Production of inflammatory mediators and cytokines by human gingival fibroblasts following bacterial challenge

Journal of Periodontal Research

Volumn 31, Issue 2, 1996, Pages 90-98

  Dongari Bagtzoglou, A I ^a   Ebersole, J L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

A. actinomycetemcomitans; C. rectus; Cytokines; Fibroblasts

Indexed keywords

AUTACOID; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; PROSTAGLANDIN E2;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ARTICLE; BIOSYNTHESIS; CAMPYLOBACTER; CELL CULTURE; CLASSIFICATION; FIBROBLAST; GINGIVA; HUMAN; IMMUNIZATION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PERIODONTITIS; PERIODONTIUM; PHYSIOLOGY; SEROTYPING;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; CAMPYLOBACTER; CELLS, CULTURED; CYTOKINES; DINOPROSTONE; FIBROBLASTS; GINGIVA; HUMANS; IMMUNIZATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; PERIODONTITIS; PERIODONTIUM; SEROTYPING;

EID: 0030088140     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.1996.tb00469.x     Document Type: Article

References (54)

1. Haffajee AD, Socransky SS, Ebersole JL, Smith DJ. Clinical, microbiological and immunological features associated with the treatment of active periodontitis lesions. J Clin Periodont 1984; 11: 600-618.
2. Dzink JL, Tanner ACR, Haffajee AD, Socransky SS. Gram-negative species associated with active destructive periodontal lesions. J Clin Periodont 1988; 12: 648-659.
3. Tsai CC, Shenker BJ, DiRienzo JM, Malamud D, Taichman NS. Extraction and isolation of a leukotoxin from Actinobacillus actinomycetemcomitans. Infect Immun 1984; 43: 700-705.
4. Robertson PB, Lantz M, Marucha PT, Kornman KS, Trammel CL, Holt SC. Collagenolytic activity associated with Bacteroides species and Actinobacillus actinomycetem-comitans. J Periodont Res 1982; 17: 275-283
5. Birkedal-Hansen H, Caufield PW, Wannenmuehler YM, Pierce R. A sensitive screening assay for epitheliotoxins produced by oral microorganisms. J Dent Res 1982; 61: 192.
6. Stevens RH, Hammond BF Inhibition of fibroblast proliferation by extracts of Capnocytophaga species and Actinobacillus actinomycetemcomitans. J Dent Res 1982; 61: 347.
7. Wyss E. Campylobacter-Wolinella group organisms are the only oral bacteria that form arylsulphatase-active colonies on a synthetic indicator medium. Infect Immun 1989; 57: 1380-1383.
8. Gillespie J, De Nardin E, Radel S, Kuracina J, Smutko J, Zambon JJ. Production of an extracellular toxin by the oral pathogen. Campylobacter rectus. Microbial Pathogenesis 1992; 12: 69-77.
9. Manor A, Lebendiger M. Sniffer A, Tove H. Bacterial invasion of periodontal tissues in advanced periodontitis in humans. J Periodont 1984; 55: 567-573.
10. Sussman HI, Bartels HA, Stahl SS. The potential of microorganisms to invade the lamina propria of human gingival tissues. J Periodont 1969; 40: 210-215.
11. Silverstein LH, Schuster GS, Garnick JJ, Singh B. Bacterial penetration of gingiva in the adult beagle dog with periodontitis. J Periodont 1990; 61: 35-41.
12. 2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells. Infect Immun 1987; 55: 2148-2154.
13. Bartold PM, Haynes DR. Interleukin 6 production by human gingival fibroblasts. J Periodont Res 1991; 26: 339-345.
14. Hanazawa H, Hirosi K, Ohmori Y, Amano S, Kitano S. Bacteroides gingivalis fimbriae stimulate production of thymocyte activating factor by human gingival fibroblasts. Infect Immun 1988; 56: 272-274.
