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Volumn 89, Issue 4, 2009, Pages 470-481

Possible involvement of RasGRP4 in leukemogenesis

Author keywords

AML1; CDNA library; Class I mutation; Leukemogenesis; RasGRP4

Indexed keywords

COMPLEMENTARY DNA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAS GUANYL RELEASING PROTEIN 4; UNCLASSIFIED DRUG; RASGRP4 PROTEIN, HUMAN; RASGRP4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR RUNX1;

EID: 67449116506     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-009-0299-0     Document Type: Article
Times cited : (18)

References (39)
  • 3
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese ChildhoodAMLCooperative Study Group
    • DOI 10.1182/blood-2005-08-3408
    • A Shimada T Taki K Tabuchi A Tawa K Horibe M Tsuchida 2006 KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group Blood 107 1806 1809 10.1182/blood-2005-08-3408 (Pubitemid 43289357)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 7
    • 3943068350 scopus 로고    scopus 로고
    • KIT activating mutations: Incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication
    • A Beghini CB Ripamonti R Cairoli G Cazzaniga P Colapietro F Elice 2004 KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication Haematologica 89 920 925
    • (2004) Haematologica , vol.89 , pp. 920-925
    • Beghini, A.1    Ripamonti, C.B.2    Cairoli, R.3    Cazzaniga, G.4    Colapietro, P.5    Elice, F.6
  • 8
    • 28544448340 scopus 로고    scopus 로고
    • Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia
    • DOI 10.1038/sj.leu.2404009, PII 2404009
    • DH Christiansen MK Andersen F Desta J Pedersen-Bjergaard 2005 Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia Leukemia 19 2232 2240 10.1038/sj.leu.2404009 (Pubitemid 41741619)
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2232-2240
    • Christiansen, D.H.1    Andersen, M.K.2    Desta, F.3    Pedersen-Bjergaard, J.4
  • 9
    • 33646475438 scopus 로고    scopus 로고
    • Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations
    • 10.1038/sj.leu.2404136
    • H Niimi H Harada Y Harada Y Ding J Imagawa T Inaba 2006 Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations Leukemia 20 635 644 10.1038/sj.leu.2404136
    • (2006) Leukemia , vol.20 , pp. 635-644
    • Niimi, H.1    Harada, H.2    Harada, Y.3    Ding, Y.4    Imagawa, J.5    Inaba, T.6
  • 14
    • 0037219507 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication in childhood acute myeloid leukaemia: Association with hyperleucocytosis in acute promyelocytic leukaemia
    • DOI 10.1046/j.1365-2141.2003.04032.x
    • P Arrigoni C Beretta D Silvestri V Rossi C Rizzari MG Valsecchi 2003 FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia Br J Haematol 120 89 92 10.1046/j.1365-2141.2003.04032.x (Pubitemid 36056913)
    • (2003) British Journal of Haematology , vol.120 , Issue.1 , pp. 89-92
    • Arrigoni, P.1    Beretta, C.2    Silvestri, D.3    Rossi, V.4    Rizzari, C.5    Valsecchi, M.G.6    Cazzaniga, G.7    Biondi, A.8
  • 15
    • 0036850573 scopus 로고    scopus 로고
    • Alterations of the FLT3 gene in acute promyelocytic leukemia: Association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
    • DOI 10.1038/sj.leu.2402723
    • NI Noguera M Breccia M Divona D Diverio V Costa S De Santis 2002 Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol Leukemia 16 2185 2189 10.1038/sj.leu.2402723 (Pubitemid 35331832)
