Identifying drug-induced repolarization abnormalities from distinct ECG patterns in congenital long QT syndrome: A study of sotalol effects on T-wave morphology

Drug Safety

Volumn 32, Issue 7, 2009, Pages 599-611

  Graff, Claus ^a   Andersen, Mads P ^a   Xue, Joel Q ^b   Hardahl, Thomas B ^a   Kanters, Jørgen K ^c,d,e   Toft, Egon ^a,e   Christiansen, Michael ^f   Jensen, Henrik K ^g   Struijk, Johannes J ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b GE HEALTHCARE   (United States)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e AALBORG UNIVERSITY HOSPITAL   (Denmark)

^f STATENS SERUM INSTITUT   (Denmark)

^g AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

SOTALOL;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ECG ABNORMALITY; FEMALE; HEART RATE; HEART REPOLARIZATION; HUMAN; LONG QT SYNDROME; MALE; MAXIMUM PLASMA CONCENTRATION; POTASSIUM CURRENT; PRIORITY JOURNAL; QT PROLONGATION; QUANTITATIVE DIAGNOSIS; SIDE EFFECT; SINGLE DRUG DOSE; T WAVE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADOLESCENT; ADULT; ANTI-ARRHYTHMIA AGENTS; AREA UNDER CURVE; DIAGNOSIS, COMPUTER-ASSISTED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; HUMANS; LONG QT SYNDROME; MALE; MIDDLE AGED; SINGLE-BLIND METHOD; SOTALOL; YOUNG ADULT;

EID: 67649262232     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.2165/00002018-200932070-00006     Document Type: Article

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