Phosphorylation of three regulatory serines of Tob by ErK1 and ErK2 is required for Ras-mediated cell proliferation and transformation

Genes and Development

Volumn 16, Issue 11, 2002, Pages 1357-1370

  Suzuki, Toru ^a   K Tsuzuku, Junko ^a   Ajima, Rieko ^a   Nakamura, Takahisa ^a   Yoshida, Yutaka ^a   Yamamoto, Tadashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cell cycle entry; Ras MAPK pathway; Tob phosphorylation

Indexed keywords

CYCLIN D1; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN TOB; RAS PROTEIN; REGULATOR PROTEIN; SERINE; UNCLASSIFIED DRUG; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALANINE; CARRIER PROTEIN; ENZYME INHIBITOR; FLAVONOID; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE TRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOSERINE; TOB1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GROWTH INHIBITION; MOUSE; MULTIGENE FAMILY; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; BIOSYNTHESIS; CELL CYCLE; CELL CYCLE G0 PHASE; CELL DIVISION; CELL STRAIN 3T3; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; METABOLISM; PEPTIDE MAPPING; PHOSPHORYLATION; PLASMID; PROTEIN TERTIARY STRUCTURE; TIME;

ANIMALIA;

3T3 CELLS; ALANINE; ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN D1; ENZYME INHIBITORS; FLAVONOIDS; G0 PHASE; G1 PHASE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE TRANSFERASE; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE MAPPING; PHOSPHORYLATION; PHOSPHOSERINE; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; RAS PROTEINS; S PHASE; SERINE; TIME FACTORS; TRANSFECTION;

EID: 0036594619     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.962802     Document Type: Article

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