    • (2002) Leukemia , vol.16 , Issue.11 , pp. 2185-2189
    • Noguera, N.I.1    Breccia, M.2    Divona, M.3    Diverio, D.4    Costa, V.5    De Santis, S.6    Avvisati, G.7    Pinazzi, M.B.8    Petti, M.C.9    Mandelli, F.10    Lo Coco, F.11
  • 17
    • 9144244169 scopus 로고    scopus 로고
    • FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
    • DOI 10.1182/blood-2003-02-0418
    • T Taketani T Taki K Sugita Y Furuichi E Ishii R Hanada 2004 FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy Blood 103 1085 1088 10.1182/blood-2003-02-0418 (Pubitemid 38129575)
    • (2004) Blood , vol.103 , Issue.3 , pp. 1085-1088
    • Taketani, T.1    Taki, T.2    Sugita, K.3    Furuichi, Y.4    Ishii, E.5    Hanada, R.6    Tsuchida, M.7    Sugita, K.8    Ida, K.9    Hayashi, Y.10
  • 19
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • 10.1182/blood-2007-08-109090
    • RE Gale C Green C Allen AJ Mead AK Burnett RK Hills 2008 The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia Blood 111 2776 2784 10.1182/blood-2007-08-109090
    • (2008) Blood , vol.111 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, C.3    Mead, A.J.4    Burnett, A.K.5    Hills, R.K.6
  • 20
    • 0033134792 scopus 로고    scopus 로고
    • Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
    • H Kiyoi T Naoe Y Nakano S Yokota S Minami S Miyawaki 1999 Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia Blood 93 3074 3080
    • (1999) Blood , vol.93 , pp. 3074-3080
    • Kiyoi, H.1    Naoe, T.2    Nakano, Y.3    Yokota, S.4    Minami, S.5    Miyawaki, S.6
  • 21
    • 0035383768 scopus 로고    scopus 로고
    • FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
    • 10.1182/blood.V97.11.3589
    • DL Stirewalt KJ Kopecky S Meshinchi FR Appelbaum ML Slovak CL Willman 2001 FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia Blood 97 3589 3595 10.1182/blood.V97.11.3589
    • (2001) Blood , vol.97 , pp. 3589-3595
    • Stirewalt, D.L.1    Kopecky, K.J.2    Meshinchi, S.3    Appelbaum, F.R.4    Slovak, M.L.5    Willman, C.L.6
  • 23
    • 27144477007 scopus 로고    scopus 로고
    • Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells
    • DOI 10.1038/sj.leu.2403917, PII 2403917
    • JK Warner JC Wang K Takenaka S Doulatov JL McKenzie L Harrington 2005 Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells Leukemia 19 1794 1805 10.1038/sj.leu.2403917 (Pubitemid 41486158)
    • (2005) Leukemia , vol.19 , Issue.10 , pp. 1794-1805
    • Warner, J.K.1    Wang, J.C.Y.2    Takenaka, K.3    Doulatov, S.4    McKenzie, J.L.5    Harrington, L.6    Dick, J.E.7
  • 24
    • 0036014968 scopus 로고    scopus 로고
    • Role of FLT3 in leukemia
    • DOI 10.1097/00062752-200207000-00003
    • DG Gilliland JD Griffin 2002 Role of FLT3 in leukemia Curr Opin Hematol 9 274 281 10.1097/00062752-200207000-00003 (Pubitemid 34596870)
    • (2002) Current Opinion in Hematology , vol.9 , Issue.4 , pp. 274-281
    • Gilliland, D.G.1    Griffin, J.D.2
  • 26
    • 0035857078 scopus 로고    scopus 로고
    • Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia
    • DOI 10.1038/sj.onc.1205095
    • GM Cuenco R Ren 2001 Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia Oncogene 20 8236 8248 10.1038/sj.onc.1205095 (Pubitemid 34038211)
    • (2001) Oncogene , vol.20 , Issue.57 , pp. 8236-8248
    • Cuenco, G.M.1    Ren, R.2
  • 27
    • 16844380787 scopus 로고    scopus 로고
    • Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis
    • R Ono H Nakajima K Ozaki H Kumagai T Kawashima T Taki 2005 Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis J Clin Invest 115 919 929
    • (2005) J Clin Invest , vol.115 , pp. 919-929
    • Ono, R.1    Nakajima, H.2    Ozaki, K.3    Kumagai, H.4    Kawashima, T.5    Taki, T.6
  • 30
    • 0037067713 scopus 로고    scopus 로고
    • RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
    • DOI 10.1074/jbc.M202575200
    • Y Yang L Li GW Wong SA Krilis MS Madhusudhan A Sali 2002 RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function J Biol Chem 277 25756 25774 10.1074/jbc.M202575200 (Pubitemid 34951897)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25756-25774
    • Yang, Y.1    Li, X.2    Wong, G.W.3    Krilis, S.A.4    Madhusudhan, M.S.5    Sali, A.6    Stevens, R.L.7
  • 32
    • 0142227052 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics
    • T Kitamura Y Koshino F Shibata T Oki H Nakajima T Nosaka 2003 Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics Exp Hematol 31 1007 1014
    • (2003) Exp Hematol , vol.31 , pp. 1007-1014
    • Kitamura, T.1    Koshino, Y.2    Shibata, F.3    Oki, T.4    Nakajima, H.5    Nosaka, T.6
  • 33
    • 1542373639 scopus 로고    scopus 로고
    • High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia
    • DOI 10.1182/blood-2003-09-3074
    • H Harada Y Harada H Niimi T Kyo A Kimura T Inaba 2004 High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia Blood 103 2316 2324 10.1182/blood-2003-09-3074 (Pubitemid 38326252)
    • (2004) Blood , vol.103 , Issue.6 , pp. 2316-2324
    • Harada, H.1    Harada, Y.2    Niimi, H.3    Kyo, T.4    Kimura, A.5    Inaba, T.6
  • 35
    • 43249103972 scopus 로고    scopus 로고
    • AML1 mutations induced MDS and MDS/AML in a mouse BMT model
    • 10.1182/blood-2007-01-068346
    • N Watanabe-Okochi J Kitaura R Ono H Harada Y Harada Y Komeno 2008 AML1 mutations induced MDS and MDS/AML in a mouse BMT model Blood 111 4297 4308 10.1182/blood-2007-01-068346
    • (2008) Blood , vol.111 , pp. 4297-4308
    • Watanabe-Okochi, N.1    Kitaura, J.2    Ono, R.3    Harada, H.4    Harada, Y.5    Komeno, Y.6
  • 36
    • 0028010868 scopus 로고
    • AML: Immunophenotypic heterogeneity and prognostic significance of c-kit expression
    • MA Reuss-Borst HJ Bühring H Schmidt CA Müller 1994 AML: immunophenotypic heterogeneity and prognostic significance of c-kit expression Leukemia 8 258 263
    • (1994) Leukemia , vol.8 , pp. 258-263
    • Reuss-Borst, M.A.1    Bühring, H.J.2    Schmidt, H.3    Müller, C.A.4
  • 37
    • 41649109612 scopus 로고    scopus 로고
    • Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA
    • 10.1038/sj.onc.1210857
    • Y Chinen T Taki K Nishida D Shimizu T Okuda N Yoshida 2008 Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA Oncogene 27 2249 2256 10.1038/sj.onc.1210857
    • (2008) Oncogene , vol.27 , pp. 2249-2256
    • Chinen, Y.1    Taki, T.2    Nishida, K.3    Shimizu, D.4    Okuda, T.5    Yoshida, N.6
  • 39
    • 0031872042 scopus 로고    scopus 로고
    • New experimental approaches in retrovirus-mediated expression screening
    • 10.1016/S0925-5710(98)00025-5
    • T Kitamura 1998 New experimental approaches in retrovirus-mediated expression screening Int J Hematol 67 351 359 10.1016/S0925-5710(98)00025-5
    • (1998) Int J Hematol , vol.67 , pp. 351-359
    • Kitamura, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.