L., et al. Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease. N Engl J Med 327 (1992) 1549-1555
28. Freed C.R., Breeze R.E., Schneck S.A., et al. Fetal neural transplantation for Parkinson's disease. In: Rich R.R. (Ed). Clinical Immunology; Principles and Practice (1995), Mosby-Year Book, St. Louis 1677-1687
29. Freed C.R., Greene P.E., Breeze R.E., et al. Transplantation of embryonic dnpamine neurons for severe Parkinson's disease. N Engl J Med 344 (2001) 710-719
30. Freed C.R., Breeze R.E., Fahn S., et al. Preoperative response to levodopa is the best predictor of transplant outcome. Ann Neurol 55 (2004) 896
31. Freed C.R., Zawada M., DeMasters B.K., et al. Human embryonic dopamine neurons transplanted into Parkinson patients survive and improve motor function for at least 10 years without immunosuppression. Program No. 329.6. 2005 Abstract Viewer/Itinerary Planner (2005), Society for Neuroscience, Washington, DC [Online]
32. Freed W.J. Functional brain tissue transplantation: reversal of lesion-induced rotation by intraventricular substantia nigra and adrenal medulla grafts, with a note on intracranial retinal grafts. Biol Psychiatry 18 (1983) 1205-1267
33. Freed W.J., Morihisa J.M., Spoor E., et al. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour. Nature 292 (1981) 351-352
34. Freeman T.B., Olanow C.W., Hauser B.A., et al. Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease. Ann Neurol 38 (1995) 379-388
35. Freeman T.B., Sanberg P.R., Nauert C.M., et al. The influence of donor age on the survival of solid and suspension inrraparenchymal human embryonic nigral cells. Cell Transplant 4 (1995) 141-154
36. Goetz C.G., Stebbins III G.T., Klawans H.L., et al. United Parkinson Foundation Neurotransplantation Registry on adrenal medullary transplants: presurgical, and 1- and 2-year follow-up. Neurology 41 (1991) 1719-1722
37. Gordon P.H., Yu Q., Qualls C., et al. Reaction time and movement time after embryonic cell implantation in Parkinson disease. Arch Neurol 61 (2004) 858-861
38. Hagell P., Piccini P., Bjorklund A., et al. Dyskinesias following neural transplantation in Parkinson's disease. Nat Neurosci 5 (2002) 627-628
39. Hikosaka O., Sakamoto M., and Usui S. Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements. J Neurophysiol 61 (1989) 780-798
40. Hikosaka O., Sakamoto M., and Usui S. Functional properties of monkey caudate neurons. III. Activities related to expectation of target and reward. J Neurophysiol 61 (1989) 814-832
41. Hudson J.L., Bickford P., Johansson M., et al. Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. J Neurosci 14 (1994) 283-290
42. Hurtig H., Joyce J., Sladek Jr. J.R., et al. Postmortem analysis of adrenal-medulla-to-caudate autograft in a patient with Parkinson's disease. Ann Neurol 25 (1989) 607-614
43. Kawasaki H., Mizuseki K., Nishikawa S., et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28 (2000) 31-40
44. Kim J.H., Auerbach J.M., Rodriguez-Gomez J.A., et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature 418 (2002) 50-56
45. Kish S.J., Shannak K., and Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. N Engl J Med 318 (1988) 876-880
46. Kopyov O.V., Jacques O., Lieberman A., et al. Clinical study of fetal mesencephalic intracerebral transplants for the treatment of Parkinson's disease. Cell Transplant 5 (1996) 327-337
47. Kopyov O.V., Jacques D.S., Lieberman A., et al. Outcome following intrastriatal fetal mesencephalic grafts for Parkinson's patients is directly related to the volume of grafted tissue. Exp Neurol 146 (1997) 536-545
48. Kordower J.H., Freeman T.B., Snow B.J., et al. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med 332 (1995) 1118-1124
49. Kori A., Miyashita N., Kato M., et al. Eye movements in monkeys with local dopamine depletion in the caudate nucleus. II. Deficits in voluntary saccades. J Neurosci 15 (1995) 928-941
50. Lang A., and Obeso O. Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough. Lancet Neurology 3 (2004) 309-316
51. Langston J.W., Ballard P., Tetrud J.W., et al. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219 (1983) 979-980
52. Langston J.W., Widner H., Goetz C.G., et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 7 (1992) 2-13
53. Lee S.H., Lumelsky N., Studer L., et al. Efficient generation of mid-brain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 18 (2000) 675-679
54. Lindvall O., Rehncrona S., Brundin P., et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. Arch Neurol 46 (1989) 615-631
55. Lindvall O., Brundin P., Widner H., et al. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 247 (1990) 574-577
