메뉴 건너뛰기




Volumn 380, Issue 2, 2009, Pages 99-107

Signaling properties of human α1D-adrenoceptors lacking the carboxyl terminus: Intrinsic activity, agonist-mediated activation, and desensitization

Author keywords

1 Adrenoceptors; 1D Adrenoceptors; Adrenergic receptors; Desensitization; Receptor phosphorylation

Indexed keywords

ALPHA 1D ADRENERGIC RECEPTOR; NORADRENALIN; PROTEIN KINASE C;

EID: 67449161559     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-009-0428-6     Document Type: Article
Times cited : (8)

References (32)
  • 1
    • 0020595443 scopus 로고
    • Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides
    • MJ Berridge RM Dawson CP Downes JP Heslop RF Irvine 1983 Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides Biochem J 212 473 482
    • (1983) Biochem J , vol.212 , pp. 473-482
    • Berridge, M.J.1    Dawson, R.M.2    Downes, C.P.3    Heslop, J.P.4    Irvine, R.F.5
  • 3
    • 33744962233 scopus 로고    scopus 로고
    • 1D-adrenergic receptors through a PDZ domain-mediated interaction
    • DOI 10.1074/jbc.M508651200
    • Z Chen C Hague RA Hall KP Minneman 2006 Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction J Biol Chem 281 12414 12420 (Pubitemid 43855326)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.18 , pp. 12414-12420
    • Chen, Z.1    Hague, C.2    Hall, R.A.3    Minneman, K.P.4
  • 4
    • 0030699386 scopus 로고    scopus 로고
    • Characterization of the phosphorylation sites involved in G protein- coupled receptor kinase- and protein kinase C-mediated desensitization of the α(1B)-adrenergic receptor
    • DOI 10.1074/jbc.272.45.28712
    • D Diviani AL Lattion S Cotecchia 1997 Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor J Biol Chem 272 28712 28719 (Pubitemid 27517828)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.45 , pp. 28712-28719
    • Diviani, D.1    Lattion, A.-L.2    Cotecchia, S.3
  • 5
    • 0032999420 scopus 로고    scopus 로고
    • Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing α(1d)- adrenoceptors
    • DOI 10.1016/S0014-5793(98)01738-4, PII S0014579398017384
    • JA García-Sáinz ME Torres-Padilla 1999 Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors FEBS Lett 443 277 281 (Pubitemid 29080810)
    • (1999) FEBS Letters , vol.443 , Issue.3 , pp. 277-281
    • Garcia-Sainz, J.A.1    Torres-Padilla, M.E.2
  • 6
    • 4644240094 scopus 로고    scopus 로고
    • 1D-adrenoceptor: Molecular and cellular characteristics and integrative roles
    • DOI 10.1016/j.ejphar.2004.07.016, PII S0014299904007253
    • JA García-Sáinz R Villalobos-Molina 2004 The elusive alpha(1D)-adrenoceptor: molecular and cellular characteristics and integrative roles Eur J Pharmacol 500 113 120 (Pubitemid 39304001)
    • (2004) European Journal of Pharmacology , vol.500 , Issue.1-3 SPEC. ISS. , pp. 113-120
    • Garcia-Sainz, J.A.1    Villalobos-Molina, R.2
  • 7
    • 0342614935 scopus 로고    scopus 로고
    • 1-Adrenoceptors: Subtypes, signaling, and roles in health and disease
    • DOI 10.1016/S0188-0128(99)00059-7, PII S0188012899000597
    • JA García-Sáinz J Vázquez-Prado R Villalobos-Molina 1999 Alpha 1-adrenoceptors: subtypes, signaling, and roles in health and disease Arch Med Res 30 449 458 (Pubitemid 30067558)
    • (1999) Archives of Medical Research , vol.30 , Issue.6 , pp. 449-458
    • Garcia-Sainz, J.A.1    Vazquez-Prado, J.2    Villalobos-Molina, R.3
  • 10
    • 2342508451 scopus 로고    scopus 로고
    • 1D-adrenoceptor phosphorylation and desensitization
    • DOI 10.1016/j.bcp.2004.01.025, PII S0006295204001066
    • JA García-Sáinz CE Rodríguez-Pérez MT Romero-Ávila 2004 Human alpha-1D adrenoceptor phosphorylation and desensitization Biochem Pharmacol 67 1853 1858 (Pubitemid 38591374)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.10 , pp. 1853-1858
    • Garcia-Sainz, J.A.1    Rodriguez-Perez, C.E.2    Romero-Avila, M.T.3
  • 13
    • 0029874397 scopus 로고    scopus 로고
    • Alpha 1-adrenergic receptor subtypes. Molecular structure, function, and signaling
    • RM Graham DM Perez J Hwa MT Piascik 1996 alpha 1-adrenergic receptor subtypes. Molecular structure, function, and signaling Circ Res 78 737 749
    • (1996) Circ Res , vol.78 , pp. 737-749
    • Graham, R.M.1    Perez, D.M.2    Hwa, J.3    Piascik, M.T.4
  • 14
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • G Grynkiewicz M Poenie RY Tsien 1985 A new generation of Ca2+ indicators with greatly improved fluorescence properties J Biol Chem 260 3440 3450 (Pubitemid 15114340)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.6 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 16
    • 0028059202 scopus 로고
    • Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor
    • AL Lattion D Diviani S Cotecchia 1994 Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor J Biol Chem 269 22887 22893
    • (1994) J Biol Chem , vol.269 , pp. 22887-22893
    • Lattion, A.L.1    Diviani, D.2    Cotecchia, S.3
  • 19
    • 0029790928 scopus 로고    scopus 로고
    • Functional evidence of inverse agonism in vascular smooth muscle
    • MA Noguera MD Ivorra P D'Ocon 1996 Functional evidence of inverse agonism in vascular smooth muscle Br J Pharmacol 119 158 164 (Pubitemid 26294535)
    • (1996) British Journal of Pharmacology , vol.119 , Issue.1 , pp. 158-164
    • Noguera, M.A.1    Ivorra, M.D.2    D'Ocon, P.3
  • 21
    • 0037088693 scopus 로고    scopus 로고
    • 1aAR splice variants
    • DOI 10.1074/jbc.M111762200
    • RR Price DP Morris G Biswas MP Smith DA Schwinn 2002 Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants J Biol Chem 277 9570 9579 (Pubitemid 34953046)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 9570-9579
    • Reyn Price, R.1    Morris, D.P.2    Biswas, G.3    Smith, M.P.4    Schwinn, D.A.5
  • 22
    • 50449087030 scopus 로고    scopus 로고
    • Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: The potential role of receptor interaction with beta-arrestins and AP50
    • L Stanasila L Abuin J Dey S Cotecchia 2008 Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50 Mol Pharmacol 74 562 573
    • (2008) Mol Pharmacol , vol.74 , pp. 562-573
    • Stanasila, L.1    Abuin, L.2    Dey, J.3    Cotecchia, S.4
  • 23
    • 0037183775 scopus 로고    scopus 로고
    • 1-adrenergic receptor subtype function
    • DOI 10.1016/S0024-3205(02)02012-X, PII S002432050202012X
    • A Tanoue TA Koshimizu G Tsujimoto 2002 Transgenic studies of alpha(1)-adrenergic receptor subtype function Life Sci 71 2207 2215 (Pubitemid 35246209)
    • (2002) Life Sciences , vol.71 , Issue.19 , pp. 2207-2215
    • Tanoue, A.1    Koshimizu, T.-A.2    Tsujimoto, G.3
  • 25
    • 0029975437 scopus 로고    scopus 로고
    • 1-adrenoceptor subtypes
    • J Vázquez-Prado JA García-Sáinz 1996 Effect of phorbol myristate acetate on alpha 1-adrenergic action in cells expressing recombinant alpha 1-adrenoceptor subtypes Mol Pharmacol 50 17 22 (Pubitemid 26250070)
    • (1996) Molecular Pharmacology , vol.50 , Issue.1 , pp. 17-22
    • Vazquez-Prado, J.1    Garcia-Sainz, J.A.2
  • 26
    • 0031585419 scopus 로고    scopus 로고
    • Activation of endothelin ET(A) receptors induces phosphorylation of α(1b)-adrenoreceptors in rat-1 fibroblasts
    • DOI 10.1074/jbc.272.43.27330
    • J Vázquez-Prado LC Medina JA García-Sáinz 1997 Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts J Biol Chem 272 27330 27337 (Pubitemid 27452699)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.43 , pp. 27330-27337
    • Vazquez-Prado, J.1    Medina, L.D.C.2    Garcia-Sainz, J.A.3
  • 28
    • 0029670133 scopus 로고    scopus 로고
    • Alpha 1-adrenoceptors mediating contraction in arteries of normotensive and spontaneously hypertensive rats are of the alpha 1D or alpha 1A subtypes
    • R Villalobos-Molina M Ibarra 1996 Alpha 1-adrenoceptors mediating contraction in arteries of normotensive and spontaneously hypertensive rats are of the alpha 1D or alpha 1A subtypes Eur J Pharmacol 298 257 263
    • (1996) Eur J Pharmacol , vol.298 , pp. 257-263
    • Villalobos-Molina, R.1    Ibarra, M.2
  • 29
    • 0032724573 scopus 로고    scopus 로고
    • Vascular alpha 1D-adrenoceptors: Are they related to hypertension?
    • R Villalobos-Molina M Ibarra 1999 Vascular alpha 1D-adrenoceptors: are they related to hypertension? Arch Med Res 30 347 352
    • (1999) Arch Med Res , vol.30 , pp. 347-352
    • Villalobos-Molina, R.1    Ibarra, M.2
  • 30
    • 0032588032 scopus 로고    scopus 로고
    • Functional evidence of α(1D)-adrenoceptors in the vasculature of young and adult spontaneously hypertensive rats
    • R Villalobos-Molina JJ López-Guerrero M Ibarra 1999 Functional evidence of alpha1D-adrenoceptors in the vasculature of young and adult spontaneously hypertensive rats Br J Pharmacol 126 1534 1536 (Pubitemid 29182335)
    • (1999) British Journal of Pharmacology , vol.126 , Issue.7 , pp. 1534-1536
    • Villalobos-Molina, R.1    Lopez-Guerrero, J.J.2    Ibarra, M.3
  • 32
    • 0344718782 scopus 로고    scopus 로고
    • 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension
    • DOI 10.1097/00004872-200311000-00002
    • JA Whitworth 2003 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension J Hypertens 21 1983 1992 (Pubitemid 38296854)
    • (2003) Journal of Hypertension , vol.21 , Issue.11 , pp. 1983-1992
    • Whitworth, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.