Leishmania (Viannia) peruviana (MHOM/PE/LCA08): Comparison of THP-1 cell and murine macrophage susceptibility to axenic amastigotes for the screening of leishmanicidal compounds

Experimental Parasitology

Volumn 122, Issue 4, 2009, Pages 353-356

  González, Germán ^a   Castillo, Denis ^a   Estevez, Yannick ^b   Grentzinger, Thomas ^c   Deharo, Eric ^b,c  

^a UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (Peru)

Author keywords

Amphotericin B; Leishmania; Leishmania peruviana; Leishmanicidal; Murine macrophages; THP 1

Indexed keywords

AMPHOTERICIN B; ANTILEISHMANIAL AGENT;

AMASTIGOTE; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; LEISHMANIA; LEISHMANIA PERUVIANA; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA BRAZILIENSIS; LEUKEMIA, MONOCYTIC, ACUTE; MACROPHAGES, PERITONEAL; MICE; MONOCYTES;

LEISHMANIA PERUVIANA; MURINAE;

EID: 67649083631     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2009.05.005     Document Type: Article

References (16)

1. Buckner F.S., and Wilson A.J. Colorimetric assay for screening compounds against leishmania amastigotes grown in macrophages. American Journal of Tropical Medicine and Hygiene 72 (2005) 600-605
2. Castillo D., Arevalo J., Herrera F., Ruiz C., Rojas R., Rengifo E., Vaisberg A., Lock O., Lemesre J.L., Gornitzka H., and Sauvain M. Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae). Journal of Ethnopharmacology 112 (2007) 410-414
3. Delorenzi J.C., Attias M., Gattass C.R., Andrade M., Rezende C., da Cunha Pinto A., Henriques A.T., Bou-Habib D.C., and Saraiva E.M. Antileishmanial activity of an indole alkaloid from Peschiera australis. Antimicrobial Agents and Chemotherapy 45 (2001) 1349-1354
4. Desjeux P. Leishmaniasis: current situation and new perspectives. Comparative Immunology and Microbiology Infected Disease 27 (2004) 305-318
5. Escobar P., Matu S., Marques C., and Croft S.L. Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta Tropica 81 (2002) 151-157
6. Fautz R., Husein B., and Hechenberger C. Application of the neutral red assay (NR assay) to monolayer cultures of primary hepatocytes: rapid colorimetric viability determination for the unscheduled DNA synthesis test (UDS). Mutation Research 253 (1991) 173-179
7. Gebre-Hiwot A., Tadesse G., Croft S.L., and Frommel D. An in vitro model for screening antileishmanial drugs: the human leukaemia monocyte cell line, THP-1. Acta Tropica 51 (1992) 237-245
8. Mehta R., Lopez-Berestein G., Hopfer R., Mills K., and Juliano R.L. Liposomal amphotericin B is toxic to fungal cells but not to mammalian cells. Biochemical Biophysics Acta 770 (1984) 230-234
9. Ogunkolade B.W., Colomb-Valet I., Monjour L., Rhodes-Feuillette A., Abita J.P., and Frommel D. Interactions between the human monocytic leukaemia THP-1 cell line and Old and New World species of Leishmania. Acta Tropica 47 (1990) 171-176
10. Park E.K., Jung H.S., Yang H.I., Yoo M.C., Kim C., and Kim K.S. Optimized THP-1 differentiation is required for the detection of responses to weak stimuli. Inflammation Research 56 (2007) 45-50
11. Rogers P.D., Barker K.S., Herring V., and Jacob M. Heat-induced superaggregation of amphotericin B attenuates its ability to induce cytokine and chemokine production in the human monocytic cell line THP-1. The Journal of Antimicrobial Chemotherapy 51 (2003) 405-408
12. Sánchez L., Saenz E., Pancorbo J., Zegarra R., Garces N., and Regis A. Leishmaniasis. Dermatolgía Peruana 14 (2004) 82-98
13. Sau K., Mambula S.S., Latz E., Henneke P., Golenbock D.T., and Levitz S.M. The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism. Journal of Biological Chemistry 278 39 (2003) 37561-37568
14. Sauvain M., Dedet J.P., Kunesch N., Poisson J., Gayral P., Gantier J.C., and Kunesch G. In vitro and in vivo leishmanicidal activities of natural and synthetic quinoids. Phytotherapy Research 7 (1993) 167-171
15. Teixeira M.C., de Jesus Santos R., Sampaio R.B., Pontes-de-Carvalho L., and dos-Santos W.L. A simple and reproducible method to obtain large numbers of axenic amastigotes of different Leishmania species. Parasitology Research 88 (2002) 963-968
16. Worley J.R., Baugh M.D., Hughes D.A., Edwards D.R., Hogan A., Sampson M.J., and Gavrilovic J. Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. Journal of Biological Chemistry 278 (2003) 51340-51346