56. Ma Y., Feigin A., Dhawan V., et al. Dyskinesia after fetal cell transplantation for parkinsonism: a PET study. Ann Neurol 52 (2002) 628-634
57. Madrazo I., Drucker-Colin T., Daiz V., et al. Open micro-surgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson's disease. N Eng J Med 316 (1987) 831-833
58. Mahalik T.J., Finger T.E., Stromberg I., et al. Subsranria nigra transplants into denervated srriatum of the rat ultrastrucrure of graft and host interconnections. J Comp Neurol 240 (1985) 60-70
59. Nakamura T., Dhawan V., Chaly T., et al. Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease. Ann Neurol 50 (2001) 181-187
60. Olanow C.W., Goetz C.G., Kordower J.H., et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 54 (2003) 403-414
61. Pakkenberg B., Moller A., Cundersen H.J., et al. The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with unbi-based stereological method. J Neurol Neurosurg Psychiatry 54 (1991) 30-33
62. Palzaban P., Deacon T.W., Burns L.H., et al. A novel mode of immunoprotection of neural xenotransplants: masking of donor major histocompatibility complex class I enhances transplant survival in the central nervous system. Neuroscience 65 (1995) 983-996
63. Perlow M.J., Freed W.J., Hoffer B.J., et al. Brain grafts reduce motor abnormalities produced by destruction of nigrosttiatal dopamine system. Science 204 (1979) 555-560
64. Perrier A.L., Tabar V., Barberi T., et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci USA 101 (2004) 12543-12548
65. Peschanski M., Defer C., N'Guyen J.P., et al. Bilateral motor improvement and lateralization of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon. Brain 117 (1994) 487-499
66. Redmond D.E., Sladek Jr. J.R., Roth R.H., et al. Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine. Lancet 8490 (1986) 1125-1127
67. Schierle G.S., Hansson O., Leist M., et al. Caspase inhibition reduces apoptosis and increases survival of nigral transplants. Nat Med 5 (1999) 97-100
68. Schmidt R.H., Ingvar M., Lindvall O., et al. Functional activity of substantia nigra grafts reinnervating the striatum: neurotransmitter metabolism and (14C)-2-deoxy-D-glucose autoradiography. J Neurochem 38 (1982) 737-748
69. Shim J.W., Koh H.C., Chang M.Y., et al. Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL. J Neurosci 24 (2004) 843-852
70. Spencer D.D., Robbins R.J., Naftojin F., et al. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. N Engl J Med 327 (1992) 1541-1548
71. Stover N.P., Bakay R.A., Subramanian T., et al. Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinson disease. Arch Neurol 62 (2005) 1833-1837
72. Stromberg I., Herrera-Marschitz M., Ungerstedt U., et al. Chronic implants of chromaffin tissue into the dopamine-denervated striatum. Effects of NGF on graft survival, fiber growth and rotational behavior. Exp Brain Res 60 (1985) 335-349
73. Stromberg I., Bygdeman M., Goldstein M., et al. Human fetal substantia nigra grafted to the dopamine-denervated striatum of immunosuppressed rats: evidence for functional reinnervation. Neurosci Lett 71 (1986) 271-276
74. Takagi Y., Takahashi J., Saiki H., et al. Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest 115 (2005) 102-109
75. Takayama H., Ray J., Raymon H.K., et al. Basic fibroblasts growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nat Med 1 (1995) 53-58
76. Trott C.T., Fahn S., Greene P., et al. Cognition following bilateral implants of embryonic dopamine neurons in PD: a double blind study. Neurology 60 (2003) 1938-1943
77. Ungerstedt U., and Arbuthoott C.W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Res 24 (1970) 485-493
78. Watts R.L., Subramanian T., Freeman A., et al. Effect of stereotaxic intrastriatal cografts of autologous adrenal medulla and peripheral nerve in Parkinson's disease: two-year follow-up study. Exp Neurol 147 (1997) 510-517
79. Widner H., Tetrud J., Rehncrona S., et al. Bilateral fetal mesencephalic grafting in two patients with Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). N Engl J Med 327 (1992) 1556-1563
80. Wuerthele S.M., Freed W.J., Olson L., et al. Effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat. Exp Brain Res 44 (1981) 1-10
81. Yan Y., Yang D., Zarnowska E.D., et al. Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 23 (2005) 781-790
82. Zawada W.M., Kirschman D.L., Cohen J.J., et al. Growth factors rescue embryonic dopamine neurons from programmed cell death. Exp Neurol 140 (1996) 60-67
83. Zawada W.M., Cibelli J.B., Choi P.K., et al. Somatic cell cloned transgenic bovine neurons for transplantation in parkinsonian rats. Nat Med 4 (1998) 569-574
84. Zawada W.M., Zastrow D.J., Clarkson E.D., et al. Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats. Brain Res 786 (1998) 96-103