ANA deficiency enhances bone morphogenetic protein-induced ectopic bone formation via transcriptional events

Journal of Biological Chemistry

Volumn 284, Issue 16, 2009, Pages 10593-10600

  Miyai, Kentaro ^a,b   Yoneda, Mitsuhiro ^c   Hasegawa, Urura ^a   Toita, Sayaka ^a   Izu, Yayoi ^a   Hemmi, Hiroaki ^a   Hayata, Tadayoshi ^a   Ezura, Yoichi ^a   Mizutani, Shuki ^b   Miyazono, Kohei ^d   Akiyoshi, Kazunari ^a   Yamamoto, Tadashi ^c   Noda, Masaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-PROLIFERATIVE; BONE METABOLISM; BONE MORPHOGENETIC PROTEINS; BRAIN INJURY; C2C12 CELLS; ECTOPIC BONES; IMMUNOPRECIPITATION ASSAYS; IN-VITRO; IN-VIVO; JOINT REPLACEMENT; MC3T3-E1; MRNA LEVEL; NEGATIVE FEEDBACK; OSTEOBLASTIC CELLS; OSTEOBLASTIC DIFFERENTIATION; OVER-EXPRESSION; REPORTER GENE; RESPONSE ELEMENTS; SMALL INTERFERENCE RNA; WILD TYPES;

CELL MEMBRANES; FEEDBACK; JOINT PROSTHESES; MUSCLE; NUCLEIC ACIDS; PROTEINS; RNA;

BONE;

ABUNDANT IN NEUROEPITHELIAL AREA PROTEIN; BONE MORPHOGENETIC PROTEIN 2; CELL CYCLE PROTEIN; LUCIFERASE; MESSENGER RNA; SMAD8 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BONE MORPHOGENETIC PROTEIN; BTG3 PROTEIN, MOUSE; ISOPROTEIN; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE METABOLISM; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEGATIVE FEEDBACK; NEWBORN; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REPORTER GENE; RNA INTERFERENCE; THREE DIMENSIONAL IMAGING; WILD TYPE; ANIMAL; BONE; BONE DEVELOPMENT; C57BL MOUSE; CELL STRAIN 3T3; CYTOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

MUS;

3T3 CELLS; ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEINS; GENES, REPORTER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOGENESIS; PROTEIN ISOFORMS; PROTEINS; RNA, SMALL INTERFERING; SMAD8 PROTEIN; TRANSCRIPTION, GENETIC;

EID: 67449096527     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807677200     Document Type: Article

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