Human gingival fibroblasts release high-mobility group box-1 protein through active and passive pathways

Oral Microbiology and Immunology

Volumn 24, Issue 4, 2009, Pages 292-298

  Feghali, K ^a   Iwasaki, K ^a   Tanaka, K ^a   Komaki, M ^a   MacHigashira, M ^b   Ishikawa, I ^c   Izumi, Y ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; High mobility group box 1; Human gingival fibroblasts; Lipopolysaccharides; Necrosis

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; LIPOPOLYSACCHARIDE;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; APOPTOSIS; ARTICLE; BACTERIUM DETECTION; CELL DEATH; CELL STIMULATION; CELL STRESS; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; FIBROBLAST; GINGIVA; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; NECROSIS; PATHOGENESIS; PORPHYROMONAS GINGIVALIS; PROTEIN SECRETION; REACTION TIME; SUPERNATANT; TISSUE CULTURE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; CELL DEATH; FIBROBLASTS; GINGIVA; HMGB1 PROTEIN; HUMANS; LIPOPOLYSACCHARIDES; PORPHYROMONAS GINGIVALIS;

EID: 67649230571     PISSN: 09020055     EISSN: 1399302X     Source Type: Journal    
DOI: 10.1111/j.1399-302X.2009.00508.x     Document Type: Article

References (37)