15. Page RC. The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodont Res 1991; 26: 230-242.
16. 2 but not interleukin 1β in patients with adult periodontitis. J Periodont Res 1989; 24: 88-95.
17. Gillespie J, Weintraub ST, Wong G, Holt SC. Chemical and biological characterization of the LPS of the oral pathogen Wolinella recta ATCC 33238. Infect Immun 1988; 56: 2028-2035.
18. Davenport RH, Simpson DM, Hassell TM. Histometric comparison of active and inactive lesions of advanced periodontitis. J Periodontol 1982; 53(5): 285-95.
19. Schou S, Holmstrup P, Kornman KS. Non-human primates used in studies of periodontal disease pathogenesis: a review of the literature. J Periodontol 1993; 64(6): 497-508.
20. Kesavalu L, Holt SC, Crawley RR, Borinski R, Ebersole JL. Virulence of Wolinella recta in a murine abscess model. Infect Immun 1991; 59: 2806-2817.
21. Ebersole JL, Schneider SL, Szekeresova M, Crawley RR, Holt SC. Murine model for virulence characteristics of periodontopathogens. J Dent Res 1989; 68: 286.
22. Richards D, Rutherford RB. The effects of interleukin 1 on collagenolytic activity and prostaglandin E secretion by periodontal ligament and gingival fibroblasts. Arch Oral Biol 1988; 33. 237-243.
23. Van Damme J, Schaafsma R, Fibbe VE, Falkenburg F, Opdenakker G, Billiau A. Simultaneous production of IL-6, IFN-β and colony stimulating activity by fibroblasts after viral and bacterial infection. J Immunol 1989; 19: 163-168.
24. Larsen CG, Oppenheim JJ, Matsushima K. IL-1 or TNF stimulate the production of NAF by normal human fibroblasts and keratinocytes. J Invest Dermatol 1989; 92: 467.
25. 2 and interleukin 1β release from rat periosteal and human gingival fibroblasts in vitro. Oral Microbiol Immunol 1991; 6: 378-380.
26. 2 levels and human periodontal disease. Prostaglandins 1974; 6: 81-85.
27. 2 levels as a predictor or periodontal attachment loss. J Periodont Res 1986; 21: 101-112.
28. Masada MP, Persson R, Kenney JJ, Lee SW. Page RC, Allison AC. Measurement of IL-1α and IL-1β in GCF. Implications for the pathogenesis of periodontal disease J Periodont Res 1990; 25: 156-163.
29. Matsuki Y, Yamamoto T, Hara K. Localization of Interleukin 1 (IL-1) mRNA-expressing macrophages in human inflamed gingiva and IL-1 activity in GCF. J Periodont Res 1993; 28: 35-42.
30. Honing J, Rordorf AC, Siegmund C, Wiedemann W, Erard K. Increased IL-1β concentration in gingival tissues of periodontitis patients. J Periodont Res 1989; 24: 362-367.
31. Geivelis M, Turner DW, Pederson ED, Lamberts BL. Measurements of IL-6 in gingival crevicular fluid from adults with destructive periodontal disease. J Periodontol 1993; 64(10): 980-983.
32. Tamura M, Takada H. Bacteroides intermedius (Prevotella intermedia) lipopolysaccharide induced interleukin 8 mRNA in human gingival fibroblast cultures. Proc Int Conf Oral Biol, Osaka, Japan. 1992: 81.
33. Payne JB, Reinhartd RA, Masada MP, DuBois LM, Allison AC. Gingival crevicular fluid IL-8: correlation with local IL-1β levels and patient estrogen status. J Periodont Res 1993; 28: 451-453.
34. Tonetti MS, Freiburghaus K, Lang NP, Bickel M. Detection of IL-8 and matrix metalloproteinase transcripts in healthy and diseased gingival biopsies by RNA/PCR. J Periodont Res 1993; 28: 511-513.
