Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease

Annals of Neurology

Volumn 50, Issue 2, 2001, Pages 181-187

  Nakamura, Toshitaka ^a   Dhawan, Vijay ^a   Chaly, Thomas ^b   Fukuda, Masafumi ^c   Yilong, Ma ^d   Breeze, Robert ^a   Greene, Paul ^a   Fahn, Stanley ^a   Freed, Curt ^c   Eidelberg, David ^a  

^a North Shore Long Island Jewish Research Institute ^*  (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Columbia College of Physicians and Surgeons ^*  (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN SCINTISCANNING; CELL TRANSPLANTATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO CELL; FEMALE; GRAFT SURVIVAL; HUMAN; IMAGE ANALYSIS; MALE; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADULT; AGE FACTORS; AGED; DIHYDROXYPHENYLALANINE; DOUBLE-BLIND METHOD; HUMANS; MIDDLE AGED; PARKINSON DISEASE; PUTAMEN; SUBSTANTIA NIGRA; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0034909937     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.1075     Document Type: Article

References (30)

1. Transplantation of embryonic dopamine neurons for severe Parkinson's disease
2. 18F]fluoro-dopa and positron emission tomography: Error analysis and application to normal subjects
3. Combined FDOPA and 3OMFD PET studies in Parkinson's disease
4. 18F]fluorodopa studies correlate with dopamine cell counts and levels
5. Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices
6. 18F]fluorodopa positron emission tomographic studies
7. Input functions for 6-[fluorine-18]fluorodopa quantitation in parkinsonism: Comparative studies and clinical correlations
8. Clinical significance of striatal DOPA decarboxylase activity in Parkinson's disease
9. Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET
10. The role of positron emission tomography in the assessment of human neurotransplantation
11. Survival of implanted fetal dopamine cells and neurologic improvement 12-46 months after transplantation for Parkinson's disease
12. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
13. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
14. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
15. 18F]fluorodopa uptake in five grafted parkinsonian patients
16. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
17. Unified Parkinson's disease rating scale
18. Performance characteristics of a whole-body PET scanner
19. Reproducibility of repeated mountings of a noninvasive CT/MRI stereoadapter
20. 18F]fluoro-L-dopa for human studies with PET
21. 18F]6-L-fluorodopa studies in two patients with putaminal implants
22. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
23. Levodopa infusion reduces the expression of a Parkinson's disease metabolic brain network: An FDG PET study
24. Diminished viability, growth, and behavioral efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: An argument for neurotrophic supplementation
25. Assessment of fetal tissue transplantation in Parkinson's disease: Does PET play a role?
26. The metabolic topography of normal aging
27. Positron emission tomography suggests that the rate of progression of idiopathic parkinsonism is slow
28. Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism
29. 18F]dopa metabolism in the striatum in Parkinson's disease