1. Andersson U, Erlandsson-Harris H. HMGB1 is a potent trigger of arthritis. J Intern Med 2004 : 255 : 344 350. (Pubitemid 38315275)
2. Bell CW, Jiang W, Reich CF 3rd., Pisetsky DS. The extracellular release of HMGB1 during apoptotic cell death. Am J Physiol Cell Physiol 2006 : 291 : C1318 C1325.
3. Bianchi ME, Manfredi AA. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev 2007 : 220 : 35 46. (Pubitemid 350045574)
4. Bodet C, Andrian E, Tanabe S, Grenier D. Actinobacillus actinomycetemcomitans lipopolysaccharide regulates matrix metalloproteinase, tissue inhibitors of matrix metalloproteinase, and plasminogen activator production by human gingival fibroblasts: a potential role in connective tissue destruction. J Cell Physiol 2007 : 212 : 189 194. (Pubitemid 46867601)
5. Bonaldi T, Talamo F, Scaffidi P et al. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003 : 22 : 5551 5560. (Pubitemid 37279964)
6. Bustin M, Hopkins RB, Isenberg I. Immunological relatedness of high mobility group chromosomal proteins from calf thymus. J Biol Chem 1978 : 253 : 1694 1699. (Pubitemid 8312351)
7. Charoonpatrapong K, Shah R, Robling AG et al. HMGB1 expression and release by bone cells. J Cell Physiol 2006 : 207 : 480 490.
8. Dongari-Bagtzoglou AI, Ebersole JL. Production of inflammatory mediators and cytokines by human gingival fibroblasts following bacterial challenge. J Periodontal Res 1996 : 31 : 90 98.
9. Erlandsson Harris H, Andersson U. Mini-review: the nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol 2004 : 34 : 1503 1512. (Pubitemid 39256031)
10. Gardella S, Andrei C, Ferrera D et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep 2002 : 3 : 995 1001. (Pubitemid 35256475)
11. Germani A, Limana F, Capogrossi MC. Pivotal advances: high-mobility group box 1 protein - a cytokine with a role in cardiac repair. J Leukoc Biol 2007 : 81 : 41 45. (Pubitemid 46021250)
12. Hori O, Brett J, Slattery T et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 1995 : 270 : 25752 25761.
13. Huttunen HJ, Kuja-Panula J, Rauvala H. Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation. J Biol Chem 2002 : 277 : 38635 38646. (Pubitemid 35154724)
14. Ivanov S, Dragoi AM, Wang X et al. A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 2007 : 110 : 1970 1981. (Pubitemid 47443911)
15. Jiang W, Li J, Gallowitsch-Puerta M, Tracey KJ, Pisetsky DS. The effects of CpG DNA on HMGB1 release by murine macrophage cell lines. J Leukoc Biol 2005 : 78 : 930 936. (Pubitemid 41384409)
16. Katz J, Caudle RM, Bhattacharyya I, Stewart CM, Cohen DM. Receptor for advanced glycation end product (RAGE) upregulation in human gingival fibroblasts incubated with nornicotine. J Periodontol 2005 : 76 : 1171 1174. (Pubitemid 41065408)
17. Kesavalu L, Chandrasekar B, Ebersole JL. In vivo induction of proinflammatory cytokines in mouse tissue by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol 2002 : 17 : 177 180. (Pubitemid 34580755)
18. Kurita-Ochiai T, Seto S, Suzuki N et al. Butyric acid induces apoptosis in inflamed fibroblasts. J Dent Res 2008 : 87 : 51 55.
19. Li CH, Amar S. Inhibition of SFRP1 reduces severity of periodontitis. J Dent Res 2007 : 86 : 873 877.
20. Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005 : 5 : 331 342. (Pubitemid 40516158)
21. Moore WE, Moore LV. The bacteria of periodontal diseases. Periodontol 2000 1994 : 5 : 66 77.
22. Morimoto Y, Kawahara KI, Tancharoen S et al. Tumor necrosis factor-alpha stimulates gingival epithelial cells to release high mobility-group box 1. J Periodontal Res 2008 : 43 : 76 83.
23. Park JS, Svetkauskaite D, He Q et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004 : 279 : 7370 7377. (Pubitemid 38294612)
24. Pisetsky DS, Jiang W. Role of Toll-like receptors in HMGB1 release from macrophages. Ann N Y Acad Sci 2007 : 1109 : 58 65. (Pubitemid 47511345)
25. Rovere-Querini P, Capobianco A, Scaffidi P et al. HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep 2004 : 5 : 825 830. (Pubitemid 39199174)
26. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002 : 418 : 191 195. (Pubitemid 34773774)
27. Sha Y, Zmijewski J, Xu Z, Abraham E. HMGB1 develops enhanced proinflammatory activity by binding to cytokines. J Immunol 2008 : 180 : 2531 2537.
28. Sheets SM, Potempa J, Travis J, Casiano CA, Fletcher HM. Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells. Infect Immun 2005 : 73 : 1543 1552. (Pubitemid 40470740)
29. Tian J, Avalos AM, Mao SY et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 2007 : 8 : 487 496. (Pubitemid 46605917)
30. van Beijnum JR, Buurman WA, Griffioen AW. Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis 2008 : 11 : 91 99.
31. Wahamaa H, Vallerskog T, Qin S et al. HMGB1-secreting capacity of multiple cell lineages revealed by a novel HMGB1 ELISPOT assay. J Leukoc Biol 2007 : 81 : 129 136. (Pubitemid 46021261)
32. Wang H, Bloom O, Zhang M et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999 : 285 : 248 251. (Pubitemid 29329996)
33. Wassenaar A, Snijders A, Abraham-Inpijn L, Kapsenberg ML, Kievits F. Antigen-presenting properties of gingival fibroblasts in chronic adult periodontitis. Clin Exp Immunol 1997 : 110 : 277 284. (Pubitemid 27469602)
34. Youn JH, Oh YJ, Kim ES, Choi JE, Shin JS. High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes. J Immunol 2008 : 180 : 5067 5074.
35. Youn JH, Shin JS. Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion. J Immunol 2006 : 177 : 7889 7897.
36. Zeh HJ 3rd., Lotze MT. Addicted to death: invasive cancer and the immune response to unscheduled cell death. J Immunother 2005 : 28 : 1 9. (Pubitemid 40075932)
37. Zeldich E, Koren R, Dard M, Nemcovsky C, Weinreb M. Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation. J Cell Physiol 2007 : 213 : 750 758. (Pubitemid 350058268)