Heat-induced superaggregation of amphotericin B attenuates its ability to induce cytokine and chemokine production in the human monocytic cell line THP-1

Journal of Antimicrobial Chemotherapy

Volumn 51, Issue 2, 2003, Pages 405-408

  Rogers, P David ^a   Barker, Katherine S ^a   Herring, Vanessa ^a   Jacob, Melissa ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Amphotericin B; Chemokine; Cytokine; Monocyte

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B DERIVATIVE; CHEMOKINE; CYTOKINE; INTERLEUKIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA TROPICALIS; CELL LINE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFICACY; HEAT TREATMENT; HUMAN; HUMAN CELL; MONOCYTE; PROTEIN INDUCTION;

AMPHOTERICIN B; ANTI-BACTERIAL AGENTS; CELL AGGREGATION; CELL LINE; CHEMOKINES; CYTOKINES; FUNGI; HEAT; HUMANS; INDICATORS AND REAGENTS; MICROBIAL SENSITIVITY TESTS; MONOCYTES;

EID: 0037329733     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg070     Document Type: Article

References (10)

1. Gallis, H. A., Drew, R. H. & Pickard, W. W. (1990). Amphotericin B: 30 years of clinical experience. Review of Infectious Diseases 12, 308-29.
2. Gaboriau, F., Cheron, M., Petit, C. & Bolard, J. (1997). Heat-induced superaggregation of amphotericin B reduces its in vitro toxicity: a new way to improve its therapeutic index. Antimicrobial Agents and Chemotherapy 41, 2345-51.
3. Hartsel, S. C., Baas, B., Bauer, E., Foree, L. T. Jr, Kindt, K., Preis, H. et al. (2001). Heat-induced superaggregation of amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha. Journal of Pharmaceutical Sciences 90, 124-33.
4. Petit, C., Cheron, M., Joly, V., Rodrigues, J. M., Bolard, J. & Gaboriau, F. (1998). In-vivo therapeutic efficacy in experimental murine mycoses of a new formulation of deoxycholate-amphotericin B obtained by mild heating. Journal of Antimicrobial Chemotherapy 42, 779-85.
5. Kwong, E. H., Ramaswamy, M., Bauer, E. A., Hartsel, S. C. & Wasan, K. M. (2001). Heat treatment of amphotericin B modifies its serum pharmacokinetics, tissue distribution, and renal toxicity following administration of a single intravenous dose to rabbits. Anti-microbial Agents and Chemotherapy 45, 2060-3.
6. Rogers, P. D., Jenkins, J. K., Chapman, S. W., Ndebele, K., Chapman, B. A. & Cleary, J. D. (1998). Amphotericin B activation of human genes encoding for cytokines. Journal of Infectious Diseases 178, 1726-33.
7. National Committee for Clinical Laboratory Standards. (1997). Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts: Approved Standard M27-A, Vol. 17, No. 9. NCCLS, Villanova, PA, USA.
8. Rogers, P. D., Stiles, J. K., Chapman, S. W. & Cleary, J. D. (2000). Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1. Journal of Infectious Diseases 182, 1280-3.
9. Goodwin, S. D., Cleary, J. D., Walawander, C. A., Taylor, J. W. & Grasela, T. H. (1995). Pretreatment regimens for adverse events related to infusion of amphotericin B. Clinical Infectious Diseases 20, 755-61.
10. Chia, J. K. & Pollack, M. (1989). Amphotericin B induces tumor necrosis factor production by murine macrophages. Journal of Infectious Diseases 159, 113-6.