35. Borinski R, Holt SC. Surface characteristics of Wolinella recta ATCC 33238 and human clinical isolates: correlation of structure with function. Infect Immun 1990; 58(9): 2770-76.
36. Thomson BM, Saklatvala J, Chambers TJ. Osteoclasts mediate IL-1 stimulation of bone resorption by rat osteoclasts. J Exp Med 1986; 164: 104.
37. Guerne PA, Carson DA, Lotz M. IL-6 production by human articular chrondrocytes. Modulation of its synthesis by cytokines, growth factors and hormones in vitro. J Immunol 1990; 144(2): 499-505.
38. Helgeland K, Nordby O. Cell cycle-specific growth inhibitory effect on human gingival fibroblasts of a toxin isolated from the culture medium of A. actinomycetemcomitans. J Perto Res 1993; 28: 161-165.
39. Socransky SS. Microbiology of periodontal disease: Present status and future considerations. J Periodontol 1977; 10: 465-77.
40. Zambon J. Studies of the subgingival microflora in patients with aquired immunodeficiency syndrome. J Periodontol 1990; 61: 699-704.
41. Tew J, Engel D, Mangan D. Polyclonal B-cell activation in periodontitis. J Periodont Res 1989; 24: 225-241.
42. Mundy GR Inflammatory mediators and the destruction of bone. J Periodont Res 1991; 26: 213-217
43. Thelen M, Peveri P, Kernen P, Von Tscharner V, Walz A, Baggiolini M. Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J 1: 2702-2706.
44. Taichman NS, Tsai C, Shenker BJ, Boehringer H. Neutrophil interactions with oral bacteria as a pathogenic mechanism in periodontal diseases. In: Weissmann G ed. Advances in inflammation research. New York: Raven Press, Vol 8, 1984: 113-142.
45. Harigai M, Hara M, Kitani A, Norioka K, Hirose T, Hirose W, Suzuki K, Kawakami M, Masuda K, Shinmei M, Kawagoe M, Nakamura H. Interleukin 1 and tumor necrosis factor alpha synergistically increase the production of interleukin 6 in human synovial fibroblasts. J Clin Lab Immunol 1991; 34: 107-113.
46. Rolfe MW, Kunkel SL, Standiford TJ, Chensue SW, Allen RM, Evanoff HL, Phan SH. Strieter RM. Pulmonary fibroblast expression of IL-8: a model for alveolar macrophage-derived cytokine network. Am J Resp Cell Mol Biol 1991; 5: 493-501.
47. Ohm K, Albers HK, Lisboa BP. Measurement of eight prostaglandins in human gingival and periodontal disease. Prostaglandins 1984; 19: 501-11.
48. Baer PN. The case for periodontosis as a clinical entity. J Periodontol 1971; 42(8): 516-20.
49. Burmeister JA, Best AM, Palkanis KG, Caine FA, Ranney RR. Localized juvenile periodontitis and generalized severe periodontitis: clinical findings. J Clin Periodontol 1984; 11: 181-92.
50. Hedges S, Svensson M, Svanborg C. Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro. Infect Immun 1992; 60(4): 1295-1301.
51. Bhakdi S, Klonisch T, Nuber P, Fischer W. Stimulation of monokine production by lipoteichoic acids. Infect Immun 1991; 59(12): 4614-4620.
52. Linder H, Eugberg I, Hoschutzki H, Mattsby-Baltzer I, Svanborg C. Adhesion-dependent activation of mucosal IL-6 production. Infect Immun 1991; 59: 4357-4362.
53. Scannapieco FA, Kornman KS, Conkendall AL. Observation of fimbriae and flagella in dispersed subgingival dental plaque and fresh bacterial isolates from periodontal disease. J Periodont Res 1983; 18: 620-8.
54. Rosan B, Slots J, Lamont RJ, Listgarten MA, Nelson GM. Actinobucillus actinomycetemcomitans fimbriae. Oral Microbiol Immunol 1988; 3: 58-65.