The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor

Biotechnology Letters

Volumn 31, Issue 7, 2009, Pages 939-944

  Liu, Xuping ^a   Wang, Yigang ^a   Niu, Hongxing ^a   Zhang, Xu ^a   Tan, Wen Song ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Adenovirus; CAR; Cell density effect; Cell specific productivity; HEK 293 cells

Indexed keywords

ADENOVIRAL VECTORS; ADENOVIRUS; ADENOVIRUS VECTOR; CAR; CELL DENSITY; CELL DENSITY EFFECT; CULTURE TIME; EXPRESSION LEVELS; GENE THERAPY; HEK 293 CELLS; HIGH CELL DENSITY; IN-CELL; INFECTED CELLS; SPECIFIC PRODUCTIVITY; TRICHOSTATIN A;

CELL MEMBRANES; GENETIC ENGINEERING; PRODUCTIVITY;

CELL CULTURE;

CAR RECEPTOR; ENZYME INHIBITOR; HYDROXAMIC ACID; TRICHOSTATIN A; VIRUS RECEPTOR;

ADENOVIRUS; ARTICLE; BIOSYNTHESIS; CELL LINE; CULTURE TECHNIQUE; GENE EXPRESSION PROFILING; GENE VECTOR; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN;

ADENOVIRIDAE; CELL CULTURE TECHNIQUES; CELL LINE; ENZYME INHIBITORS; GENE EXPRESSION PROFILING; GENETIC VECTORS; HUMANS; HYDROXAMIC ACIDS; RECEPTORS, VIRUS;

ADENOVIRIDAE; COXSACKIEVIRUS;

EID: 67649208277     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-009-9971-y     Document Type: Article

References (18)

1. CB Coyne JM Bergelson 2005 CAR: a virus receptor within the tight junction Adv Drug Deliv Rev 57 869 882 (Pubitemid 40488108)
2. TB Ferreira AL Ferreira MJT Carrondo PM Alves 2005 Effect of reefed strategies and non-ammoniagenic medium on adenovirus production at high cell densities J Biotechnol 119 272 280 (Pubitemid 41253689)
3. TB Ferreira AL Ferreira MJT Carrondo PM Alves 2005 Two different serum free media and osmolality effect upon 293 cell growth and adenovirus production Biotechnol Lett 27 1809 1813 (Pubitemid 41720288)
4. A Garnier J Cote I Nadeau A Kamen B Massie 1994 Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells Cytotechnology 15 145 155
5. O Henry E Dormond M Perrier A Kamen 2004 Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures Biotechnol Bioeng 86 765 774 (Pubitemid 38745694)
6. 2, and temperature effect on R-adenovirus production Biotechnol Prog 19 202 208 (Pubitemid 36219323)
7. A Kamen O Henry 2004 Development and optimization of an adenovirus production process J Gen Med 6 184 192
8. LKM Kauwe 2003 Endocytosis of adenovirus and adenovirus capsid proteins Adv Drug Deliv Rev 55 1485 1496
9. M Kim KR Zinn BG Barnett LA Sumerel V Krasnykh DT Curiel JT Douglas 2002 The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells Eur J Cancer 38 1917 1926 (Pubitemid 35247478)
10. LK Law BL Davidson 2005 What does it take to bind CAR? Mol Ther 12 599 609 (Pubitemid 41350141)
11. K Matsumoto SF Shariat GE Ayala KA Rauen SP Lerner 2005 Loss of coxsackie and adenovirus receptor expression is associated with features of aggressive bladder cancer Urology 66 441 446 (Pubitemid 41138121)
12. I Nadeau A Kamen 2003 Production of adenovirus vector for gene therapy Biotechnol Adv 20 475 489 (Pubitemid 36010677)
13. I Nadeau A Garnier J Cote B Massie C Chavarie A Kamen 1996 Improvement of recombinant protein production with human adenovirus/293S expression system using fed-batch strategies Biotechnol Bioeng 51 613 623 (Pubitemid 26284951)
14. H Nagel S Maag A Tassis FO Nestle UF Greber S Hemmi 2003 The αvβ5 integrin of hematopoietic and nonheatopoietic cells is a transduction receptor of RGD-4C fiber-modified adenoviruses Gene Ther 10 1643 1653 (Pubitemid 37069492)
15. GR Nemerow 2000 Cell receptors involved in adenovirus entry Virology 274 1 4 (Pubitemid 30650675)
16. JC Reichert CJ Rosensweig LB Faden MC Dewitz 2005 Monoclonal antibody successes in the clinic Nat Biotechnol 23 1073 1078 (Pubitemid 41486385)
17. MA Seidman SM Hogan RL Wendland S Worgall RG Crystal PL Leopold 2001 Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle Mol Ther 4 13 21 (Pubitemid 32684697)
18. C Zhang TB Ferreira PE Cruz PM Alves M Haury MJT Carrondo 2006 The importance of 293 cell cycle phase on adenovirus vector production Enzyme Microb Technol 39 1328 1332 (Pubitemid 44247157)